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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic growth at neuromuscular junction
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Accession:GO:0051124 term browser browse the term
Definition:The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.
Synonyms:related_synonym: cholinergic synaptogenesis


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synaptic growth at neuromuscular junction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO MGI:MGI:88047 (MGI:MGI:3577153|PMID:15689559) RGD PMID:15689559 MGI:MGI:3577153 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G LOC103690160 SH3 and multiple ankyrin repeat domains protein 2-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:215,208,591...215,246,638
Ensembl chr 1:215,214,853...215,241,723
JBrowse link
G Lrp4 LDL receptor related protein 4 ISS
ISO
GO_REF:0000024
MGI:MGI:2661383|MGI:MGI:3580702 (MGI:MGI:3703100|PMID:17119023), (MGI:MGI:3829843|PMID:18957220)
UniProt
RGD
PMID:17119023, PMID:18957220 GO_REF:0000024, MGI:MGI:3703100, MGI:MGI:3829843 NCBI chr 3:80,362,643...80,416,684
Ensembl chr 3:80,362,858...80,416,679
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,297,137...100,344,377
Ensembl chr 1:100,297,152...100,344,377
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:217,149,156...217,593,950
Ensembl chr 1:217,151,166...217,592,763
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
negative regulation of synaptic growth at neuromuscular junction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsk3b glycogen synthase kinase 3 beta IMP PMID:25764078 CACAO PMID:25764078 RGD:15023478 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
positive regulation of synaptic growth at neuromuscular junction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrn agrin ISO
ISS
(MGI:MGI:1337916|PMID:10402191)
GO_REF:0000024
RGD
UniProt
PMID:10402191 GO_REF:0000024, MGI:MGI:1337916 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IMP PMID:25764078 CACAO PMID:25764078 RGD:15023478 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Musk muscle associated receptor tyrosine kinase IMP RGD PMID:14749715 RGD:2317108 NCBI chr 5:75,392,790...75,498,694
Ensembl chr 5:75,392,790...75,498,694
JBrowse link
regulation of synaptic growth at neuromuscular junction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrn agrin ISO
IEA
MGI:MGI:2136176 (MGI:MGI:1891559|PMID:11018052)
GO_REF:0000107
RGD
Ensembl
PMID:11018052 GO_REF:0000107, MGI:MGI:1891559 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase ISO
IEA
MGI:MGI:1857733 (MGI:MGI:4431306|PMID:20053883)
GO_REF:0000107
RGD
Ensembl
PMID:20053883 GO_REF:0000107, MGI:MGI:4431306 NCBI chr16:7,626,380...7,681,621
Ensembl chr16:7,627,603...7,681,576
JBrowse link
G Musk muscle associated receptor tyrosine kinase ISO
ISS
MGI:MGI:1929066 (MGI:MGI:80613|PMID:8653786)
GO_REF:0000024
RGD
UniProt
PMID:8653786 GO_REF:0000024, MGI:MGI:80613 NCBI chr 5:75,392,790...75,498,694
Ensembl chr 5:75,392,790...75,498,694
JBrowse link
G Six1 SIX homeobox 1 ISO MGI:MGI:106034 (MGI:MGI:5298278|PMID:21884692) RGD PMID:21884692 MGI:MGI:5298278 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
G Six4 SIX homeobox 4 ISO MGI:MGI:102780 (MGI:MGI:5298278|PMID:21884692) RGD PMID:21884692 MGI:MGI:5298278 NCBI chr 6:95,984,868...95,999,709
Ensembl chr 6:95,984,868...95,998,529
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      developmental growth 818
        synaptic growth at neuromuscular junction 12
          negative regulation of synaptic growth at neuromuscular junction 1
          positive regulation of synaptic growth at neuromuscular junction 3
          regulation of synaptic growth at neuromuscular junction + 6
Path 2
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component biogenesis 3276
          cellular component assembly 2967
            cell junction assembly 445
              synapse assembly 191
                synaptic growth at neuromuscular junction 12
                  negative regulation of synaptic growth at neuromuscular junction 1
                  positive regulation of synaptic growth at neuromuscular junction 3
                  regulation of synaptic growth at neuromuscular junction + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.