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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of secretion
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Accession:GO:0051048 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
Synonyms:exact_synonym: down regulation of secretion;   downregulation of secretion
 narrow_synonym: inhibition of secretion


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negative regulation of secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EGF epidermal growth factor JBrowse link 4 109,912,883 110,013,766 RGD:2290271
G ERBB3 erb-b2 receptor tyrosine kinase 3 JBrowse link 12 56,080,025 56,103,507 RGD:2290271
G NPY2R neuropeptide Y receptor Y2 JBrowse link 4 155,173,514 155,217,076 RGD:2290271
G NRG1 neuregulin 1 JBrowse link 8 31,639,245 32,774,046 RGD:2290271
negative regulation of adiponectin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:2290271
G RAB11FIP1 RAB11 family interacting protein 1 JBrowse link 8 37,858,618 37,899,497 RGD:2290271
G RAB11FIP3 RAB11 family interacting protein 3 JBrowse link 16 425,621 523,011 RGD:2290271
G RAB11FIP5 RAB11 family interacting protein 5 JBrowse link 2 73,073,382 73,112,948 RGD:2290271
negative regulation of arachidonic acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP5PF ATP synthase peripheral stalk subunit F6 JBrowse link 21 25,724,480 25,735,654 RGD:2290271
G PLA2R1 phospholipase A2 receptor 1 JBrowse link 2 159,932,002 160,062,615 RGD:2290271
negative regulation of calcium ion-dependent exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRA2A adrenoceptor alpha 2A JBrowse link 10 111,077,029 111,080,907 RGD:2290271
G CBARP CACN subunit beta associated regulatory protein JBrowse link 19 1,228,287 1,238,512 RGD:2290271
G GNAI2 G protein subunit alpha i2 JBrowse link 3 50,227,068 50,259,362 RGD:2290271
G NOTCH1 notch receptor 1 JBrowse link 9 136,494,433 136,546,048 RGD:2290271
G RAP1B RAP1B, member of RAS oncogene family JBrowse link 12 68,610,899 68,671,901 RGD:2290271
G REST RE1 silencing transcription factor JBrowse link 4 56,907,900 56,935,847 RGD:2290271
G STXBP3 syntaxin binding protein 3 JBrowse link 1 108,746,674 108,809,523 RGD:2290271
G SYT4 synaptotagmin 4 JBrowse link 18 43,267,892 43,277,490 RGD:2290271
G TRIM9 tripartite motif containing 9 JBrowse link 14 50,975,261 51,105,173 RGD:2290271
negative regulation of catecholamine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHGA chromogranin A JBrowse link 14 92,922,594 92,935,293 RGD:2290271
G SYT4 synaptotagmin 4 JBrowse link 18 43,267,892 43,277,490 RGD:2290271
negative regulation of chemokine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 76,819,030 76,835,315 RGD:2290271
negative regulation of constitutive secretory pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAB33B RAB33B, member RAS oncogene family JBrowse link 4 139,453,232 139,476,609 RGD:2290271
negative regulation of corticotropin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CRHBP corticotropin releasing hormone binding protein JBrowse link 5 76,952,855 76,981,143 RGD:2290271
negative regulation of cortisol secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 112,418,898 112,509,918 RGD:2290271
negative regulation of cytokine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 6 26,382,893 26,394,874 RGD:2290271
G CIDEA cell death inducing DFFA like effector a JBrowse link 18 12,254,361 12,277,595 RGD:2290271
G FCGR2B Fc fragment of IgG receptor IIb JBrowse link 1 161,647,243 161,678,654 RGD:2290271
G FFAR4 free fatty acid receptor 4 JBrowse link 10 93,566,178 93,590,072 RGD:2290271
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:2290271
G HDAC9 histone deacetylase 9 JBrowse link 7 18,086,825 19,002,416 RGD:2290271
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 JBrowse link 11 27,365,961 27,472,790 RGD:2290271
G LRRC32 leucine rich repeat containing 32 JBrowse link 11 76,657,524 76,670,747 RGD:2290271
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 19 53,793,584 53,824,403 RGD:2290271
G PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 JBrowse link 6 30,066,864 30,070,333 RGD:2290271
