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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chemotaxis
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Accession:GO:0050922 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
Synonyms:exact_synonym: down regulation of chemotaxis;   downregulation of chemotaxis
 narrow_synonym: inhibition of chemotaxis


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negative regulation of chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp3 dual specificity phosphatase 3 ISO (PMID:28759036) RGD PMID:28759036 NCBI chr10:89,904,578...89,918,296
Ensembl chr10:89,904,560...89,918,427
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO
ISS
(MGI:MGI:3029644|PMID:14966296)
GO_REF:0000024
RGD
UniProt
PMID:14966296 GO_REF:0000024, MGI:MGI:3029644 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 IDA RGD PMID:11559557 RGD:10043143 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422
JBrowse link
negative regulation of axon extension involved in axon guidance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 IMP RGD PMID:19884510 RGD:9681717 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Nrp1 neuropilin 1 IMP
ISO
(MGI:MGI:1289520|PMID:9753685) RGD PMID:9753685, PMID:9288754 MGI:MGI:1289520, RGD:633436 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Plxna3 plexin A3 ISO MGI:MGI:107558|MGI:MGI:1096347 (MGI:MGI:2152659|PMID:11683995) RGD PMID:11683995 MGI:MGI:2152659 NCBI chr  X:156,363,400...156,379,433
Ensembl chr  X:156,363,405...156,379,189
JBrowse link
G Ryk receptor-like tyrosine kinase ISO MGI:MGI:98958 (MGI:MGI:3625635|PMID:16723543) RGD PMID:16723543 MGI:MGI:3625635 NCBI chr 8:111,326,339...111,398,640
Ensembl chr 8:111,326,433...111,397,867
JBrowse link
G Sema3a semaphorin 3A ISO
IBA
MGI:MGI:104518|MGI:MGI:107683|MGI:MGI:96721 (MGI:MGI:1289520|PMID:9753685), (MGI:MGI:2152659|PMID:11683995), (MGI:MGI:3801368|PMID:18550718), (MGI:MGI:73216|PMID:7748561)
PMID:21873635
RGD PMID:7748561, PMID:9753685, PMID:11683995, PMID:18550718, PMID:21873635 MGI:MGI:1289520, MGI:MGI:2152659, MGI:MGI:3801368, MGI:MGI:73216, RGD:13792537 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Sema3b semaphorin 3B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:116,353,791...116,362,655
Ensembl chr 8:116,354,073...116,361,343
JBrowse link
G Sema3c semaphorin 3C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
G Sema3d semaphorin 3D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:19,224,378...19,413,519
Ensembl chr 4:19,224,310...19,413,484
JBrowse link
G Sema3e semaphorin 3E IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:17,314,745...17,594,659
Ensembl chr 4:17,272,511...17,594,598
JBrowse link
G Sema3f semaphorin 3F ISO
IBA
MGI:MGI:107683 (MGI:MGI:1289520|PMID:9753685), (MGI:MGI:2152659|PMID:11683995)
PMID:21873635
RGD PMID:9753685, PMID:11683995, PMID:21873635 MGI:MGI:1289520, MGI:MGI:2152659, RGD:13792537 NCBI chr 8:116,439,996...116,469,915
Ensembl chr 8:116,437,696...116,469,915
JBrowse link
G Sema3g semaphorin 3G IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:7,303,582...7,315,214
Ensembl chr16:7,303,578...7,315,390
JBrowse link
G Sema4a semaphorin 4A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:187,799,568...187,823,014
Ensembl chr 2:187,799,568...187,822,997
JBrowse link
G Sema4b semaphorin 4B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:141,986,145...142,014,400
Ensembl chr 1:141,986,145...142,014,398
JBrowse link
G Sema4c semaphorin 4C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:43,129,413...43,140,442
Ensembl chr 9:43,129,415...43,139,870
JBrowse link
G Sema4d semaphorin 4D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:13,516,276...13,538,513
Ensembl chr17:13,488,376...13,553,974
JBrowse link
G Sema4f ssemaphorin 4F IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:113,738,225...113,764,532
Ensembl chr 4:113,738,226...113,764,532
JBrowse link
G Sema4g semaphorin 4G IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:264,738,935...264,753,399
Ensembl chr 1:264,741,911...264,753,397
JBrowse link
G Sema5a semaphorin 5A IMP
IBA
PMID:15603739
PMID:21873635
UniProt
GO_Central
PMID:15603739, PMID:21873635 RGD:8553809, RGD:13792537 NCBI chr 2:85,377,318...85,808,970
Ensembl chr 2:85,377,318...85,808,970
JBrowse link
G Sema5b semaphorin 5B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:68,304,844...68,435,109
Ensembl chr11:68,306,659...68,349,238
JBrowse link
G Sema6a semaphorin 6A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:41,330,519...41,451,813
Ensembl chr18:41,333,551...41,389,510
JBrowse link
G Sema6b semaphorin 6B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:10,934,273...10,951,252
Ensembl chr 9:10,941,613...10,951,252
JBrowse link
G Sema6c semaphorin 6C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:196,330,777...196,347,218
Ensembl chr 2:196,334,626...196,344,008
JBrowse link
G Sema6d semaphorin 6D IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:116,899,906...116,958,059
Ensembl chr 3:116,899,878...116,958,050
JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:62,723,788...62,746,530
Ensembl chr 8:62,723,788...62,745,868
