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ONTOLOGY REPORT - ANNOTATIONS


Term:RNA polymerase II preinitiation complex assembly
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Accession:GO:0051123 term browser browse the term
Definition:The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
Synonyms:exact_synonym: RNA polymerase II transcription PIC biosynthesis;   RNA polymerase II transcription PIC formation;   RNA polymerase II transcriptional preinitiation complex assembly;   RNA polymerase II transcriptional preinitiation complex formation


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RNA polymerase II preinitiation complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brf2 BRF2, RNA polymerase III transcription initiation factor subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:69,089,955...69,094,678
Ensembl chr16:69,089,955...69,094,680
JBrowse link
G Dr1 down-regulator of transcription 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:2,463,651...2,475,004
Ensembl chr14:2,463,643...2,474,780
JBrowse link
G Gtf2a2 general transcription factor 2A subunit 2 ISO
IBA
(PMID:7958899), (PMID:8626665)
PMID:21873635
RGD PMID:7958899, PMID:8626665, PMID:21873635 RGD:13792537 NCBI chr 8:76,422,341...76,435,587
Ensembl chr 8:76,422,359...76,435,473
JBrowse link
G Gtf2b general transcription factor IIB IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:3029109), (PMID:8413225), (PMID:9841876)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:3029109, PMID:8413225, PMID:9841876, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 2:248,709,433...248,727,741
Ensembl chr 2:248,715,281...248,727,741
JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 IDA RGD PMID:7929273 RGD:9681417 NCBI chr15:57,942,057...58,068,892
Ensembl chr15:57,942,059...58,068,892
JBrowse link
G LOC100910207 protein Dr1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:1,621,021...1,632,432
Ensembl chr14:1,621,026...1,632,378
JBrowse link
G LOC103695118 transcription initiation factor IIA subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 8:76,422,359...76,435,473 JBrowse link
G Taf11 TATA-box binding protein associated factor 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:7,476,648...7,484,417
Ensembl chr20:7,476,651...7,482,747
JBrowse link
G Taf12 TATA-box binding protein associated factor 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:150,459,701...150,476,521
Ensembl chr 5:150,459,713...150,475,186
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:30,779,149...30,781,297
Ensembl chr18:30,779,150...30,781,292
JBrowse link
G Taf7l TATA-box binding protein associated factor 7-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:105,292,338...105,308,554
Ensembl chr  X:105,292,338...105,308,554
JBrowse link
G Taf7l-ps1 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, pseudogene 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:59,138,768...59,139,910 JBrowse link
G Taf7l2 Taf7l2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:59,138,768...59,139,910 JBrowse link
G Tbp TATA box binding protein ISO (PMID:9841876) RGD PMID:9841876 NCBI chr 1:57,491,381...57,509,335
Ensembl chr 1:57,491,643...57,508,449
JBrowse link
negative regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 ISO (PMID:8006019) RGD PMID:8006019 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Thra thyroid hormone receptor alpha IEA
ISO
GO_REF:0000107
(PMID:8524305)
Ensembl
RGD
PMID:8524305 GO_REF:0000107 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ISO (MGI:MGI:62922|PMID:8215422) RGD PMID:8215422 MGI:MGI:62922 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cand1 cullin-associated and neddylation-dissociated 1 IDA PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chr 7:62,124,362...62,162,451
Ensembl chr 7:62,124,362...62,162,453
JBrowse link
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16891311 RGD:1625706 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Esr1 estrogen receptor 1 IEA
ISO
GO_REF:0000107
(PMID:9841876)
Ensembl
RGD
PMID:9841876 GO_REF:0000107 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO MGI:MGI:2158690 (MGI:MGI:5317044|PMID:21245044) RGD PMID:21245044 MGI:MGI:5317044 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,978,220...84,986,536
Ensembl chr 1:84,978,206...84,986,581
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Tp53 tumor protein p53 ISO (PMID:24289924) RGD PMID:24289924 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Wnt10b Wnt family member 10B ISO (MGI:MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:MGI:3820325 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268
JBrowse link
regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf7ip activating transcription factor 7 interacting protein ISO (PMID:12665582) RGD PMID:12665582 NCBI chr 4:170,476,998...170,563,063
Ensembl chr 4:170,518,673...170,559,532
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          gene expression 6294
            transcription, DNA-templated 3418
              DNA-templated transcription, initiation 124
                transcription initiation from RNA polymerase II promoter 78
                  RNA polymerase II preinitiation complex assembly 29
                    negative regulation of RNA polymerase II transcription preinitiation complex assembly 2
                    positive regulation of RNA polymerase II transcription preinitiation complex assembly 12
                    regulation of RNA polymerase II transcription preinitiation complex assembly + 15
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA biosynthetic process 3477
                  nucleic acid-templated transcription 3463
                    transcription, DNA-templated 3418
                      DNA-templated transcription, initiation 124
                        transcription initiation from RNA polymerase II promoter 78
                          RNA polymerase II preinitiation complex assembly 29
                            negative regulation of RNA polymerase II transcription preinitiation complex assembly 2
                            positive regulation of RNA polymerase II transcription preinitiation complex assembly 12
                            regulation of RNA polymerase II transcription preinitiation complex assembly + 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.