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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of membrane protein ectodomain proteolysis
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Accession:GO:0051045 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.
Synonyms:exact_synonym: down regulation of membrane protein ectodomain proteolysis;   downregulation of membrane protein ectodomain proteolysis
 narrow_synonym: inhibition of membrane protein ectodomain proteolysis


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negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 ISO
ISS
(PMID:18383040)
GO_REF:0000024
RGD
UniProt
PMID:18383040 GO_REF:0000024 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 ISO (MGI:MGI:5702499|PMID:26651291) RGD PMID:26651291 MGI:MGI:5702499 NCBI chr 2:206,928,708...206,997,915
Ensembl chr 2:206,931,204...206,997,519
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 ISO (PMID:12207026) RGD PMID:12207026 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO
IBA
(PMID:12714508)
PMID:21873635
RGD PMID:12714508, PMID:21873635 RGD:13792537 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO
IBA
IEA
(PMID:18383040)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:18383040, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:147,156,948...147,163,467
Ensembl chr 4:147,156,948...147,163,467
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      catabolic process 2560
        negative regulation of catabolic process 320
          negative regulation of cellular catabolic process 253
            negative regulation of membrane protein ectodomain proteolysis 7
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          protein metabolic process 6264
            cellular protein metabolic process 5570
              regulation of cellular protein metabolic process 2805
                negative regulation of cellular protein metabolic process 1135
                  negative regulation of proteolysis 403
                    negative regulation of membrane protein ectodomain proteolysis 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.