G PTGER4 prostaglandin E receptor 4 JBrowse link 5 40,679,915 40,740,936 RGD:2290271
G RGCC regulator of cell cycle JBrowse link 13 41,457,411 41,470,876 RGD:2290271
G SRGN serglycin JBrowse link 10 69,057,533 69,104,811 RGD:2290271
G SYT11 synaptotagmin 11 JBrowse link 1 155,859,502 155,885,199 RGD:2290271
G TNFRSF4 TNF receptor superfamily member 4 JBrowse link 1 1,211,326 1,216,812 RGD:2290271
negative regulation of cytokine secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANGPT1 angiopoietin 1 JBrowse link 8 107,249,482 107,497,918 RGD:2290271
G APOA1 apolipoprotein A1 JBrowse link 11 116,835,751 116,837,950 RGD:2290271
G APOA2 apolipoprotein A2 JBrowse link 1 161,222,292 161,223,628 RGD:2290271
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:2290271
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:2290271
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 19 42,507,306 42,528,482 RGD:2290271
G FCGR2B Fc fragment of IgG receptor IIb JBrowse link 1 161,647,243 161,678,654 RGD:2290271
negative regulation of dense core granule exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SYT4 synaptotagmin 4 JBrowse link 18 43,267,892 43,277,490 RGD:2290271
negative regulation of dopamine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABAT 4-aminobutyrate aminotransferase JBrowse link 16 8,674,617 8,784,575 RGD:2290271
G CNR1 cannabinoid receptor 1 JBrowse link 6 88,139,864 88,167,349 RGD:2290271
G DRD2 dopamine receptor D2 JBrowse link 11 113,409,595 113,475,398 RGD:2290271
G SYT11 synaptotagmin 11 JBrowse link 1 155,859,502 155,885,199 RGD:2290271
negative regulation of eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCR2 C-C motif chemokine receptor 2 JBrowse link 3 46,353,744 46,360,940 RGD:2290271
negative regulation of epinephrine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRA2A adrenoceptor alpha 2A JBrowse link 10 111,077,029 111,080,907 RGD:2290271
G ADRA2B adrenoceptor alpha 2B JBrowse link 2 96,112,876 96,116,571 RGD:2290271
G ADRA2C adrenoceptor alpha 2C JBrowse link 4 3,766,385 3,768,526 RGD:2290271
G CRH corticotropin releasing hormone JBrowse link 8 66,176,376 66,178,464 RGD:2290271
negative regulation of exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 73,151,865 73,170,393 RGD:2290271
G IL1RAPL1 interleukin 1 receptor accessory protein like 1 JBrowse link X 28,587,446 29,956,718 RGD:2290271
G RSC1A1 regulator of solute carriers 1 JBrowse link 1 15,659,713 15,662,030 RGD:2290271
G SNCA synuclein alpha JBrowse link 4 89,724,099 89,838,324 RGD:2290271
G STXBP6 syntaxin binding protein 6 JBrowse link 14 24,809,654 25,050,297 RGD:2290271
negative regulation of exosomal secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 161,347,417 162,727,802 RGD:2290271
G RAB7A RAB7A, member RAS oncogene family JBrowse link 3 128,726,183 128,814,798 RGD:2290271
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 18 63,389,190 63,422,495 RGD:2290271
negative regulation of extracellular matrix constituent secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADTRP androgen dependent TFPI regulating protein JBrowse link 6 11,713,523 11,779,628 RGD:2290271
G NOTCH1 notch receptor 1 JBrowse link 9 136,494,433 136,546,048 RGD:2290271
G TNFRSF1A TNF receptor superfamily member 1A JBrowse link 12 6,328,771 6,342,076 RGD:2290271
G TNFRSF1B TNF receptor superfamily member 1B JBrowse link 1 12,166,948 12,209,222 RGD:2290271
negative regulation of follicle-stimulating hormone secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G INHA inhibin subunit alpha JBrowse link 2 219,572,310 219,575,711 RGD:2290271
G INHBA inhibin subunit beta A JBrowse link 7 41,685,101 41,710,532 RGD:2290271
G INHBB inhibin subunit beta B JBrowse link 2 120,346,136 120,351,803 RGD:2290271
negative regulation of gamma-aminobutyric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABAT 4-aminobutyrate aminotransferase JBrowse link 16 8,674,617 8,784,575 RGD:2290271
G HTR1B 5-hydroxytryptamine receptor 1B JBrowse link 6 77,460,924 77,463,491 RGD:2290271
