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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of calcium-mediated signaling
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Accession:GO:0050849 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
Synonyms:exact_synonym: down regulation of calcium-mediated signaling;   downregulation of calcium-mediated signaling;   negative regulation of calcium-mediated signalling
 narrow_synonym: inhibition of calcium-mediated signaling


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negative regulation of calcium-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd22 CD22 molecule JBrowse link 1 89,313,475 89,329,902 RGD:1624291
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 JBrowse link 4 140,247,297 140,580,749 RGD:1624291
RGD:1600115
G Siglec10 sialic acid binding Ig-like lectin 10 JBrowse link 1 98,512,663 98,521,736 RGD:1624291
G Sla2 Src-like-adaptor 2 JBrowse link 3 152,942,838 153,004,047 RGD:1624291
negative regulation of calcineurin-NFAT signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:1624291
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:10047333
RGD:1624291
G Chp1 calcineurin-like EF-hand protein 1 JBrowse link 3 111,354,506 111,389,998 RGD:1624291
RGD:1600115
G Cmya5 cardiomyopathy associated 5 JBrowse link 2 22,646,694 22,744,536 RGD:1624291
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 JBrowse link 7 61,785,423 61,816,775 RGD:1624291
G Fhl2 four and a half LIM domains 2 JBrowse link 9 49,920,611 49,994,906 RGD:13601990
RGD:13792537
RGD:1624291
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:1600115
RGD:1624291
G Homer2 homer scaffold protein 2 JBrowse link 1 143,443,300 143,535,579 RGD:1600115
RGD:1624291
G Homer3 homer scaffold protein 3 JBrowse link 16 20,880,447 20,890,968 RGD:1600115
RGD:1624291
G Mapk7 mitogen-activated protein kinase 7 JBrowse link 10 47,768,592 47,775,130 RGD:1624291
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
G Myoz1 myozenin 1 JBrowse link 15 4,077,066 4,084,306 RGD:1624291
G Myoz2 myozenin 2 JBrowse link 2 227,180,887 227,207,629 RGD:1624291
G Prnp prion protein JBrowse link 3 124,515,917 124,531,320 RGD:1624291
G Rcan1 regulator of calcineurin 1 JBrowse link 11 32,539,689 32,620,274 RGD:1600115
RGD:1624291
G Tbc1d10c TBC1 domain family, member 10C JBrowse link 1 219,431,094 219,439,102 RGD:1624291
negative regulation of CAMKK-AMPK signaling cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egln1 egl-9 family hypoxia-inducible factor 1 JBrowse link 19 57,660,194 57,701,158 RGD:11340206
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1624291
RGD:1600115
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1600115
RGD:1624291
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1624291
RGD:1600115
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:1624291
RGD:1600115
RGD:2314601
G Clic2 chloride intracellular channel 2 JBrowse link 20 295,338 310,363 RGD:1624291
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
RGD:1600115
G Gstm7 glutathione S-transferase, mu 7 JBrowse link 2 210,720,719 210,726,179 RGD:1600115
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1624291
RGD:1600115
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      negative regulation of signaling 1396
        negative regulation of signal transduction 1232
          negative regulation of intracellular signal transduction 546
            negative regulation of calcium-mediated signaling 33
              negative regulation of CAMKK-AMPK signaling cascade 1
              negative regulation of calcineurin-mediated signaling + 16
              negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
              negative regulation of ryanodine-sensitive calcium-release channel activity 12
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            intracellular signal transduction 2597
              second-messenger-mediated signaling 481
                calcium-mediated signaling 233
                  regulation of calcium-mediated signaling 109
                    negative regulation of calcium-mediated signaling 33
                      negative regulation of CAMKK-AMPK signaling cascade 1
                      negative regulation of calcineurin-mediated signaling + 16
                      negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
                      negative regulation of ryanodine-sensitive calcium-release channel activity 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.