JBrowse link
G Slit1 slit guidance ligand 1 IDA RGD PMID:15632296 RGD:1358459 NCBI chr 1:260,843,481...260,992,366
Ensembl chr 1:260,843,483...260,992,366
JBrowse link
G Wnt3 Wnt family member 3 ISO (MGI:MGI:3806438|PMID:18716223) RGD PMID:18716223 MGI:MGI:3806438 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
G Wnt3a Wnt family member 3A ISO (MGI:MGI:3806438|PMID:18716223) RGD PMID:18716223 MGI:MGI:3806438 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Wnt5a Wnt family member 5A ISO
IEA
MGI:MGI:101766 (MGI:MGI:3625635|PMID:16723543)
GO_REF:0000107
RGD
Ensembl
PMID:16723543 GO_REF:0000107, MGI:MGI:3625635 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
negative regulation of dendritic cell chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slamf8 SLAM family member 8 ISO MGI:MGI:5442794 (MGI:MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:MGI:5752697 NCBI chr13:90,967,862...90,978,752
Ensembl chr13:90,967,739...90,977,734
JBrowse link
negative regulation of endothelial cell chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hrg histidine-rich glycoprotein IEA
ISO
ISS
GO_REF:0000107
(PMID:14744774), (PMID:16436387), (PMID:16489009)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:14744774, PMID:16436387, PMID:16489009 GO_REF:0000024, GO_REF:0000107 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein ISS GO_REF:0000024 UniProt GO_REF:0000024 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Notch1 notch receptor 1 ISO
ISS
(PMID:20616313)
GO_REF:0000024
RGD
UniProt
PMID:20616313 GO_REF:0000024 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:16150726) RGD PMID:16150726 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
negative regulation of endothelial cell chemotaxis to fibroblast growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl13 C-X-C motif chemokine ligand 13 ISO (PMID:11708770) RGD PMID:11708770 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
negative regulation of leukocyte chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr18 G protein-coupled receptor 18 ISO MGI:MGI:5708707 (MGI:MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:MGI:5629467 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist IDA RGD PMID:15528323 RGD:2303400 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Slit2 slit guidance ligand 2 ISO (PMID:11309622) RGD PMID:11309622 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
negative regulation of lymphocyte chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Padi2 peptidyl arginine deiminase 2 IEA
ISO
GO_REF:0000107
(PMID:18645041)
Ensembl
RGD
PMID:18645041 GO_REF:0000107 NCBI chr 5:159,428,479...159,471,113
Ensembl chr 5:159,428,515...159,471,144
JBrowse link
negative regulation of macrophage chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5 complement C5 ISO
IEA
(PMID:14566334)
GO_REF:0000107
RGD
Ensembl
PMID:14566334 GO_REF:0000107 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO
IEA
MGI:MGI:1857043 (MGI:MGI:5610078|PMID:25447050)
GO_REF:0000107
RGD
Ensembl
PMID:25447050 GO_REF:0000107, MGI:MGI:5610078 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Ddt D-dopachrome tautomerase ISO (PMID:21817065) RGD PMID:21817065 NCBI chr20:13,827,153...13,829,624
Ensembl chr20:13,827,132...13,831,588
JBrowse link
G Mif macrophage migration inhibitory factor ISO (PMID:21817065) RGD PMID:21817065 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mmp28 matrix metallopeptidase 28 ISO MGI:MGI:3836773 (MGI:MGI:3836320|PMID:19265166) RGD PMID:19265166 MGI:MGI:3836320 NCBI chr10:70,660,691...70,681,672
Ensembl chr10:70,660,691...70,681,672
JBrowse link
G Slamf8 SLAM family member 8 ISO MGI:MGI:5442794 (MGI:MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:MGI:5752697 NCBI chr13:90,967,862...90,978,752
Ensembl chr13:90,967,739...90,977,734
JBrowse link
G Stap1 signal transducing adaptor family member 1 ISO (MGI:MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:MGI:3831067 NCBI chr14:23,575,400...23,604,984
Ensembl chr14:23,576,085...23,604,834
JBrowse link
negative regulation of mast cell chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rin3 Ras and Rab interactor 3 ISO (PMID:23185384) RGD PMID:23185384 NCBI chr 6:126,170,672...126,279,682
Ensembl chr 6:126,170,720...126,279,682
JBrowse link
negative regulation of monocyte chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn3 cellular communication network factor 3 ISO
ISS
(PMID:21063504)
GO_REF:0000024
RGD
UniProt
PMID:21063504 GO_REF:0000024 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO (PMID:22991462) RGD PMID:22991462 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist IDA PMID:15528323 BHF-UCL PMID:15528323 RGD:2303400 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Nbl1 NBL1, DAN family BMP antagonist ISO
IEA
(MGI:MGI:5318030|PMID:15528323)
GO_REF:0000107
RGD
Ensembl
PMID:15528323 GO_REF:0000107, MGI:MGI:5318030 NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
JBrowse link
G Slamf8 SLAM family member 8 ISO MGI:MGI:5442794 (MGI:MGI:5752697|PMID:25799045) RGD PMID:25799045 MGI:MGI:5752697 NCBI chr13:90,967,862...90,978,752
Ensembl chr13:90,967,739...90,977,734
JBrowse link