negative regulation of gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NMU neuromedin U JBrowse link 4 55,595,231 55,636,793 RGD:2290271
G OXT oxytocin/neurophysin I prepropeptide JBrowse link 20 3,068,871 3,072,517 RGD:2290271
G OXTR oxytocin receptor JBrowse link 3 8,750,403 8,769,614 RGD:2290271
G PTGER3 prostaglandin E receptor 3 JBrowse link 1 70,852,358 71,047,816 RGD:2290271
G TFF2 trefoil factor 2 JBrowse link 21 42,346,357 42,350,994 RGD:2290271
G UCN urocortin JBrowse link 2 27,307,400 27,308,445 RGD:2290271
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SCT secretin JBrowse link 11 626,095 627,692 RGD:2290271
negative regulation of glucagon secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CARTPT CART prepropeptide JBrowse link 5 71,719,275 71,721,045 RGD:2290271
G CRH corticotropin releasing hormone JBrowse link 8 66,176,376 66,178,464 RGD:2290271
G FAM3D FAM3 metabolism regulating signaling molecule D JBrowse link 3 58,633,943 58,666,843 RGD:2290271
G LEP leptin JBrowse link 7 128,241,201 128,257,629 RGD:2290271
negative regulation of glucocorticoid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CRY1 cryptochrome circadian regulator 1 JBrowse link 12 106,991,364 107,093,872 RGD:2290271
G CRY2 cryptochrome circadian regulator 2 JBrowse link 11 45,847,118 45,883,248 RGD:2290271
negative regulation of glutamate secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADORA1 adenosine A1 receptor JBrowse link 1 203,127,705 203,167,405 RGD:2290271
G GRM7 glutamate metabotropic receptor 7 JBrowse link 3 6,861,115 7,743,038 RGD:2290271
G HRH3 histamine receptor H3 JBrowse link 20 62,213,845 62,220,278 RGD:2290271
G NPY5R neuropeptide Y receptor Y5 JBrowse link 4 163,336,968 163,352,277 RGD:2290271
G TRH thyrotropin releasing hormone JBrowse link 3 129,974,720 129,977,935 RGD:2290271
negative regulation of gonadotropin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GJA1 gap junction protein alpha 1 JBrowse link 6 121,435,646 121,449,727 RGD:2290271
G NPVF neuropeptide VF precursor JBrowse link 7 25,224,570 25,228,486 RGD:2290271
negative regulation of growth hormone secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KALRN kalirin RhoGEF kinase JBrowse link 3 124,033,341 124,726,325 RGD:2290271
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 112,418,898 112,509,918 RGD:2290271
negative regulation of hormone secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 186,842,710 186,858,463 RGD:2290271
G ADORA1 adenosine A1 receptor JBrowse link 1 203,127,705 203,167,405 RGD:2290271
G CHGA chromogranin A JBrowse link 14 92,922,594 92,935,293 RGD:2290271
G EDN1 endothelin 1 JBrowse link 6 12,256,463 12,297,194 RGD:2290271
G FGF23 fibroblast growth factor 23 JBrowse link 12 4,368,227 4,379,712 RGD:2290271
G IL11 interleukin 11 JBrowse link 19 55,364,382 55,370,463 RGD:2290271
G LIF LIF interleukin 6 family cytokine JBrowse link 22 30,240,453 30,257,487 RGD:2290271
G NMB neuromedin B JBrowse link 15 84,655,132 84,658,611 RGD:2290271
G OSM oncostatin M JBrowse link 22 30,262,829 30,266,851 RGD:2290271
G UCN urocortin JBrowse link 2 27,307,400 27,308,445 RGD:2290271
negative regulation of icosanoid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGTR2 angiotensin II receptor type 2 JBrowse link X 116,170,744 116,174,974 RGD:2290271
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 JBrowse link 19 15,878,023 15,898,074 RGD:2290271
negative regulation of immunoglobulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD22 CD22 molecule JBrowse link 19 35,329,169 35,347,361 RGD:2290271
G IL33 interleukin 33 JBrowse link 9 6,214,591 6,257,983 RGD:2290271
G TMBIM6 transmembrane BAX inhibitor motif containing 6 JBrowse link 12 49,741,557 49,764,934 RGD:2290271
negative regulation of insulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCC8 ATP binding cassette subfamily C member 8 JBrowse link 11 17,392,498 17,476,849 RGD:2290271
G ACVR1C activin A receptor type 1C JBrowse link 2 157,526,767 157,628,864 RGD:2290271
G ADRA2A adrenoceptor alpha 2A JBrowse link 10 111,077,029 111,080,907 RGD:2290271
