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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of small GTPase mediated signal transduction
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Accession:GO:0051056 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.


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regulation of small GTPase mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amot angiomotin JBrowse link X 116,751,231 116,810,238 RGD:1624291
G Arhgap18 Rho GTPase activating protein 18 JBrowse link 1 19,227,115 19,463,139 RGD:1624291
RGD:13792537
G Arhgap19 Rho GTPase activating protein 19 JBrowse link 1 261,015,083 261,051,515 RGD:13792537
G Arhgap26 Rho GTPase activating protein 26 JBrowse link 18 31,807,052 32,557,176 RGD:1600115
G Arhgap28 Rho GTPase activating protein 28 JBrowse link 9 116,057,229 116,222,440 RGD:13792537
G Arhgap40 Rho GTPase activating protein 40 JBrowse link 3 154,996,685 155,042,199 RGD:13792537
G Cdc42bpa CDC42 binding protein kinase alpha JBrowse link 13 98,231,326 98,447,762 RGD:632451
G Chn1 chimerin 1 JBrowse link 3 60,512,360 60,668,413 RGD:1600115
G Chn2 chimerin 2 JBrowse link 4 84,423,708 84,452,989 RGD:1600115
G Garnl3 GTPase activating Rap/RanGAP domain-like 3 JBrowse link 3 12,034,131 12,176,591 RGD:1600115
G Iqsec3 IQ motif and Sec7 domain ArfGEF 3 JBrowse link 4 153,948,052 154,044,493 RGD:8554231
G Ralgapa1 Ral GTPase activating protein catalytic subunit alpha 1 JBrowse link 6 76,386,971 76,661,530 RGD:1600115
G Ralgapa2 Ral GTPase activating protein catalytic subunit alpha 2 JBrowse link 3 140,451,850 140,728,305 RGD:1600115
G Ralgapb Ral GTPase activating protein non-catalytic subunit beta JBrowse link 3 154,910,291 154,983,021 RGD:1600115
G Rap1gap Rap1 GTPase-activating protein JBrowse link 5 156,008,868 156,074,350 RGD:1600115
G Rap1gap2 RAP1 GTPase activating protein 2 JBrowse link 10 61,177,936 61,395,856 RGD:1600115
G Sipa1 signal-induced proliferation-associated 1 JBrowse link 1 221,006,305 221,018,820 RGD:1600115
G Sipa1l1 signal-induced proliferation-associated 1 like 1 JBrowse link 6 106,052,212 106,163,249 RGD:1600115
G Sipa1l2 signal-induced proliferation-associated 1 like 2 JBrowse link 19 58,236,201 58,399,842 RGD:1600115
G Sipa1l3 signal-induced proliferation-associated 1 like 3 JBrowse link 1 87,260,832 87,467,846 RGD:1600115
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1600115
G Tsc2_v1 TSC complex subunit 2, variant 1 RGD:1600115
G Tsc2_v2 TSC complex subunit 2, variant 2 RGD:1600115
negative regulation of ARF protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Git1 GIT ArfGAP 1 JBrowse link 10 62,656,000 62,664,467 RGD:11344921
negative regulation of Rac protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 18 31,112,083 31,138,142 RGD:1624291
G Arhgap24 Rho GTPase activating protein 24 JBrowse link 14 8,383,211 8,600,526 RGD:1624291
RGD:13792537
G Arhgap44 Rho GTPase activating protein 44 JBrowse link 10 51,501,547 51,669,546 RGD:1600115
RGD:13792537
RGD:1624291
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Stmn3 stathmin 3 JBrowse link 3 176,808,016 176,816,108 RGD:1624291
RGD:8554560
RGD:1600115
negative regulation of Ras protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:632628
G Dgkz diacylglycerol kinase zeta JBrowse link 3 80,844,002 80,886,487 RGD:1624291
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:1624291
G Fbp1 fructose-bisphosphatase 1 JBrowse link 17 396,175 417,480 RGD:1600115
RGD:1624291
G Lztr1 leucine-zipper-like transcription regulator 1 JBrowse link 11 87,381,638 87,397,849 RGD:1624291
G Mapkap1 MAPK associated protein 1 JBrowse link 3 13,484,952 13,701,772 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:1624291
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
G Nup62 nucleoporin 62 JBrowse link 1 100,811,140 100,827,119 RGD:1624291
