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Term:B cell receptor signaling pathway
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Accession:GO:0050853 term browser browse the term
Definition:A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
Synonyms:exact_synonym: B cell receptor signalling pathway;   B lymphocyte receptor signaling pathway;   B lymphocyte receptor signalling pathway


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B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034739.1 Ig lambda-2 chain C region RGD:13792537
G AABR07065640.1 RGD:13792537
G AABR07065643.1 RGD:13792537
G AABR07065645.1 RGD:13792537
G AABR07065645.2 RGD:13792537
G AABR07065651.1 RGD:13792537
G AABR07065651.2 RGD:13792537
G AABR07065651.3 RGD:13792537
G AABR07065651.4 RGD:13792537
G AABR07065651.5 RGD:13792537
G AABR07065651.6 RGD:13792537
G AABR07065651.7 RGD:13792537
G AABR07065651.8 RGD:13792537
G AABR07065656.1 RGD:13792537
G AABR07065656.10 RGD:13792537
G AABR07065656.2 RGD:13792537
G AABR07065656.3 RGD:13792537
G AABR07065656.4 RGD:13792537
G AABR07065656.5 RGD:13792537
G AABR07065656.6 RGD:13792537
G AABR07065656.7 RGD:13792537
G AABR07065656.8 RGD:13792537
G AABR07065656.9 RGD:13792537
G AABR07065673.1 RGD:13792537
G AABR07065676.1 RGD:13792537
G AABR07065680.1 RGD:13792537
G AABR07065684.1 RGD:13792537
G AABR07065688.1 RGD:13792537
G AABR07065693.1 RGD:13792537
G AABR07065693.2 RGD:13792537
G AABR07065693.3 RGD:13792537
G AABR07065699.1 RGD:13792537
G AABR07065699.2 RGD:13792537
G AABR07065699.3 RGD:13792537
G AABR07065699.4 RGD:13792537
G AABR07065699.5 RGD:13792537
G AABR07065705.1 RGD:13792537
G AABR07065705.4 RGD:13792537
G AABR07065705.5 RGD:13792537
G AABR07065705.6 RGD:13792537
G AABR07065714.1 RGD:13792537
G AABR07065737.1 RGD:13792537
G AABR07065740.1 RGD:13792537
G AABR07065750.1 RGD:13792537
G AABR07065750.2 RGD:13792537
G AABR07065753.1 RGD:13792537
G AABR07065768.1 RGD:13792537
G AABR07065768.2 RGD:13792537
G AABR07065768.3 RGD:13792537
G AABR07065772.1 RGD:13792537
G AABR07065772.2 RGD:13792537
G AABR07065772.4 RGD:13792537
G AABR07065773.1 RGD:13792537
G AABR07065774.1 RGD:13792537
G AABR07065776.2 RGD:13792537
G AABR07065776.3 RGD:13792537
G AABR07065778.1 RGD:13792537
G AABR07065778.2 RGD:13792537
G AABR07065778.3 RGD:13792537
G AABR07065781.1 RGD:13792537
G AABR07065782.1 RGD:13792537
G AABR07065789.1 RGD:13792537
G AABR07065789.2 RGD:13792537
G AABR07065789.3 RGD:13792537
G AABR07065790.1 RGD:13792537
G AABR07065792.1 RGD:13792537
G AABR07065792.2 RGD:13792537
G AABR07065798.1 RGD:13792537
G AABR07065802.1 RGD:13792537
G AABR07065804.1 RGD:13792537
G AABR07065808.1 RGD:13792537
G AABR07065811.1 RGD:13792537
G AABR07065812.1 RGD:13792537
G AABR07065812.2 RGD:13792537
G AABR07065813.1 RGD:13792537
G AABR07065814.1 RGD:13792537
G AABR07065814.2 RGD:13792537
G AABR07065814.3 RGD:13792537
G AABR07065814.4 RGD:13792537
G AABR07065814.5 RGD:13792537
G AABR07065814.7 RGD:13792537
G AABR07065815.1 RGD:13792537
G AABR07065815.2 RGD:13792537
G AABR07065821.1 RGD:13792537
G AABR07065823.1 RGD:13792537
G AABR07065823.2 RGD:13792537
G AABR07065823.3 RGD:13792537
G AABR07065827.1 RGD:13792537
G AABR07065834.1 RGD:13792537
G AABR07065837.1 RGD:13792537
G AABR07065839.1 RGD:13792537
G AABR07065844.1 RGD:13792537
G AABR07065877.1 RGD:13792537
G AABR07065883.1 RGD:13792537
G AABR07065886.1 RGD:13792537
G AABR07065889.1 RGD:13792537
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G AC109737.1 RGD:13792537
G Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link 19 43,932,543 43,967,452 RGD:1600115
RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1600115
RGD:1624291
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:1624291
G Blnk B-cell linker JBrowse link 1 260,187,023 260,254,490 RGD:1624291
G Bmx BMX non-receptor tyrosine kinase JBrowse link X 31,976,231 32,046,326 RGD:13792537
G Cd19 CD19 molecule JBrowse link 1 197,815,422 197,822,123 RGD:13792537
RGD:1624291
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:1624291
G Cd79a CD79a molecule JBrowse link 1 81,763,609 81,768,039 RGD:1624291
RGD:13792537
G Cd79al Cd79a molecule-like JBrowse link 9 16,793,811 16,795,994 RGD:13792537
G Cd79b CD79b molecule JBrowse link 10 94,497,445 94,500,591 RGD:1624291
RGD:13792537
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:1624291
RGD:13792537
G IgG-2a gamma-2a immunoglobulin heavy chain RGD:13792537
G Igh-6 immunoglobulin heavy chain 6 RGD:13792537
G Ighe immunoglobulin heavy constant epsilon JBrowse link 6 138,066,728 138,068,606 RGD:13792537
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:13792537
G Ighm immunoglobulin heavy constant mu RGD:13792537
G Igkc immunoglobulin kappa constant RGD:13792537
G Igll1 immunoglobulin lambda-like polypeptide 1 JBrowse link 11 88,388,378 88,391,524 RGD:13792537
G Itk IL2-inducible T-cell kinase JBrowse link 10 31,431,820 31,493,413 RGD:13792537
G Klhl6 kelch-like family member 6 JBrowse link 11 84,745,958 84,785,315 RGD:1624291
G Lat2 linker for activation of T cells family, member 2 JBrowse link 12 25,114,099 25,128,381 RGD:1624291
RGD:1600115
G Lck LCK proto-oncogene, Src family tyrosine kinase JBrowse link 5 147,750,976 147,779,627 RGD:1624291
RGD:13792537
G Lime1 Lck interacting transmembrane adaptor 1 JBrowse link 3 176,881,881 176,888,230 RGD:1624291
RGD:13792537
G LOC100359530 rCG21044-like JBrowse link 6 138,930,894 138,931,525 RGD:13792537
G LOC100359684 mCG114411-like JBrowse link 6 140,406,777 140,407,357 RGD:13792537
G LOC100360344 hypothetical protein LOC100360344 JBrowse link 6 139,292,970 139,293,665 RGD:13792537
G LOC100360436 hypothetical LOC100360436 JBrowse link 6 139,345,463 139,346,007 RGD:13792537
G LOC100360761 rCG64219-like JBrowse link 6 140,979,689 140,980,243 RGD:13792537
G LOC100361105 Igh protein-like JBrowse link 6 141,146,691 141,147,268 RGD:13792537
G LOC100361706 lambda-chain C1-region-like JBrowse link 11 86,094,822 86,096,399 RGD:13792537
G LOC100361945 mCG129376-like JBrowse link 6 139,486,687 139,487,301 RGD:13792537
G LOC100365649 hypothetical LOC100365649 JBrowse link 6 138,743,974 138,744,542 RGD:13792537
G LOC100911906 uncharacterized LOC100911906 JBrowse link 6 138,954,101 138,954,839 RGD:13792537
G LOC362795 immunoglobulin G heavy chain JBrowse link 6 138,192,156 138,201,560 RGD:13792537
G LOC691815 Ig heavy chain V region PJ14-like JBrowse link 6 140,714,720 140,715,176 RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Mnda myeloid cell nuclear differentiation antigen JBrowse link 13 92,073,664 92,091,335 RGD:1624291
G Ms4a1 membrane spanning 4-domains A1 JBrowse link 1 227,429,241 227,441,492 RGD:1624291
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G Nfam1 NFAT activating protein with ITAM motif 1 JBrowse link 7 123,856,718 123,893,790 RGD:1624291
G Nfatc2 nuclear factor of activated T-cells 2 JBrowse link 3 165,241,750 165,374,644 RGD:1624291
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:1600115
RGD:1624291
G Plekha1 pleckstrin homology domain containing A1 JBrowse link 1 201,429,716 201,481,411 RGD:1624291