G BMP8A bone morphogenetic protein 8a JBrowse link 1 39,491,626 39,529,869 RGD:2290271
G CCN3 cellular communication network factor 3 JBrowse link 8 119,416,446 119,424,434 RGD:2290271
G CHGA chromogranin A JBrowse link 14 92,922,594 92,935,293 RGD:2290271
G DRD2 dopamine receptor D2 JBrowse link 11 113,409,595 113,475,398 RGD:2290271
G ENHO energy homeostasis associated JBrowse link 9 34,521,043 34,522,990 RGD:2290271
G FAM3D FAM3 metabolism regulating signaling molecule D JBrowse link 3 58,633,943 58,666,843 RGD:2290271
G GHRL ghrelin and obestatin prepropeptide JBrowse link 3 10,285,666 10,292,947 RGD:2290271
G GHSR growth hormone secretagogue receptor JBrowse link 3 172,443,291 172,448,456 RGD:2290271
G HADH hydroxyacyl-CoA dehydrogenase JBrowse link 4 107,989,714 108,035,175 RGD:2290271
G INHBB inhibin subunit beta B JBrowse link 2 120,346,136 120,351,803 RGD:2290271
G IRS1 insulin receptor substrate 1 JBrowse link 2 226,731,317 226,798,790 RGD:2290271
G KCNB1 potassium voltage-gated channel subfamily B member 1 JBrowse link 20 49,363,877 49,484,033 RGD:2290271
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 JBrowse link 11 17,385,246 17,389,346 RGD:2290271
G MIDN midnolin JBrowse link 19 1,248,552 1,259,143 RGD:2290271
G MTNR1B melatonin receptor 1B JBrowse link 11 92,969,623 92,986,241 RGD:2290271
G NPFF neuropeptide FF-amide peptide precursor JBrowse link 12 53,506,688 53,507,484 RGD:2290271
G PFKL phosphofructokinase, liver type JBrowse link 21 44,300,040 44,327,373 RGD:2290271
G PPP3CA protein phosphatase 3 catalytic subunit alpha JBrowse link 4 101,023,418 101,348,295 RGD:2290271
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 161,347,417 162,727,802 RGD:2290271
G PSMD9 proteasome 26S subunit, non-ATPase 9 JBrowse link 12 121,888,790 121,918,297 RGD:2290271
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 112,418,898 112,509,918 RGD:2290271
G REST RE1 silencing transcription factor JBrowse link 4 56,907,900 56,935,847 RGD:2290271
G SFRP1 secreted frizzled related protein 1 JBrowse link 8 41,261,962 41,309,473 RGD:2290271
G SIRT4 sirtuin 4 JBrowse link 12 120,290,639 120,313,242 RGD:2290271
G SREBF1 sterol regulatory element binding transcription factor 1 JBrowse link 17 17,811,334 17,837,017 RGD:2290271
G STXBP5L syntaxin binding protein 5 like JBrowse link 3 120,908,205 121,424,761 RGD:2290271
G SYTL4 synaptotagmin like 4 JBrowse link X 100,671,964 100,732,137 RGD:2290271
G VSNL1 visinin like 1 JBrowse link 2 17,539,972 17,657,018 RGD:2290271
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRA2A adrenoceptor alpha 2A JBrowse link 10 111,077,029 111,080,907 RGD:2290271
G ENY2 ENY2 transcription and export complex 2 subunit JBrowse link 8 109,334,347 109,345,954 RGD:2290271
G FKBP1B FKBP prolyl isomerase 1B JBrowse link 2 24,033,205 24,067,743 RGD:2290271
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 75,336,334 75,362,116 RGD:2290271
G JAGN1 jagunal homolog 1 JBrowse link 3 9,890,610 9,894,349 RGD:2290271
G KLF7 Kruppel like factor 7 JBrowse link 2 207,074,137 207,173,851 RGD:2290271
G NDUFAF2 NADH:ubiquinone oxidoreductase complex assembly factor 2 JBrowse link 5 60,945,205 61,153,026 RGD:2290271
G PIM3 Pim-3 proto-oncogene, serine/threonine kinase JBrowse link 22 49,960,772 49,964,072 RGD:2290271
negative regulation of interferon-beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
negative regulation of interferon-gamma secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL36RN interleukin 36 receptor antagonist JBrowse link 2 113,058,638 113,064,744 RGD:2290271
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
negative regulation of interleukin-1 alpha secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL1R2 interleukin 1 receptor type 2 JBrowse link 2 101,991,805 102,028,544 RGD:2290271
negative regulation of interleukin-1 beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOA1 apolipoprotein A1 JBrowse link 11 116,835,751 116,837,950 RGD:2290271
G CARD16 caspase recruitment domain family member 16 JBrowse link 11 105,040,218 105,045,416 RGD:2290271