G Ppp2cb protein phosphatase 2 catalytic subunit beta JBrowse link 16 62,273,276 62,294,767 RGD:729591
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:1624291
G Rasa1 RAS p21 protein activator 1 JBrowse link 2 13,617,021 13,696,531 RGD:1600115
G Rasa2 RAS p21 protein activator 2 JBrowse link 8 104,417,827 104,542,313 RGD:1600115
G Rasa3 RAS p21 protein activator 3 JBrowse link 16 81,320,090 81,434,239 RGD:1600115
G Rasa4 RAS p21 protein activator 4 JBrowse link 12 23,596,989 23,624,386 RGD:1600115
G Rasal1 RAS protein activator like 1 JBrowse link 12 41,416,218 41,449,445 RGD:1600115
G Rasal3 RAS protein activator like 3 JBrowse link 7 14,403,592 14,419,570 RGD:1624291
G Spry1 sprouty RTK signaling antagonist 1 JBrowse link 2 124,400,689 124,405,331 RGD:1624291
RGD:13792537
G Spry2 sprouty RTK signaling antagonist 2 JBrowse link 15 90,172,769 90,177,823 RGD:1624291
RGD:13792537
G Spry3 sprouty RTK signaling antagonist 3 JBrowse link 12 18,930,087 18,940,622 RGD:13792537
G Spry4 sprouty RTK signaling antagonist 4 JBrowse link 18 32,593,370 32,609,890 RGD:13792537
G Stambp Stam binding protein JBrowse link 4 115,249,343 115,277,340 RGD:1624291
G Syngap1 synaptic Ras GTPase activating protein 1 JBrowse link 20 5,535,434 5,564,657 RGD:7241548
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:1598578
G Tnk1 tyrosine kinase, non-receptor, 1 JBrowse link 10 56,458,650 56,475,183 RGD:1624291
G Trim67 tripartite motif-containing 67 JBrowse link 19 57,554,665 57,593,401 RGD:1624291
negative regulation of Rho protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase JBrowse link 13 74,154,533 74,333,244 RGD:1624291
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:8554725
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:8554725
G Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 JBrowse link 18 31,112,083 31,138,142 RGD:1624291
G Arhgap35 Rho GTPase activating protein 35 JBrowse link 1 78,456,409 78,573,374 RGD:1600115
RGD:1624291
G Arhgap42 Rho GTPase activating protein 42 JBrowse link 8 7,210,999 7,446,215 RGD:1624291
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Ccdc125 coiled-coil domain containing 125 JBrowse link 2 30,685,845 30,726,617 RGD:1624291
RGD:13792537
G Cul3 cullin 3 JBrowse link 9 86,044,485 86,129,066 RGD:1600115
RGD:1624291
G Dlc1 DLC1 Rho GTPase activating protein JBrowse link 16 58,776,489 59,247,752 RGD:1600115
RGD:1624291
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1624291
RGD:1600115
G Heg1 heart development protein with EGF-like domains 1 JBrowse link 11 70,234,248 70,322,966 RGD:1624291
G Itga3 integrin subunit alpha 3 JBrowse link 10 82,855,841 82,887,755 RGD:1624291
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:1624291
RGD:1600115
G Kank1 KN motif and ankyrin repeat domains 1 JBrowse link 1 243,201,073 243,398,531 RGD:1624291
G Kctd10 potassium channel tetramerization domain containing 10 JBrowse link 12 47,992,079 48,010,531 RGD:13792537
G Kctd13 potassium channel tetramerization domain containing 13 JBrowse link 1 198,360,627 198,378,935 RGD:1624291
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:1600115
RGD:1624291
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:1600115
RGD:1624291
G Rasip1 Ras interacting protein 1 JBrowse link 1 101,609,209 101,621,648 RGD:1624291
G Ripor1 RHO family interacting cell polarization regulator 1 JBrowse link 19 37,555,940 37,584,842 RGD:1624291
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1624291
RGD:1600115
G Scai suppressor of cancer cell invasion JBrowse link 3 23,357,586 23,474,218 RGD:1624291
G Stmn1 stathmin 1 JBrowse link 5 152,680,412 152,686,807 RGD:1624291
G Tnfaip1 TNF alpha induced protein 1 JBrowse link 10 65,791,002 65,805,693 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of small GTPase mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgap12 Rho GTPase activating protein 12 JBrowse link 17 54,280,815 54,394,716 RGD:1624291
