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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chemotaxis
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Accession:GO:0050922 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
Synonyms:exact_synonym: down regulation of chemotaxis;   downregulation of chemotaxis
 narrow_synonym: inhibition of chemotaxis


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negative regulation of chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dusp3 dual specificity phosphatase 3 JBrowse link 10 89,904,578 89,918,296 RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 JBrowse link 11 80,927,601 80,981,424 RGD:10043143
negative regulation of axon extension involved in axon guidance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:9681717
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:633436
RGD:1624291
G Plxna3 plexin A3 JBrowse link X 156,363,400 156,379,433 RGD:1624291
RGD:1600115
G Ryk receptor-like tyrosine kinase JBrowse link 8 111,326,339 111,398,640 RGD:1624291
RGD:1600115
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
RGD:13792537
G Sema3b semaphorin 3B JBrowse link 8 116,353,791 116,362,655 RGD:13792537
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:13792537
G Sema3d semaphorin 3D JBrowse link 4 19,224,378 19,413,519 RGD:13792537
G Sema3e semaphorin 3E JBrowse link 4 17,314,745 17,594,659 RGD:13792537
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291
RGD:13792537
G Sema3g semaphorin 3G JBrowse link 16 7,303,582 7,315,214 RGD:13792537
G Sema4a semaphorin 4A JBrowse link 2 187,799,568 187,823,014 RGD:13792537
G Sema4c semaphorin 4C JBrowse link 9 43,129,413 43,140,442 RGD:13792537
G Sema4d semaphorin 4D JBrowse link 17 13,516,276 13,538,513 RGD:13792537
G Sema4f ssemaphorin 4F JBrowse link 4 113,738,225 113,764,532 RGD:13792537
G Sema4g semaphorin 4G JBrowse link 1 264,738,935 264,753,399 RGD:13792537
G Sema5a semaphorin 5A JBrowse link 2 85,377,318 85,808,970 RGD:8553809
G Sema6a semaphorin 6A JBrowse link 18 41,330,519 41,451,813 RGD:13792537
G Sema6b semaphorin 6B JBrowse link 9 10,934,273 10,951,252 RGD:13792537
G Sema6c semaphorin 6C JBrowse link 2 196,330,777 196,347,218 RGD:13792537
G Sema6d semaphorin 6D JBrowse link 3 116,899,906 116,958,059 RGD:13792537
G Sema7a semaphorin 7A (John Milton Hagen blood group) JBrowse link 8 62,723,788 62,746,530 RGD:13792537
G Slit1 slit guidance ligand 1 JBrowse link 1 260,843,481 260,992,366 RGD:1358459
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:1624291
RGD:1600115
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
negative regulation of dendritic cell chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
negative regulation of endothelial cell chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hrg histidine-rich glycoprotein JBrowse link 11 81,621,274 81,639,938 RGD:1600115
RGD:1624291
G LOC681544 similar to histidine-rich glycoprotein RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
negative regulation of endothelial cell chemotaxis to fibroblast growth factor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxcl13 C-X-C motif chemokine ligand 13 JBrowse link 14 15,253,146 15,258,221 RGD:1624291
negative regulation of leukocyte chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr18 G protein-coupled receptor 18 JBrowse link 15 108,323,157 108,326,907 RGD:1624291
RGD:1600115
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:2303400
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
negative regulation of lymphocyte chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Padi2 peptidyl arginine deiminase 2 JBrowse link 5 159,428,479 159,471,113 RGD:1600115
RGD:1624291
negative regulation of macrophage chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:1624291
RGD:1600115
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:1624291
RGD:1600115
G Ddt D-dopachrome tautomerase JBrowse link 20 13,827,153 13,829,624 RGD:1624291
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Mmp28 matrix metallopeptidase 28 JBrowse link 10 70,660,691 70,681,672 RGD:1624291
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
RGD:1600115
negative regulation of monocyte chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:1624291
RGD:1600115
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:1600115
RGD:1624291
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:2303400
G Nbl1 NBL1, DAN family BMP antagonist JBrowse link 5 157,524,569 157,535,701 RGD:1624291
RGD:1600115
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:2303400
negative regulation of natural killer cell chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:1624291
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:1624291
RGD:1600115
negative regulation of negative chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1600115
RGD:1624291
G Robo2 roundabout guidance receptor 2 JBrowse link 11 11,062,866 12,618,793 RGD:1624291
RGD:1600115
negative regulation of neutrophil chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C5ar2 complement component 5a receptor 2 JBrowse link 1 78,165,155 78,183,426 RGD:1624291
RGD:1600115
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1600115
RGD:1624291
negative regulation of positive chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angpt2 angiopoietin 2 JBrowse link 16 75,966,480 76,016,147 RGD:1624291
RGD:1600115
negative regulation of retinal ganglion cell axon guidance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1600115
RGD:1624291
negative regulation of smooth muscle cell chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:1624291
RGD:1600115
G Coro1b coronin 1B JBrowse link 1 219,397,827 219,403,253 RGD:10047170
RGD:1600115
RGD:1624291
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:10401938
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    locomotion 1834
      negative regulation of locomotion 350
        negative regulation of chemotaxis 57
          negative regulation of Schwann cell chemotaxis 0
          negative regulation of astrocyte chemotaxis 0
          negative regulation of axon guidance + 27
          negative regulation of cell chemotaxis to fibroblast growth factor + 1
          negative regulation of chemokine activity 0
          negative regulation of chemotaxis to arachidonic acid 0
          negative regulation of endothelial cell chemotaxis + 5
          negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
          negative regulation of fibroblast chemotaxis 0
          negative regulation of leukocyte chemotaxis + 17
          negative regulation of muscle cell chemotaxis toward tendon cell 0
          negative regulation of negative chemotaxis + 2
          negative regulation of positive chemotaxis + 1
          negative regulation of smooth muscle cell chemotaxis 4
Path 2
Term Annotations click to browse term
  biological_process 18008
    biological regulation 12699
      regulation of biological process 12031
        regulation of response to stimulus 3838
          regulation of response to external stimulus 963
            regulation of chemotaxis 225
              negative regulation of chemotaxis 57
                negative regulation of Schwann cell chemotaxis 0
                negative regulation of astrocyte chemotaxis 0
                negative regulation of axon guidance + 27
                negative regulation of cell chemotaxis to fibroblast growth factor + 1
                negative regulation of chemokine activity 0
                negative regulation of chemotaxis to arachidonic acid 0
                negative regulation of endothelial cell chemotaxis + 5
                negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor 0
                negative regulation of fibroblast chemotaxis 0
                negative regulation of leukocyte chemotaxis + 17
                negative regulation of muscle cell chemotaxis toward tendon cell 0
                negative regulation of negative chemotaxis + 2
                negative regulation of positive chemotaxis + 1
                negative regulation of smooth muscle cell chemotaxis 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.