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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of membrane protein ectodomain proteolysis
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Accession:GO:0051044 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.
Synonyms:exact_synonym: up regulation of membrane protein ectodomain proteolysis;   upregulation of membrane protein ectodomain proteolysis
 narrow_synonym: activation of membrane protein ectodomain proteolysis;   stimulation of membrane protein ectodomain proteolysis


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positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 ISO
IBA
(PMID:15220135), (PMID:17548643)
PMID:21873635
(MGI:3040545|PMID:14761956)
RGD PMID:14761956, PMID:15220135, PMID:17548643, PMID:21873635 MGI:3040545, RGD:13792537 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 ISO (MGI:1326990|PMID:9857183) RGD PMID:9857183 MGI:1326990 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Adra2a adrenoceptor alpha 2A ISO (PMID:17655843) RGD PMID:17655843 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Apoe apolipoprotein E IEA
ISO
GO_REF:0000107
UniProtKB:P05067:PRO_0000000092 (PMID:15950758), (PMID:25015123)
Ensembl
RGD
PMID:15950758, PMID:25015123 GO_REF:0000107 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein ISO UniProtKB:P02649 (PMID:25015123) RGD PMID:25015123 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 IEA
ISO
ISS
GO_REF:0000107
(MGI:5447609|PMID:17720976)
GO_REF:0000024
(PMID:17720976)
Ensembl
RGD
UniProt
PMID:17720976 GO_REF:0000024, GO_REF:0000107, MGI:5447609 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Ifng interferon gamma ISO (PMID:18373975) RGD PMID:18373975 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta ISO
IEA
(PMID:18373975)
GO_REF:0000107
RGD
Ensembl
PMID:18373975 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Nrdc nardilysin convertase ISO
IEA
(PMID:18355445)
GO_REF:0000107
RGD
Ensembl
PMID:18355445 GO_REF:0000107 NCBI chr 5:128,629,949...128,694,209
Ensembl chr 5:128,629,942...128,694,060
JBrowse link
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 ISO (PMID:15280379) RGD PMID:15280379 NCBI chr 3:80,072,425...80,081,058
Ensembl chr 3:80,072,489...80,081,047
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a ISO (MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:5702499 NCBI chr 1:134,699,053...134,742,512
Ensembl chr 1:134,699,299...134,742,514
JBrowse link
G Sh3d19 SH3 domain containing 19 ISO (PMID:15280379) RGD PMID:15280379 NCBI chr 2:185,268,028...185,431,834
Ensembl chr 2:185,268,259...185,431,354
JBrowse link
G Snx33 sorting nexin 33 ISO (PMID:18353773), (PMID:18419754) RGD PMID:18353773, PMID:18419754 NCBI chr 8:61,584,656...61,596,055
Ensembl chr 8:61,584,656...61,595,032
JBrowse link
G Snx9 sorting nexin 9 ISO (PMID:18353773) RGD PMID:18353773 NCBI chr 1:46,780,142...46,826,250
Ensembl chr 1:46,779,860...46,825,830
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:18373975) RGD PMID:18373975 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO
IBA
(PMID:22480688)
PMID:21873635
RGD PMID:22480688, PMID:21873635 RGD:13792537 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      catabolic process 2562
        positive regulation of catabolic process 483
          positive regulation of cellular catabolic process 415
            positive regulation of membrane protein ectodomain proteolysis 16
Path 2
Term Annotations click to browse term
  biological_process 20030
    metabolic process 12185
      organic substance metabolic process 11552
        macromolecule metabolic process 9966
          protein metabolic process 6023
            cellular protein metabolic process 5350
              regulation of cellular protein metabolic process 2556
                positive regulation of cellular protein metabolic process 1507
                  positive regulation of proteolysis 376
                    positive regulation of membrane protein ectodomain proteolysis 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.