G Arhgap25 Rho GTPase activating protein 25 JBrowse link 4 119,249,682 119,327,822 RGD:1624291
RGD:13792537
G Cd2ap CD2-associated protein JBrowse link 9 20,794,680 20,858,438 RGD:1624291
RGD:1600115
G Cgnl1 cingulin-like 1 JBrowse link 8 78,126,670 78,278,490 RGD:1624291
G Cyrib CYFIP related Rac1 interactor B JBrowse link 7 104,514,566 104,641,875 RGD:1624291
G Sh3bp1 SH3-domain binding protein 1 JBrowse link 7 120,125,747 120,138,148 RGD:1600115
RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1600115
RGD:1624291
positive regulation of ARF protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 JBrowse link 9 46,657,444 46,782,545 RGD:1624291
G Mapre2 microtubule-associated protein, RP/EB family, member 2 JBrowse link 18 14,814,149 15,780,290 RGD:1624291
positive regulation of Rac protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
G Auts2 activator of transcription and developmental regulator AUTS2 JBrowse link 12 27,155,362 28,252,752 RGD:1624291
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:6907067
G Dynlt1 dynein light chain Tctex-type 1 JBrowse link 1 47,206,892 47,213,785 RGD:8553295
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:1624291
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1600115
RGD:1624291
positive regulation of Ras protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arpp19 cAMP-regulated phosphoprotein 19 JBrowse link 8 81,949,577 81,972,054 RGD:625586
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Dgki diacylglycerol kinase, iota JBrowse link 4 64,365,115 64,831,473 RGD:1624291
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1624291
RGD:13792537
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1582125
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:8553977
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Itpkb inositol-trisphosphate 3-kinase B JBrowse link 13 98,615,287 98,710,426 RGD:1624291
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:1624291
G Lrrc59 leucine rich repeat containing 59 JBrowse link 10 82,352,390 82,367,047 RGD:13792537
G Lrrd1 leucine-rich repeats and death domain containing 1 JBrowse link 4 27,403,299 27,432,649 RGD:13792537
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:8553977
G Mmd2 monocyte to macrophage differentiation-associated 2 JBrowse link 12 14,021,724 14,078,121 RGD:1624291
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1600115
RGD:1624291
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
RGD:1600115
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:1624291
RGD:1600115
G Rasgef1a RasGEF domain family, member 1A JBrowse link 4 150,063,484 150,144,203 RGD:1624291
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:7241548
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:1624291
G Rasgrp4 RAS guanyl releasing protein 4 JBrowse link 1 88,078,350 88,094,331 RGD:1600115
RGD:1624291
G Shoc2 SHOC2 leucine-rich repeat scaffold protein JBrowse link 1 274,700,621 274,751,195 RGD:1600115
RGD:13792537
RGD:1624291
G Stk19 serine/threonine kinase 19 JBrowse link 20 4,317,440 4,517,128 RGD:1624291
positive regulation of Rho protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abra actin-binding Rho activating protein JBrowse link 7 80,792,615 80,796,683 RGD:1624291
RGD:13792537
RGD:1600115
G Adgrg1 adhesion G protein-coupled receptor G1 JBrowse link 19 10,423,534 10,460,674 RGD:1600115
RGD:1624291
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:1600115
RGD:1624291
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
G Arhgef3 Rho guanine nucleotide exchange factor 3 JBrowse link 16 2,743,714 3,026,768 RGD:13792537
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:1624291
RGD:1600115
G F11r F11 receptor JBrowse link 13 89,826,272 89,850,151 RGD:1624291
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
RGD:13792537
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:13792537
RGD:1600115