G CARD17 caspase recruitment domain family member 17 JBrowse link 11 105,080,453 105,101,492 RGD:2290271
G CARD18 caspase recruitment domain family member 18 JBrowse link 11 105,137,714 105,139,769 RGD:2290271
G CARD8 caspase recruitment domain family member 8 JBrowse link 19 48,203,148 48,256,264 RGD:2290271
G CPTP ceramide-1-phosphate transfer protein JBrowse link 1 1,324,757 1,328,896 RGD:2290271
G NLRC4 NLR family CARD domain containing 4 JBrowse link 2 32,224,449 32,265,743 RGD:2290271
G NLRP2B NLR family pyrin domain containing 2B JBrowse link X 57,677,067 57,680,260 RGD:2290271
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 247,416,156 247,449,108 RGD:2290271
G NLRP7 NLR family pyrin domain containing 7 JBrowse link 19 54,923,509 54,965,184 RGD:2290271
G PML promyelocytic leukemia JBrowse link 15 73,994,673 74,047,827 RGD:2290271
G PYDC1 pyrin domain containing 1 JBrowse link 16 31,215,962 31,217,093 RGD:2290271
G PYDC2 pyrin domain containing 2 JBrowse link 3 191,461,163 191,461,456 RGD:2290271
G SERPINB1 serpin family B member 1 JBrowse link 6 2,832,332 2,842,012 RGD:2290271
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 6 137,866,317 137,883,312 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
negative regulation of interleukin-1 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GAS6 growth arrest specific 6 JBrowse link 13 113,820,549 113,864,076 RGD:2290271
G NLRP12 NLR family pyrin domain containing 12 JBrowse link 19 53,793,584 53,824,403 RGD:2290271
negative regulation of interleukin-10 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 47,231,532 47,309,910 RGD:2290271
negative regulation of interleukin-12 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LILRA5 leukocyte immunoglobulin like receptor A5 JBrowse link 19 54,307,070 54,313,166 RGD:2290271
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
G TLR8 toll like receptor 8 JBrowse link X 12,906,620 12,923,169 RGD:2290271
negative regulation of interleukin-13 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG2 arginase 2 JBrowse link 14 67,619,920 67,651,708 RGD:2290271
G IFNA2 interferon alpha 2 JBrowse link 9 21,384,255 21,385,398 RGD:2290271
G LILRA5 leukocyte immunoglobulin like receptor A5 JBrowse link 19 54,307,070 54,313,166 RGD:2290271
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 47,231,532 47,309,910 RGD:2290271
negative regulation of interleukin-17 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG2 arginase 2 JBrowse link 14 67,619,920 67,651,708 RGD:2290271
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,031,762 14,053,218 RGD:2290271
negative regulation of interleukin-2 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD34 CD34 molecule JBrowse link 1 207,880,972 207,911,125 RGD:2290271
G EZR ezrin JBrowse link 6 158,765,744 158,819,368 RGD:2290271
G GBP1 guanylate binding protein 1 JBrowse link 1 89,052,319 89,065,208 RGD:2290271
G TRIM27 tripartite motif containing 27 JBrowse link 6 28,903,002 28,923,985 RGD:2290271
negative regulation of interleukin-5 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNA2 interferon alpha 2 JBrowse link 9 21,384,255 21,385,398 RGD:2290271
G TNFRSF21 TNF receptor superfamily member 21 JBrowse link 6 47,231,532 47,309,910 RGD:2290271
negative regulation of interleukin-6 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BANK1 B cell scaffold protein with ankyrin repeats 1 JBrowse link 4 101,790,482 102,074,812 RGD:2290271
G C1QTNF3 C1q and TNF related 3 JBrowse link 5 34,017,858 34,244,724 RGD:2290271
G C5AR2 complement component 5a receptor 2 JBrowse link 19 47,331,614 47,347,329 RGD:2290271
G CD200 CD200 molecule JBrowse link 3 112,332,573 112,362,812 RGD:2290271
G CD200R1 CD200 receptor 1 JBrowse link 3 112,921,205 112,975,103 RGD:2290271
G GAS6 growth arrest specific 6 JBrowse link 13 113,820,549 113,864,076 RGD:2290271
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,031,762 14,053,218 RGD:2290271
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 113,813,811 113,871,761 RGD:2290271
G SYT11 synaptotagmin 11 JBrowse link 1 155,859,502 155,885,199 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