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:1600115
RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1600115
RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1600115
RGD:1624291
G Rftn1 raftlin lipid raft linker 1 JBrowse link 9 12,740,885 12,942,358 RGD:1624291
G RGD1564318 similar to immunoglobulin light chain variable region RGD:13792537
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:13792537
RGD:1624291
G Tec tec protein tyrosine kinase JBrowse link 14 37,918,884 38,027,953 RGD:1624291
RGD:13792537
G Vav3 vav guanine nucleotide exchange factor 3 JBrowse link 2 212,247,061 212,585,818 RGD:1624291
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd22 CD22 molecule JBrowse link 1 89,313,475 89,329,902 RGD:1624291
RGD:13792537
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Fcrl5 Fc receptor-like 5 JBrowse link 2 186,776,466 186,797,900 RGD:1624291
G Gps2 G protein pathway suppressor 2 JBrowse link 10 56,524,327 56,527,447 RGD:1624291
G Lpxn leupaxin JBrowse link 1 229,642,437 229,674,129 RGD:1624291
RGD:13792537
G Plcl2 phospholipase C-like 2 JBrowse link 9 1,782,536 1,984,654 RGD:1624291
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 JBrowse link 19 830,874 838,528 RGD:1624291
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Nfam1 NFAT activating protein with ITAM motif 1 JBrowse link 7 123,856,718 123,893,790 RGD:1624291
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:1600115
RGD:1624291
G Prkch protein kinase C, eta JBrowse link 6 96,479,243 96,677,368 RGD:1624291
RGD:1600115
G Slc39a10 solute carrier family 39 member 10 JBrowse link 9 59,947,562 60,070,549 RGD:1624291
RGD:13792537
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
regulation of B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:13792537
G Cd19 CD19 molecule JBrowse link 1 197,815,422 197,822,123 RGD:1624291
G Gcsam germinal center-associated, signaling and motility JBrowse link 11 60,168,938 60,180,191 RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    immune system process 2798
      activation of immune response 418
        immune response-activating signal transduction 320
          immune response-activating cell surface receptor signaling pathway 319
            antigen receptor-mediated signaling pathway 285
              B cell receptor signaling pathway 167
                B cell receptor apoptotic signaling pathway 1
                negative regulation of B cell receptor signaling pathway 7
                positive regulation of B cell receptor signaling pathway 8
                regulation of B cell receptor signaling pathway + 19
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        positive regulation of biological process 6625
          positive regulation of immune system process 1060
            positive regulation of immune response 672
              activation of immune response 418
                immune response-activating signal transduction 320
                  immune response-activating cell surface receptor signaling pathway 319
                    antigen receptor-mediated signaling pathway 285
                      B cell receptor signaling pathway 167
                        B cell receptor apoptotic signaling pathway 1
                        negative regulation of B cell receptor signaling pathway 7
                        positive regulation of B cell receptor signaling pathway 8
                        regulation of B cell receptor signaling pathway + 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.