G F2rl2 coagulation factor II (thrombin) receptor-like 2 JBrowse link 2 26,240,385 26,245,533 RGD:13792537
G F2rl3 F2R like thrombin or trypsin receptor 3 JBrowse link 16 18,817,797 18,819,790 RGD:13792537
G Gpr17 G protein-coupled receptor 17 JBrowse link 18 24,733,306 24,739,194 RGD:13792537
G Gpr174 G protein-coupled receptor 174 JBrowse link X 78,358,347 78,399,944 RGD:13792537
G Gpr18 G protein-coupled receptor 18 JBrowse link 15 108,323,157 108,326,907 RGD:13792537
G Gpr35 G protein-coupled receptor 35 JBrowse link 9 100,129,428 100,141,269 RGD:13792537
G Gpr4 G protein-coupled receptor 4 JBrowse link 1 80,125,639 80,136,786 RGD:13792537
RGD:1624291
G Gpr55 G protein-coupled receptor 55 JBrowse link 9 92,961,431 93,011,157 RGD:1624291
RGD:13792537
G Gpr65 G-protein coupled receptor 65 JBrowse link 6 122,248,528 122,256,115 RGD:13792537
G LOC100359656 rCG38062-like JBrowse link X 77,786,566 77,810,066 RGD:13792537
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:1600115
RGD:1624291
G Lpar2 lysophosphatidic acid receptor 2 JBrowse link 16 21,343,313 21,348,913 RGD:1624291
G Lpar4 lysophosphatidic acid receptor 4 JBrowse link X 78,042,859 78,056,347 RGD:13792537
G Lpar6 lysophosphatidic acid receptor 6 JBrowse link 15 55,126,953 55,128,762 RGD:13792537
G Mcf2l MCF.2 cell line derived transforming sequence-like JBrowse link 16 81,839,686 81,986,007 RGD:729022
RGD:1624291
G Net1 neuroepithelial cell transforming 1 JBrowse link 17 69,991,786 70,020,977 RGD:13792537
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:5508741
G P2ry10 P2Y receptor family member 10 JBrowse link X 78,158,729 78,210,413 RGD:13792537
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:10449505
G Prag1 PEAK1 related kinase activating pseudokinase 1 JBrowse link 16 59,666,794 59,730,681 RGD:11555369
G RGD1560455 similar to RIKEN cDNA A630033H20 gene JBrowse link X 78,258,495 78,284,180 RGD:13792537
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1600115
RGD:1624291
G Rtn4r reticulon 4 receptor JBrowse link 11 86,992,665 87,017,091 RGD:1624291
RGD:1600115
G Synpo2l synaptopodin 2-like JBrowse link 15 4,064,706 4,074,151 RGD:1624291
positive regulation of small GTPase mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:2325271
G Bnip2 BCL2 interacting protein 2 JBrowse link 8 76,400,333 76,426,307 RGD:1624291
G Cdon cell adhesion associated, oncogene regulated JBrowse link 8 36,625,757 36,712,091 RGD:1624291
RGD:1600115
G Frmd7 FERM domain containing 7 JBrowse link X 138,095,707 138,149,702 RGD:1624291
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:5686649
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:5686649
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
regulation of ARF protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arfgap1 ADP-ribosylation factor GTPase activating protein 1 JBrowse link 3 176,475,847 176,490,642 RGD:13792537
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 JBrowse link 5 8,666,046 8,760,458 RGD:1600115
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 JBrowse link 3 163,570,435 163,656,612 RGD:1600115
G Arfgef3 ARFGEF family member 3 JBrowse link 1 13,837,861 13,918,277 RGD:1600115
G Cyth1 cytohesin 1 JBrowse link 10 107,197,983 107,281,285 RGD:1600115
G Cyth2 cytohesin 2 JBrowse link 1 101,796,349 101,803,407 RGD:1600115
G Cyth3 cytohesin 3 JBrowse link 12 12,877,559 12,907,771 RGD:1600115
G Cyth4 cytohesin 4 JBrowse link 7 119,820,521 119,845,003 RGD:1600115
G Fbxo8 F-box protein 8 JBrowse link 16 37,131,566 37,177,033 RGD:1600115
G Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 JBrowse link 1 265,904,616 266,033,107 RGD:1600115
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 JBrowse link 4 123,400,717 123,454,656 RGD:1600115
G Iqsec2 IQ motif and Sec7 domain ArfGEF 2 JBrowse link X 22,212,137 22,293,810 RGD:1600115
G Iqsec3 IQ motif and Sec7 domain ArfGEF 3 JBrowse link 4 153,948,052 154,044,493 RGD:1600115