negative regulation of interleukin-8 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 73,151,865 73,170,393 RGD:2290271
G ANXA4 annexin A4 JBrowse link 2 69,643,808 69,827,112 RGD:2290271
G MAPKBP1 mitogen-activated protein kinase binding protein 1 JBrowse link 15 41,774,484 41,827,855 RGD:2290271
G PTPN22 protein tyrosine phosphatase non-receptor type 22 JBrowse link 1 113,813,811 113,871,761 RGD:2290271
G SSC5D scavenger receptor cysteine rich family member with 5 domains JBrowse link 19 55,488,436 55,519,099 RGD:2290271
G TLR6 toll like receptor 6 JBrowse link 4 38,823,680 38,857,767 RGD:2290271
G TMSB4X thymosin beta 4 X-linked JBrowse link X 12,975,110 12,977,223 RGD:2290271
negative regulation of lactation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSN2 casein beta JBrowse link 4 69,955,256 69,965,762 RGD:2290271
negative regulation of luteinizing hormone secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CRH corticotropin releasing hormone JBrowse link 8 66,176,376 66,178,464 RGD:2290271
G OPRK1 opioid receptor kappa 1 JBrowse link 8 53,225,716 53,251,697 RGD:2290271
G TACR2 tachykinin receptor 2 JBrowse link 10 69,403,903 69,416,918 RGD:2290271
negative regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD300A CD300a molecule JBrowse link 17 74,466,373 74,484,798 RGD:2290271
G CD84 CD84 molecule JBrowse link 1 160,541,094 160,579,516 RGD:2290271
G FOXF1 forkhead box F1 JBrowse link 16 86,510,527 86,515,422 RGD:2290271
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:2290271
G IL13RA2 interleukin 13 receptor subunit alpha 2 JBrowse link X 115,003,982 115,017,616 RGD:2290271
G LGALS9 galectin 9 JBrowse link 17 27,631,172 27,649,560 RGD:2290271
negative regulation of matrix metallopeptidase secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD200 CD200 molecule JBrowse link 3 112,332,573 112,362,812 RGD:2290271
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 15 90,083,045 90,102,554 RGD:2290271
negative regulation of mucus secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADA adenosine deaminase JBrowse link 20 44,619,519 44,651,758 RGD:2290271
G ADORA1 adenosine A1 receptor JBrowse link 1 203,127,705 203,167,405 RGD:2290271
negative regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HLA-F major histocompatibility complex, class I, F JBrowse link 6 29,723,340 29,740,355 RGD:2290271
negative regulation of neurotransmitter secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASIC1 acid sensing ion channel subunit 1 JBrowse link 12 50,057,596 50,083,622 RGD:2290271
G NF1 neurofibromin 1 JBrowse link 17 31,094,927 31,377,677 RGD:2290271
G PNKD PNKD metallo-beta-lactamase domain containing JBrowse link 2 218,270,485 218,346,793 RGD:2290271
G SLC30A1 solute carrier family 30 member 1 JBrowse link 1 211,571,568 211,579,161 RGD:2290271
G SYT11 synaptotagmin 11 JBrowse link 1 155,859,502 155,885,199 RGD:2290271
negative regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABR ABR activator of RhoGEF and GTPase JBrowse link 17 1,003,519 1,229,722 RGD:2290271
G BCR BCR activator of RhoGEF and GTPase JBrowse link 22 23,180,509 23,318,037 RGD:2290271
negative regulation of norepinephrine secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRA2A adrenoceptor alpha 2A JBrowse link 10 111,077,029 111,080,907 RGD:2290271
G ADRA2B adrenoceptor alpha 2B JBrowse link 2 96,112,876 96,116,571 RGD:2290271
G ADRA2C adrenoceptor alpha 2C JBrowse link 4 3,766,385 3,768,526 RGD:2290271
G AGTR2 angiotensin II receptor type 2 JBrowse link X 116,170,744 116,174,974 RGD:2290271
G CRH corticotropin releasing hormone JBrowse link 8 66,176,376 66,178,464 RGD:2290271
G GHSR growth hormone secretagogue receptor JBrowse link 3 172,443,291 172,448,456 RGD:2290271
G P2RY1 purinergic receptor P2Y1 JBrowse link 3 152,835,131 152,841,439 RGD:2290271
G P2RY12 purinergic receptor P2Y12 JBrowse link 3 151,336,843 151,384,812 RGD:2290271
negative regulation of pancreatic juice secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,248,300 47,269,033 RGD:2290271
