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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lipid biosynthetic process
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Accession:GO:0051055 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
Synonyms:exact_synonym: down regulation of lipid biosynthetic process;   downregulation of lipid biosynthetic process;   negative regulation of lipid anabolism;   negative regulation of lipid biosynthesis;   negative regulation of lipid formation;   negative regulation of lipid synthesis;   negative regulation of lipogenesis
 narrow_synonym: inhibition of lipid biosynthetic process


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negative regulation of lipid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
G Asxl3 ASXL transcriptional regulator 3 JBrowse link 18 13,322,148 13,496,230 RGD:1600115
RGD:1624291
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Enho energy homeostasis associated JBrowse link 5 58,018,039 58,019,836 RGD:1624291
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1600115
RGD:1624291
G LOC259246 alpha-2u globulin PGCL1 RGD:1600115
G Serpina12 serpin family A member 12 JBrowse link 6 127,696,501 127,711,238 RGD:1624291
RGD:1600115
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:1624291
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of androgen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Malrd1 MAM and LDL receptor class A domain containing 1 JBrowse link 17 82,430,836 83,156,696 RGD:1624291
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 JBrowse link 9 53,110,628 53,120,454 RGD:1624291
RGD:13792537
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 JBrowse link 7 3,242,991 3,246,085 RGD:1624291
RGD:13792537
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 JBrowse link 10 86,545,910 86,554,478 RGD:1624291
RGD:13792537
RGD:1600115
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:1600115
RGD:1624291
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
RGD:10059686
G Erlin1 ER lipid raft associated 1 JBrowse link 1 263,810,439 263,845,762 RGD:1624291
G Erlin2 ER lipid raft associated 2 JBrowse link 16 69,179,005 69,195,452 RGD:1624291
G Idi2 isopentenyl-diphosphate delta isomerase 2 JBrowse link 17 63,107,152 63,107,469 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
RGD:1600115
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acadl acyl-CoA dehydrogenase, long chain JBrowse link 9 73,833,368 73,871,857 RGD:1624291
G Acadvl acyl-CoA dehydrogenase, very long chain JBrowse link 10 56,619,321 56,624,468 RGD:1624291
RGD:1600115
G Apoc1 apolipoprotein C1 JBrowse link 1 80,606,638 80,609,921 RGD:1624291
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1600115
RGD:1624291
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1600115
RGD:13792537
RGD:1624291
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:11059593
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:13792517
G Erlin1 ER lipid raft associated 1 JBrowse link 1 263,810,439 263,845,762 RGD:1624291
G Erlin2 ER lipid raft associated 2 JBrowse link 16 69,179,005 69,195,452 RGD:1624291
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Trib3 tribbles pseudokinase 3 JBrowse link 3 147,814,056 147,819,650 RGD:1624291
G Wdtc1 WD and tetratricopeptide repeats 1 JBrowse link 5 151,487,572 151,536,829 RGD:1624291
RGD:13792537
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lpcat1 lysophosphatidylcholine acyltransferase 1 JBrowse link 1 32,379,431 32,429,917 RGD:1624291
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:1624291
RGD:1600115
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:1600115
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
RGD:14697729
RGD:1600115
G Slc27a1 solute carrier family 27 member 1 JBrowse link 16 19,997,823 20,016,193 RGD:1600115
RGD:13792537
RGD:1624291
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:1624291
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca2 ATP binding cassette subfamily A member 2 JBrowse link 3 2,648,787 2,668,770 RGD:1624291
RGD:14697729
RGD:1600115
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:1624291
negative regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:2316921
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde8b phosphodiesterase 8B JBrowse link 2 24,718,548 24,955,533 RGD:1624291
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkkl1 dickkopf like acrosomal protein 1 JBrowse link 1 101,205,426 101,210,675 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:15042869
G Sik1 salt-inducible kinase 1 JBrowse link 20 10,670,747 10,680,279 RGD:1624291
RGD:1600115
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    negative regulation of biological process 5553
      negative regulation of metabolic process 3059
        negative regulation of biosynthetic process 1627
          negative regulation of lipid biosynthetic process 54
            negative regulation of abscisic acid biosynthetic process 0
            negative regulation of carotenoid biosynthetic process 0
            negative regulation of diacylglycerol biosynthetic process 0
            negative regulation of emericellamide biosynthetic process + 0
            negative regulation of ent-pimara-8(14),15-diene biosynthetic process 0
            negative regulation of fatty acid biosynthetic process + 15
            negative regulation of gibberellin biosynthetic process 0
            negative regulation of isoprene biosynthetic process 0
            negative regulation of juvenile hormone biosynthetic process 0
            negative regulation of phospholipid biosynthetic process + 5
            negative regulation of retinoic acid biosynthetic process 1
            negative regulation of sphingolipid biosynthetic process + 6
            negative regulation of steroid biosynthetic process + 24
            negative regulation of triglyceride biosynthetic process + 2
Path 2
Term Annotations click to browse term
  biological_process 19334
    biological regulation 13336
      regulation of biological process 12651
        regulation of metabolic process 6536
          regulation of primary metabolic process 5812
            regulation of lipid metabolic process 370
              negative regulation of lipid metabolic process 98
                negative regulation of lipid biosynthetic process 54
                  negative regulation of abscisic acid biosynthetic process 0
                  negative regulation of carotenoid biosynthetic process 0
                  negative regulation of diacylglycerol biosynthetic process 0
                  negative regulation of emericellamide biosynthetic process + 0
                  negative regulation of ent-pimara-8(14),15-diene biosynthetic process 0
                  negative regulation of fatty acid biosynthetic process + 15
                  negative regulation of gibberellin biosynthetic process 0
                  negative regulation of isoprene biosynthetic process 0
                  negative regulation of juvenile hormone biosynthetic process 0
                  negative regulation of phospholipid biosynthetic process + 5
                  negative regulation of retinoic acid biosynthetic process 1
                  negative regulation of sphingolipid biosynthetic process + 6
                  negative regulation of steroid biosynthetic process + 24
                  negative regulation of triglyceride biosynthetic process + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.