G Psd pleckstrin and Sec7 domain containing JBrowse link 1 266,059,331 266,074,774 RGD:1600115
G Psd2 pleckstrin and Sec7 domain containing 2 JBrowse link 18 28,781,267 28,832,429 RGD:1600115
G Psd3 pleckstrin and Sec7 domain containing 3 JBrowse link 16 23,212,165 23,789,414 RGD:1600115
G Psd4 pleckstrin and Sec7 domain containing 4 JBrowse link 3 1,478,432 1,515,094 RGD:1600115
regulation of Cdc42 protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:1624291
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:1624291
RGD:1600115
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Rit2 Ras-like without CAAX 2 JBrowse link 18 23,700,012 24,057,917 RGD:1624291
regulation of Rab protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dennd1a DENN domain containing 1A JBrowse link 3 22,061,120 22,501,502 RGD:1624291
G Dennd4b DENN domain containing 4B JBrowse link 2 189,626,922 189,642,732 RGD:1624291
G Madd MAP-kinase activating death domain JBrowse link 3 79,960,301 80,003,023 RGD:1624291
RGD:13792537
RGD:1600115
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 JBrowse link 13 44,578,208 44,649,876 RGD:1600115
G Sgsm3 small G protein signaling modulator 3 JBrowse link 7 122,203,498 122,232,993 RGD:1600115
RGD:1624291
regulation of Rac protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arf6 ADP-ribosylation factor 6 JBrowse link 6 91,697,109 91,698,257 RGD:1624291
G Arhgap17 Rho GTPase activating protein 17 JBrowse link 1 193,239,036 193,328,425 RGD:13792537
G Arhgap44 Rho GTPase activating protein 44 JBrowse link 10 51,501,547 51,669,546 RGD:13792537
G Cadm4 cell adhesion molecule 4 JBrowse link 1 81,365,200 81,369,841 RGD:1600115
RGD:1624291
G Crk CRK proto-oncogene, adaptor protein JBrowse link 10 63,829,731 63,855,999 RGD:1298803
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:9685179
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1624291
RGD:8554560
RGD:1600115
G Sh3bp1 SH3-domain binding protein 1 JBrowse link 7 120,125,747 120,138,148 RGD:13792537
G Ssx2ip SSX family member 2 interacting protein JBrowse link 2 252,263,323 252,296,049 RGD:1624291
G Tiam1 TIAM Rac1 associated GEF 1 JBrowse link 11 29,931,083 30,061,173 RGD:12050147
regulation of Ral protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ralgps1 Ral GEF with PH domain and SH3 binding motif 1 JBrowse link 3 12,182,722 12,415,081 RGD:1624291
G Ralgps2 Ral GEF with PH domain and SH3 binding motif 2 JBrowse link 13 74,446,001 74,520,640 RGD:1600115
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 JBrowse link 20 5,458,509 5,466,853 RGD:1624291
regulation of Rap protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:1624291
G Kif14 kinesin family member 14 JBrowse link 13 53,350,073 53,421,992 RGD:1624291
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:1598578
regulation of Ras protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flcn folliculin JBrowse link 10 46,153,185 46,172,331 RGD:1624291
RGD:1600115
G Foxm1 forkhead box M1 JBrowse link 4 161,685,236 161,697,633 RGD:1624291
RGD:1600115
G Icmt isoprenylcysteine carboxyl methyltransferase JBrowse link 5 169,475,270 169,482,031 RGD:1624291
G Plce1 phospholipase C, epsilon 1 JBrowse link 1 257,156,023 257,465,440 RGD:1600115
RGD:1624291
G Rabl3 RAB, member of RAS oncogene family-like 3 JBrowse link 11 66,049,635 66,078,669 RGD:1624291
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1624291
RGD:8554560
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:68805
G Syde1 synapse defective Rho GTPase homolog 1 JBrowse link 7 14,037,646 14,043,632 RGD:1624291
regulation of Rho protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07007642.1 RGD:1600115
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:13792537
G Arhgap20 Rho GTPase activating protein 20 JBrowse link 8 56,179,581 56,264,343 RGD:1304008
