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ONTOLOGY REPORT - ANNOTATIONS


Term:RNA destabilization
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Accession:GO:0050779 term browser browse the term
Definition:Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.


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RNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dxo decapping exoribonuclease JBrowse link 20 4,517,307 4,519,391 RGD:1624291
RGD:1600115
G Lin28b lin-28 homolog B JBrowse link 20 50,482,536 50,580,273 RGD:1600115
RGD:1624291
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 JBrowse link 1 255,660,165 255,842,671 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Dnd1 DND microRNA-mediated repression inhibitor 1 JBrowse link 18 29,608,588 29,611,212 RGD:1600115
RGD:1624291
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:10042974
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:1600115
RGD:1624291
G Mov10 Mov10 RISC complex RNA helicase JBrowse link 2 207,277,088 207,301,245 RGD:1624291
G Plekhn1 pleckstrin homology domain containing N1 JBrowse link 5 173,646,055 173,654,140 RGD:1624291
G Qk quaking JBrowse link 1 50,983,647 51,050,692 RGD:1624291
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Tardbp TAR DNA binding protein JBrowse link 5 165,432,089 165,442,232 RGD:1600115
RGD:1624291
G Trim71 tripartite motif containing 71 JBrowse link 8 122,553,015 122,604,787 RGD:1624291
G Upf1 UPF1, RNA helicase and ATPase JBrowse link 16 20,824,888 20,845,632 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
G Zc3h12d zinc finger CCCH type containing 12D JBrowse link 1 1,937,620 1,972,919 RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1600115
RGD:1624291
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 6 103,308,032 103,313,074 RGD:1600115
RGD:1624291
G Zfp36l2 zinc finger protein 36, C3H type-like 2 JBrowse link 6 7,417,416 7,423,447 RGD:1624291
mRNA destabilization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnot6l CCR4-NOT transcription complex, subunit 6-like JBrowse link 14 15,059,101 15,148,255 RGD:1624291
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1600115
RGD:1624291
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link 9 94,425,191 94,550,431 RGD:1624291
G Hnrnpr heterogeneous nuclear ribonucleoprotein R JBrowse link 5 154,668,194 154,699,967 RGD:9854643
G Mettl14 methyltransferase like 14 JBrowse link 2 227,566,811 227,583,047 RGD:1624291
G Mettl16 methyltransferase like 16 JBrowse link 10 61,626,595 61,682,947 RGD:1624291
RGD:1600115
G Mettl3 methyltransferase-like 3 JBrowse link 15 28,710,299 28,721,491 RGD:1624291
G Pum1 pumilio RNA-binding family member 1 JBrowse link 5 148,781,239 148,911,776 RGD:1624291
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:1624291
G Rida reactive intermediate imine deaminase A homolog JBrowse link 7 73,256,506 73,270,308 RGD:1600115
RGD:1624291
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1600115
RGD:1624291
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:1624291
G Ythdf2 YTH N(6)-methyladenosine RNA binding protein 2 JBrowse link 5 150,364,490 150,390,173 RGD:1624291
G Ythdf3 YTH N(6)-methyladenosine RNA binding protein 3 JBrowse link 2 100,677,388 100,711,365 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    biological regulation 13336
      regulation of biological quality 4237
        regulation of RNA stability 111
          RNA destabilization 34
            mRNA destabilization + 31
            tRNA destabilization 0
Path 2
Term Annotations click to browse term
  biological_process 19334
    metabolic process 11555
      cellular metabolic process 10567
        cellular aromatic compound metabolic process 5484
          nucleobase-containing compound metabolic process 5258
            nucleic acid metabolic process 4770
              RNA metabolic process 4282
                RNA catabolic process 254
                  regulation of RNA stability 111
                    RNA destabilization 34
                      mRNA destabilization + 31
                      tRNA destabilization 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.