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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of steroid biosynthetic process
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Accession:GO:0050810 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
Synonyms:exact_synonym: regulation of steroid anabolism;   regulation of steroid biosynthesis;   regulation of steroid formation;   regulation of steroid synthesis;   regulation of steroidogenesis


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regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:2303525
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:1600115
RGD:1624291
G Ddx20 DEAD-box helicase 20 JBrowse link 2 208,144,142 208,154,764 RGD:1624291
G Dhh desert hedgehog signaling molecule JBrowse link 7 140,575,288 140,580,783 RGD:1624291
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 JBrowse link 2 200,615,910 200,633,317 RGD:2303525
G Igfbp7 insulin-like growth factor binding protein 7 JBrowse link 14 33,010,300 33,070,193 RGD:1626541
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:1600071
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 54,734,385 54,738,513 RGD:1357210
G Sf1 splicing factor 1 JBrowse link 1 221,735,512 221,749,216 RGD:1624291
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1624291
RGD:13792537
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:2317173
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of androgen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Malrd1 MAM and LDL receptor class A domain containing 1 JBrowse link 17 82,430,836 83,156,696 RGD:1624291
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
RGD:10059686
G Erlin1 ER lipid raft associated 1 JBrowse link 1 263,810,439 263,845,762 RGD:1624291
G Erlin2 ER lipid raft associated 2 JBrowse link 16 69,179,005 69,195,452 RGD:1624291
G Idi2 isopentenyl-diphosphate delta isomerase 2 JBrowse link 17 63,107,152 63,107,469 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
RGD:1600115
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
negative regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:2316921
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde8b phosphodiesterase 8B JBrowse link 2 24,718,548 24,955,533 RGD:1624291
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkkl1 dickkopf like acrosomal protein 1 JBrowse link 1 101,205,426 101,210,675 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:7243836
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
positive regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:1600115
RGD:1624291
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:1624291
G Stard4 StAR-related lipid transfer domain containing 4 JBrowse link 18 25,982,210 25,997,555 RGD:1624291
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg1 ATP binding cassette subfamily G member 1 JBrowse link 20 9,743,269 9,842,735 RGD:1624291
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:13792517
G Fdps farnesyl diphosphate synthase JBrowse link 2 188,403,595 188,413,219 RGD:2316295
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:1624291
RGD:1600115
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785
G Scp2 sterol carrier protein 2 JBrowse link 5 127,647,934 127,735,703 RGD:9850260
G Sec14l2 SEC14-like lipid binding 2 JBrowse link 14 84,335,594 84,360,354 RGD:727312
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291
positive regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
positive regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:10059648
positive regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:2316120
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:1600115
RGD:13792537
RGD:1624291
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:1624291
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:2311095
G Scp2 sterol carrier protein 2 JBrowse link 5 127,647,934 127,735,703 RGD:8554045
RGD:9999179
positive regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:4888510
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1600072
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1600072
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:1600072
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:1600072
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:4889602
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcn2 chloride voltage-gated channel 2 JBrowse link 11 82,862,664 82,876,165 RGD:1600115
RGD:1624291
G LOC108348101 chloride channel protein 2 JBrowse link 11 83,883,428 83,897,396 RGD:1600115
regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:70534
RGD:1624291
G Fgfr4 fibroblast growth factor receptor 4 JBrowse link 17 9,990,072 10,004,339 RGD:1624291
RGD:13792537
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:1624291
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:1298863
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:632010
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:728935
G Pex2 peroxisomal biogenesis factor 2 JBrowse link 2 98,251,756 98,269,185 RGD:1624291
G Scap SREBF chaperone JBrowse link 8 118,551,869 118,628,650 RGD:1624291
regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) JBrowse link 5 166,994,683 167,030,441 RGD:1624291
regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:1624291
regulation of progesterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgkq diacylglycerol kinase, theta JBrowse link 14 2,069,409 2,083,370 RGD:1624291
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:1600115
RGD:1624291
regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lhcgr luteinizing hormone/choriogonadotropin receptor JBrowse link 6 12,493,182 12,554,482 RGD:1624291
RGD:1600115
regulation of testosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
G Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A JBrowse link 19 880,024 887,144 RGD:1624291
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:7775068

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      regulation of metabolic process 6582
        regulation of biosynthetic process 4016
          regulation of lipid biosynthetic process 186
            regulation of steroid biosynthetic process 79
              negative regulation of steroid biosynthetic process + 24
              positive regulation of steroid biosynthetic process + 27
              regulation of androst-4-ene-3,17-dione biosynthetic process + 0
              regulation of bile acid biosynthetic process + 9
              regulation of estrogen biosynthetic process + 0
              regulation of helvolic acid biosynthetic process + 0
              regulation of progesterone biosynthetic process + 3
              regulation of steroid hormone biosynthetic process + 21
              regulation of sterol biosynthetic process + 20
              regulation of testosterone biosynthetic process + 5
              regulation of vitamin D biosynthetic process + 9
Path 2
Term Annotations click to browse term
  biological_process 19439
    biological regulation 13446
      regulation of biological process 12748
        regulation of metabolic process 6582
          regulation of primary metabolic process 5838
            regulation of lipid metabolic process 375
              regulation of lipid biosynthetic process 186
                regulation of steroid biosynthetic process 79
                  negative regulation of steroid biosynthetic process + 24
                  positive regulation of steroid biosynthetic process + 27
                  regulation of androst-4-ene-3,17-dione biosynthetic process + 0
                  regulation of bile acid biosynthetic process + 9
                  regulation of estrogen biosynthetic process + 0
                  regulation of helvolic acid biosynthetic process + 0
                  regulation of progesterone biosynthetic process + 3
                  regulation of steroid hormone biosynthetic process + 21
                  regulation of sterol biosynthetic process + 20
                  regulation of testosterone biosynthetic process + 5
                  regulation of vitamin D biosynthetic process + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.