G Arhgap4 Rho GTPase activating protein 4 JBrowse link X 156,873,094 156,888,762 RGD:632235
G Arhgdia Rho GDP dissociation inhibitor alpha JBrowse link 10 109,754,012 109,757,506 RGD:1624291
G Arhgdib Rho GDP dissociation inhibitor beta JBrowse link 4 170,913,920 170,932,789 RGD:1624291
G Arhgef10 Rho guanine nucleotide exchange factor 10 JBrowse link 16 79,725,629 79,817,065 RGD:1600115
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
RGD:13792537
G Arhgef25 Rho guanine nucleotide exchange factor 25 JBrowse link 7 70,469,304 70,476,633 RGD:1600115
G Arhgef28 Rho guanine nucleotide exchange factor 28 JBrowse link 2 25,738,514 26,011,429 RGD:13792537
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
G Cavin4 caveolae associated protein 4 JBrowse link 5 64,413,005 64,420,849 RGD:1600115
G Cdc42se1 CDC42 small effector 1 JBrowse link 2 196,402,837 196,410,664 RGD:1600115
G Cdc42se2 CDC42 small effector 2 JBrowse link 10 40,054,393 40,122,915 RGD:1600115
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:1582675
G Dlc1 DLC1 Rho GTPase activating protein JBrowse link 16 58,776,489 59,247,752 RGD:1600115
RGD:13792537
G Eps8 epidermal growth factor receptor pathway substrate 8 JBrowse link 4 171,475,155 171,645,620 RGD:13792537
G Eps8l1 EPS8-like 1 JBrowse link 1 72,926,106 72,942,433 RGD:1624291
RGD:13792537
G Eps8l2 EPS8-like 2 JBrowse link 1 214,327,992 214,353,466 RGD:1624291
RGD:13792537
G Eps8l3 EPS8 like 3 JBrowse link 2 210,668,249 210,681,930 RGD:13792537
G Flot1 flotillin 1 JBrowse link 20 3,427,890 3,438,418 RGD:1624291
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:1600115
G Kank1 KN motif and ankyrin repeat domains 1 JBrowse link 1 243,201,073 243,398,531 RGD:1624291
G Kank2 KN motif and ankyrin repeat domains 2 JBrowse link 8 22,792,000 22,821,459 RGD:1600115
RGD:1624291
G LOC100362023 CDC42 small effector 2-like JBrowse link 1 94,988,080 94,988,860 RGD:1600115
G Myo9b myosin IXb JBrowse link 16 19,669,373 19,754,065 RGD:1600115
RGD:1624291
G Ophn1 oligophrenin 1 JBrowse link X 68,185,865 68,579,518 RGD:1624291
G Pdcd10 programmed cell death 10 JBrowse link 2 173,966,701 174,012,730 RGD:1624291
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1600115
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 JBrowse link 2 21,460,041 21,698,937 RGD:1600115
G Stard13 StAR-related lipid transfer domain containing 13 JBrowse link 12 1,023,494 1,418,919 RGD:13792537
G Stard8 StAR-related lipid transfer domain containing 8 JBrowse link X 68,713,157 68,785,046 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    signaling 7531
      signal transduction 6946
        intracellular signal transduction 2594
          regulation of intracellular signal transduction 1694
            regulation of small GTPase mediated signal transduction 235
              modulation by symbiont of host small GTPase mediated signal transduction + 0
              negative regulation of small GTPase mediated signal transduction + 64
              positive regulation of small GTPase mediated signal transduction + 75
              regulation of Ras protein signal transduction + 199
Path 2
Term Annotations click to browse term
  biological_process 19678
    biological regulation 13599
      regulation of biological process 12921
        regulation of cellular process 12405
          signal transduction 6946
            regulation of signal transduction 2971
              regulation of intracellular signal transduction 1694
                regulation of small GTPase mediated signal transduction 235
                  modulation by symbiont of host small GTPase mediated signal transduction + 0
                  negative regulation of small GTPase mediated signal transduction + 64
                  positive regulation of small GTPase mediated signal transduction + 75
                  regulation of Ras protein signal transduction + 199
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.