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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of antigen receptor-mediated signaling pathway
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Accession:GO:0050857 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
Synonyms:exact_synonym: positive regulation of antigen receptor mediated signalling pathway;   up regulation of antigen receptor-mediated signaling pathway;   upregulation of antigen receptor-mediated signaling pathway
 narrow_synonym: activation of antigen receptor-mediated signaling pathway;   stimulation of antigen receptor-mediated signaling pathway


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positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase, receptor type, C ISO
ISS
(MGI:MGI:3687418|PMID:8692271)
GO_REF:0000024
RGD
UniProt
PMID:8692271 GO_REF:0000024, MGI:MGI:3687418 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:5476553|PMID:23499492)
(PMID:20237408)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20237408, PMID:23499492 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5476553 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 ISO (MGI:MGI:3047050|PMID:15196959) RGD PMID:15196959 MGI:MGI:3047050 NCBI chr19:830,874...838,528
Ensembl chr19:830,877...838,099
JBrowse link
G Foxp1 forkhead box P1 ISO (PMID:30111844) RGD PMID:30111844 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 ISO (MGI:MGI:3044463|PMID:15143214) RGD PMID:15143214 MGI:MGI:3044463 NCBI chr 7:123,856,718...123,893,790
Ensembl chr 7:123,856,567...123,892,429
JBrowse link
G Prkcb protein kinase C, beta IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3700457|PMID:16301747)
Ensembl
UniProt
RGD
PMID:16301747 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3700457 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkch protein kinase C, eta ISO
ISS
(PMID:18780722)
GO_REF:0000024
RGD
UniProt
PMID:18780722 GO_REF:0000024 NCBI chr 6:96,479,243...96,677,368
Ensembl chr 6:96,479,430...96,676,225
JBrowse link
G Slc39a10 solute carrier family 39 member 10 ISO
IBA
MGI:MGI:5642299 (MGI:MGI:5586914|PMID:25074919)
PMID:21873635
RGD PMID:25074919, PMID:21873635 MGI:MGI:5586914, RGD:13792537 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Stap1 signal transducing adaptor family member 1 ISO (PMID:10518561) RGD PMID:10518561 NCBI chr14:23,575,400...23,604,984
Ensembl chr14:23,576,085...23,604,834
JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07032888.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr18:87,415,531...87,415,884 JBrowse link
G Ada adenosine deaminase ISO MGI:MGI:1857117|MGI:MGI:2683027 (MGI:MGI:3640996|PMID:11435465) RGD PMID:11435465 MGI:MGI:3640996 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Card11 caspase recruitment domain family, member 11 ISO (PMID:12154360) RGD PMID:12154360 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO (MGI:MGI:3847607|PMID:17785582) RGD PMID:17785582 MGI:MGI:3847607 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Cd226 CD226 molecule ISO
IBA
(PMID:26755705)
PMID:21873635
RGD PMID:26755705, PMID:21873635 RGD:13792537 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765
JBrowse link
G Cd81 Cd81 molecule ISS
ISO
IEA
GO_REF:0000024
(PMID:23858057)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23858057 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase ISO
IEA
MGI:MGI:3664438 (MGI:MGI:3656194|PMID:16501569)
GO_REF:0000107
RGD
Ensembl
PMID:16501569 GO_REF:0000107, MGI:MGI:3656194 NCBI chr19:19,264,984...19,323,817
Ensembl chr19:19,265,164...19,315,357
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ISO
IEA
(PMID:18796614)
GO_REF:0000107
RGD
Ensembl
PMID:18796614 GO_REF:0000107 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 ISO
IBA
(PMID:26755705)
PMID:21873635
RGD PMID:26755705, PMID:21873635 RGD:13792537 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585
JBrowse link
G Prkd2 protein kinase D2 ISO
ISS
(MGI:MGI:4849903|PMID:20819079)
GO_REF:0000024
RGD
UniProt
PMID:20819079 GO_REF:0000024, MGI:MGI:4849903 NCBI chr 1:78,767,911...78,796,223
Ensembl chr 1:78,767,911...78,796,231
JBrowse link
G Rab29 RAB29, member RAS oncogene family ISO (PMID:26021297) RGD PMID:26021297 NCBI chr13:48,644,575...48,650,229
Ensembl chr13:48,644,604...48,650,220
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rps3 ribosomal protein S3 ISO (PMID:18045535) RGD PMID:18045535 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 ISO (PMID:11390434) RGD PMID:11390434 NCBI chr11:54,619,169...54,661,284
Ensembl chr11:54,619,129...54,662,353
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      signal transduction 7011
        positive regulation of signal transduction 1604
          positive regulation of antigen receptor-mediated signaling pathway 22
            positive regulation of B cell receptor signaling pathway 8
            positive regulation of T cell receptor signaling pathway 14
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological process 13075
        regulation of immune system process 1481
          positive regulation of immune system process 1015
            positive regulation of immune response 655
              activation of immune response 418
                immune response-activating signal transduction 319
                  immune response-activating cell surface receptor signaling pathway 318
                    antigen receptor-mediated signaling pathway 284
                      regulation of antigen receptor-mediated signaling pathway 65
                        positive regulation of antigen receptor-mediated signaling pathway 22
                          positive regulation of B cell receptor signaling pathway 8
                          positive regulation of T cell receptor signaling pathway 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.