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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of small GTPase mediated signal transduction
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Accession:GO:0051057 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.
Synonyms:exact_synonym: up regulation of small GTPase mediated signal transduction;   upregulation of small GTPase mediated signal transduction
 narrow_synonym: activation of small GTPase mediated signal transduction;   stimulation of small GTPase mediated signal transduction


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positive regulation of small GTPase mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:2325271
G Bnip2 BCL2 interacting protein 2 JBrowse link 8 76,400,333 76,426,307 RGD:1624291
G Cdon cell adhesion associated, oncogene regulated JBrowse link 8 36,625,757 36,712,091 RGD:1624291
RGD:1600115
G Frmd7 FERM domain containing 7 JBrowse link X 138,095,707 138,149,702 RGD:1624291
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:5686649
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:5686649
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
positive regulation of ARF protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 JBrowse link 9 46,657,444 46,782,545 RGD:1624291
G Mapre2 microtubule-associated protein, RP/EB family, member 2 JBrowse link 18 14,814,149 15,780,290 RGD:1624291
positive regulation of Rac protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 JBrowse link 2 187,964,100 188,022,847 RGD:1624291
G Auts2 activator of transcription and developmental regulator AUTS2 JBrowse link 12 27,155,362 28,252,752 RGD:1624291
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:6907067
G Dynlt1 dynein light chain Tctex-type 1 JBrowse link 1 47,206,892 47,213,785 RGD:8553295
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:1624291
G Rtn4 reticulon 4 JBrowse link 14 114,126,931 114,174,459 RGD:1600115
RGD:1624291
positive regulation of Ras protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arpp19 cAMP-regulated phosphoprotein 19 JBrowse link 8 81,949,577 81,972,054 RGD:625586
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:1624291
G Dgki diacylglycerol kinase, iota JBrowse link 4 64,365,115 64,831,473 RGD:1624291
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:1624291
RGD:13792537
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1582125
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:8553977
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Itpkb inositol-trisphosphate 3-kinase B JBrowse link 13 98,615,287 98,710,426 RGD:1624291
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:1624291
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:8553977
G Mmd2 monocyte to macrophage differentiation-associated 2 JBrowse link 12 14,021,724 14,078,121 RGD:1624291
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1600115
RGD:1624291
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
RGD:1600115
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:1624291
RGD:1600115
G Rasgef1a RasGEF domain family, member 1A JBrowse link 4 150,063,484 150,144,203 RGD:1624291
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:7241548
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:1624291
G Rasgrp4 RAS guanyl releasing protein 4 JBrowse link 1 88,078,350 88,094,331 RGD:1600115
RGD:1624291
G Shoc2 SHOC2 leucine-rich repeat scaffold protein JBrowse link 1 274,700,621 274,751,195 RGD:1600115
RGD:13792537
RGD:1624291
G Stk19 serine/threonine kinase 19 JBrowse link 20 4,317,440 4,517,128 RGD:1624291
positive regulation of Rho protein signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abra actin-binding Rho activating protein JBrowse link 7 80,792,615 80,796,683 RGD:1624291
RGD:13792537
RGD:1600115
G Adgrg1 adhesion G protein-coupled receptor G1 JBrowse link 19 10,423,534 10,460,674 RGD:1600115
RGD:1624291
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:1600115
RGD:1624291
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
G Arhgef3 Rho guanine nucleotide exchange factor 3 JBrowse link 16 2,743,714 3,026,768 RGD:13792537
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:1624291
RGD:1600115
G F11r F11 receptor JBrowse link 13 89,826,272 89,850,151 RGD:1624291
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
RGD:13792537
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:13792537
RGD:1600115
G F2rl2 coagulation factor II (thrombin) receptor-like 2 JBrowse link 2 26,240,385 26,245,533 RGD:13792537
G F2rl3 F2R like thrombin or trypsin receptor 3 JBrowse link 16 18,817,797 18,819,790 RGD:13792537
G Gpr17 G protein-coupled receptor 17 JBrowse link 18 24,733,306 24,739,194 RGD:13792537
G Gpr174 G protein-coupled receptor 174 JBrowse link X 78,358,347 78,399,944 RGD:13792537
G Gpr18 G protein-coupled receptor 18 JBrowse link 15 108,323,157 108,326,907 RGD:13792537
G Gpr35 G protein-coupled receptor 35 JBrowse link 9 100,129,428 100,141,269 RGD:13792537
G Gpr4 G protein-coupled receptor 4 JBrowse link 1 80,125,639 80,136,786 RGD:13792537
RGD:1624291
G Gpr55 G protein-coupled receptor 55 JBrowse link 9 92,961,431 93,011,157 RGD:1624291
RGD:13792537
G Gpr65 G-protein coupled receptor 65 JBrowse link 6 122,248,528 122,256,115 RGD:13792537
G LOC100359656 rCG38062-like JBrowse link X 77,786,566 77,810,066 RGD:13792537
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:1600115
RGD:1624291
G Lpar2 lysophosphatidic acid receptor 2 JBrowse link 16 21,343,313 21,348,913 RGD:1624291
G Lpar4 lysophosphatidic acid receptor 4 JBrowse link X 78,042,859 78,056,347 RGD:13792537
G Lpar6 lysophosphatidic acid receptor 6 JBrowse link 15 55,126,953 55,128,762 RGD:13792537
G Mcf2l MCF.2 cell line derived transforming sequence-like JBrowse link 16 81,839,686 81,986,007 RGD:729022
RGD:1624291
G Net1 neuroepithelial cell transforming 1 JBrowse link 17 69,991,786 70,020,977 RGD:13792537
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:5508741
G P2ry10 P2Y receptor family member 10 JBrowse link X 78,158,729 78,210,413 RGD:13792537
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:10449505
G Prag1 PEAK1 related kinase activating pseudokinase 1 JBrowse link 16 59,666,794 59,730,681 RGD:11555369
G RGD1560455 similar to RIKEN cDNA A630033H20 gene JBrowse link X 78,258,495 78,284,180 RGD:13792537
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1600115
RGD:1624291
G Rtn4r reticulon 4 receptor JBrowse link 11 86,992,665 87,017,091 RGD:1624291
RGD:1600115
G Synpo2l synaptopodin 2-like JBrowse link 15 4,064,706 4,074,151 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    positive regulation of biological process 6506
      positive regulation of signaling 2036
        positive regulation of signal transduction 1625
          positive regulation of intracellular signal transduction 1025
            positive regulation of small GTPase mediated signal transduction 73
              positive regulation of Ras protein signal transduction + 65
Path 2
Term Annotations click to browse term
  biological_process 19576
    biological regulation 13536
      regulation of biological process 12839
        regulation of cellular process 12332
          signal transduction 6929
            intracellular signal transduction 2610
              small GTPase mediated signal transduction 481
                regulation of small GTPase mediated signal transduction 232
                  positive regulation of small GTPase mediated signal transduction 73
                    positive regulation of Ras protein signal transduction + 65
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.