G STK39 serine/threonine kinase 39 JBrowse link 2 167,954,020 168,247,595 RGD:2290271
G WNK3 WNK lysine deficient protein kinase 3 JBrowse link X 54,192,823 54,358,695 RGD:2290271
G WNK4 WNK lysine deficient protein kinase 4 JBrowse link 17 42,779,701 42,797,066 RGD:2290271
negative regulation of peptide secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD74 CD74 molecule JBrowse link 5 150,400,041 150,412,936 RGD:2290271
negative regulation of prolactin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA5 annexin A5 JBrowse link 4 121,667,946 121,696,994 RGD:2290271
negative regulation of prostaglandin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACSL4 acyl-CoA synthetase long chain family member 4 JBrowse link X 109,641,335 109,733,392 RGD:2290271
G ATP5PF ATP synthase peripheral stalk subunit F6 JBrowse link 21 25,724,480 25,735,654 RGD:2290271
negative regulation of protein secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADTRP androgen dependent TFPI regulating protein JBrowse link 6 11,713,523 11,779,628 RGD:2290271
G APOE apolipoprotein E JBrowse link 19 44,905,796 44,909,395 RGD:2290271
G CYP51A1 cytochrome P450 family 51 subfamily A member 1 JBrowse link 7 92,112,149 92,134,745 RGD:2290271
G DPH3 diphthamide biosynthesis 3 JBrowse link 3 16,257,061 16,264,943 RGD:2290271
G DRD2 dopamine receptor D2 JBrowse link 11 113,409,595 113,475,398 RGD:2290271
G DRD3 dopamine receptor D3 JBrowse link 3 114,127,580 114,199,407 RGD:2290271
G DRD4 dopamine receptor D4 JBrowse link 11 637,269 640,706 RGD:2290271
G ERP29 endoplasmic reticulum protein 29 JBrowse link 12 112,013,340 112,023,449 RGD:2290271
G FRMD4A FERM domain containing 4A JBrowse link 10 13,638,300 14,330,924 RGD:2290271
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 75,336,334 75,362,116 RGD:2290271
G INS insulin JBrowse link 11 2,159,779 2,161,209 RGD:2290271
G RHBDF1 rhomboid 5 homolog 1 JBrowse link 16 58,059 76,355 RGD:2290271
G RHBDF2 rhomboid 5 homolog 2 JBrowse link 17 76,470,893 76,501,440 RGD:2290271
G RSAD2 radical S-adenosyl methionine domain containing 2 JBrowse link 2 6,865,733 6,898,239 RGD:2290271
G SERGEF secretion regulating guanine nucleotide exchange factor JBrowse link 11 17,788,048 18,013,047 RGD:2290271
G SRCIN1 SRC kinase signaling inhibitor 1 JBrowse link 17 38,530,015 38,607,166 RGD:2290271
G SYT4 synaptotagmin 4 JBrowse link 18 43,267,892 43,277,490 RGD:2290271
negative regulation of renal sodium excretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADORA1 adenosine A1 receptor JBrowse link 1 203,127,705 203,167,405 RGD:2290271
G AVPR2 arginine vasopressin receptor 2 JBrowse link X 153,902,625 153,907,166 RGD:2290271
G COMT catechol-O-methyltransferase JBrowse link 22 19,941,772 19,969,975 RGD:2290271
G SPX spexin hormone JBrowse link 12 21,526,296 21,532,947 RGD:2290271
negative regulation of renin secretion into blood stream term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2R coagulation factor II thrombin receptor JBrowse link 5 76,716,126 76,735,770 RGD:2290271
negative regulation of saliva secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DCANP1 dendritic cell associated nuclear protein JBrowse link 5 135,444,214 135,447,348 RGD:2290271
G NEUROG1 neurogenin 1 JBrowse link 5 135,534,282 135,535,964 RGD:2290271
G TIFAB TIFA inhibitor JBrowse link 5 135,444,226 135,452,351 RGD:2290271
negative regulation of secretion by cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VAMP3 vesicle associated membrane protein 3 JBrowse link 1 7,771,275 7,781,432 RGD:2290271
G VAMP8 vesicle associated membrane protein 8 JBrowse link 2 85,577,535 85,582,031 RGD:2290271
negative regulation of secretion of lysosomal enzymes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,248,300 47,269,033 RGD:2290271
negative regulation of serotonin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CNR1 cannabinoid receptor 1 JBrowse link 6 88,139,864 88,167,349 RGD:2290271
G HRH3 histamine receptor H3 JBrowse link 20 62,213,845 62,220,278 RGD:2290271
G HTR1B 5-hydroxytryptamine receptor 1B JBrowse link 6 77,460,924 77,463,491 RGD:2290271