G Slit2 slit guidance ligand 2 IDA PMID:15528323 BHF-UCL PMID:15528323 RGD:2303400 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
negative regulation of natural killer cell chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO (PMID:7545673) RGD PMID:7545673 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Klre1 killer cell lectin-like receptor, family E, member 1 ISO (PMID:22585739) RGD PMID:22585739 NCBI chr 4:163,346,684...163,355,050
Ensembl chr 4:163,349,125...163,354,976
JBrowse link
G Klrk1 killer cell lectin like receptor K1 ISO
IEA
(PMID:22585739)
GO_REF:0000107
RGD
Ensembl
PMID:22585739 GO_REF:0000107 NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
JBrowse link
negative regulation of negative chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Robo1 roundabout guidance receptor 1 IEA
ISO
GO_REF:0000107
(PMID:11748139)
Ensembl
RGD
PMID:11748139 GO_REF:0000107 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO (PMID:11748139) RGD PMID:11748139 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
negative regulation of neutrophil chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C5ar2 complement component 5a receptor 2 ISO
ISS
(PMID:16204243)
GO_REF:0000024
RGD
UniProt
PMID:16204243 GO_REF:0000024 NCBI chr 1:78,165,155...78,183,426
Ensembl chr 1:78,166,810...78,180,216
JBrowse link
G Dpp4 dipeptidylpeptidase 4 ISO (PMID:23677473) RGD PMID:23677473 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Slit2 slit guidance ligand 2 IEA
ISO
GO_REF:0000107
(PMID:19759280)
Ensembl
RGD
PMID:19759280 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
negative regulation of positive chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt2 angiopoietin 2 ISO (PMID:9660821) RGD PMID:9660821 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
negative regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slit2 slit guidance ligand 2 IEA
ISO
GO_REF:0000107
(PMID:17062560)
Ensembl
RGD
PMID:17062560 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
negative regulation of smooth muscle cell chemotaxis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 ISO (PMID:22116621) RGD PMID:22116621 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Coro1b coronin 1B IMP
IEA
ISO
PMID:22619279
GO_REF:0000107
(PMID:22619279)
Ensembl
RGD
PMID:22619279, PMID:22619279 GO_REF:0000107, RGD:10047170 NCBI chr 1:219,397,827...219,403,253
Ensembl chr 1:219,397,850...219,403,260
JBrowse link
G Gstp1 glutathione S-transferase pi 1 IMP RGD PMID:24321768 RGD:10401938 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Slit2 slit guidance ligand 2 ISO
IEA
(PMID:16439689)
GO_REF:0000107
RGD
Ensembl
PMID:16439689 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    locomotion 1951
      negative regulation of locomotion 349
        negative regulation of chemotaxis 62
          negative regulation of Schwann cell chemotaxis 0
          negative regulation of astrocyte chemotaxis 0
          negative regulation of axon extension involved in axon guidance 28
          negative regulation of axon guidance + 1
          negative regulation of cell chemotaxis to fibroblast growth factor + 1
          negative regulation of chemokine activity 0
          negative regulation of chemotaxis to arachidonic acid 0
          negative regulation of endothelial cell chemotaxis + 5
          negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
          negative regulation of fibroblast chemotaxis 0
          negative regulation of leukocyte chemotaxis + 20
          negative regulation of muscle cell chemotaxis toward tendon cell 0
          negative regulation of negative chemotaxis + 2
          negative regulation of positive chemotaxis + 1
          negative regulation of smooth muscle cell chemotaxis 4
Path 2
Term Annotations click to browse term
  biological_process 20028
    biological regulation 13773
      regulation of biological process 13075
        regulation of response to stimulus 3981
          regulation of response to external stimulus 953
            regulation of chemotaxis 241
              negative regulation of chemotaxis 62
                negative regulation of Schwann cell chemotaxis 0
                negative regulation of astrocyte chemotaxis 0
                negative regulation of axon extension involved in axon guidance 28
                negative regulation of axon guidance + 1
                negative regulation of cell chemotaxis to fibroblast growth factor + 1
                negative regulation of chemokine activity 0
                negative regulation of chemotaxis to arachidonic acid 0
                negative regulation of endothelial cell chemotaxis + 5
                negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
                negative regulation of fibroblast chemotaxis 0
                negative regulation of leukocyte chemotaxis + 20
                negative regulation of muscle cell chemotaxis toward tendon cell 0
                negative regulation of negative chemotaxis + 2
                negative regulation of positive chemotaxis + 1
                negative regulation of smooth muscle cell chemotaxis 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.