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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of B cell activation
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Accession:GO:0050869 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
Synonyms:exact_synonym: down regulation of B cell activation;   downregulation of B cell activation;   negative regulation of B lymphocyte activation
 narrow_synonym: inhibition of B cell activation


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negative regulation of B cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bank1 B-cell scaffold protein with ankyrin repeats 1 JBrowse link 2 241,273,763 241,545,527 RGD:1624291
RGD:13792537
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 JBrowse link 11 14,252,088 14,405,825 RGD:1624291
RGD:13792537
G Tbc1d10c TBC1 domain family, member 10C JBrowse link 1 219,431,094 219,439,102 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
negative regulation of B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt3 Fms related receptor tyrosine kinase 3 JBrowse link 12 9,360,439 9,437,004 RGD:1624291
G Hmgb3 high mobility group box 3 JBrowse link 17 36,690,190 36,694,329 RGD:1624291
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1600115
RGD:1624291
negative regulation of B cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:1624291
G Btla B and T lymphocyte associated JBrowse link 11 60,523,692 60,547,234 RGD:1624291
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:1624291
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1624291
RGD:1600115
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
RGD:1600115
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
G Mnda myeloid cell nuclear differentiation antigen JBrowse link 13 92,073,664 92,091,335 RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:1624291
RGD:1600115
G Pkn1 protein kinase N1 JBrowse link 19 24,803,524 24,832,305 RGD:1624291
G Prdm1 PR/SET domain 1 JBrowse link 20 49,464,921 49,556,623 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Tnfrsf13b TNF receptor superfamily member 13B JBrowse link 10 47,399,834 47,422,907 RGD:1624291
RGD:13792537
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:1624291
RGD:13792537
RGD:1600115
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    negative regulation of biological process 5578
      negative regulation of immune system process 472
        negative regulation of leukocyte activation 195
          negative regulation of lymphocyte activation 164
            negative regulation of B cell activation 36
              negative regulation of B cell differentiation + 4
              negative regulation of B cell proliferation 20
              negative regulation of isotype switching + 6
Path 2
Term Annotations click to browse term
  biological_process 19439
    biological regulation 13446
      regulation of biological process 12748
        regulation of cellular process 12248
          regulation of cell activation 696
            regulation of leukocyte activation 653
              negative regulation of leukocyte activation 195
                negative regulation of lymphocyte activation 164
                  negative regulation of B cell activation 36
                    negative regulation of B cell differentiation + 4
                    negative regulation of B cell proliferation 20
                    negative regulation of isotype switching + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.