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
G MAOB monoamine oxidase B JBrowse link X 43,766,610 43,882,450 RGD:2290271
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PPP1R9A protein phosphatase 1 regulatory subunit 9A JBrowse link 7 94,907,202 95,296,415 RGD:2290271
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 161,347,417 162,727,802 RGD:2290271
negative regulation of synaptic vesicle exocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 7 140,719,331 140,924,929 RGD:2290271
G FMR1 FMRP translational regulator 1 JBrowse link X 147,911,919 147,951,127 RGD:2290271
G RAP1A RAP1A, member of RAS oncogene family JBrowse link 1 111,542,009 111,716,695 RGD:2290271
G RAP1B RAP1B, member of RAS oncogene family JBrowse link 12 68,610,899 68,671,901 RGD:2290271
G SYT4 synaptotagmin 4 JBrowse link 18 43,267,892 43,277,490 RGD:2290271
negative regulation of transforming growth factor-beta secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FBLN1 fibulin 1 JBrowse link 22 45,502,883 45,601,135 RGD:2290271
G FN1 fibronectin 1 JBrowse link 2 215,360,440 215,436,167 RGD:2290271
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
negative regulation of tumor necrosis factor secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARG2 arginase 2 JBrowse link 14 67,619,920 67,651,708 RGD:2290271
G CX3CL1 C-X3-C motif chemokine ligand 1 JBrowse link 16 57,372,490 57,385,044 RGD:2290271
G DEFB114 defensin beta 114 JBrowse link 6 49,960,249 49,964,164 RGD:2290271
G GHRL ghrelin and obestatin prepropeptide JBrowse link 3 10,285,666 10,292,947 RGD:2290271
G GHSR growth hormone secretagogue receptor JBrowse link 3 172,443,291 172,448,456 RGD:2290271
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,031,762 14,053,218 RGD:2290271
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:2290271
G SYT11 synaptotagmin 11 JBrowse link 1 155,859,502 155,885,199 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
negative regulation of Wnt protein secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G OPRM1 opioid receptor mu 1 JBrowse link 6 154,010,496 154,246,867 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17733
    negative regulation of biological process 5515
      negative regulation of transport 503
        negative regulation of secretion 229
          negative regulation of bile acid secretion 0
          negative regulation of defecation + 0
          negative regulation of gamma-aminobutyric acid secretion 2
          negative regulation of gastric acid secretion + 7
          negative regulation of icosanoid secretion + 5
          negative regulation of lactation 1
          negative regulation of mucus secretion 2
          negative regulation of pancreatic juice secretion + 4
          negative regulation of peptide secretion + 138
          negative regulation of renal sodium excretion + 4
          negative regulation of saliva secretion 3
          negative regulation of secretion by cell + 203
Path 2
Term Annotations click to browse term
  biological_process 17733
    biological regulation 12487
      regulation of biological process 11806
        regulation of localization 2819
          regulation of transport 1899
            regulation of secretion 833
              negative regulation of secretion 229
                negative regulation of bile acid secretion 0
                negative regulation of defecation + 0
                negative regulation of gamma-aminobutyric acid secretion 2
                negative regulation of gastric acid secretion + 7
                negative regulation of icosanoid secretion + 5
                negative regulation of lactation 1
                negative regulation of mucus secretion 2
                negative regulation of pancreatic juice secretion + 4
                negative regulation of peptide secretion + 138
                negative regulation of renal sodium excretion + 4
                negative regulation of saliva secretion 3
                negative regulation of secretion by cell + 203
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.