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ONTOLOGY REPORT - ANNOTATIONS


Term:smooth muscle cell differentiation
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Accession:GO:0051145 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
Synonyms:exact_synonym: nonstriated muscle cell differentiation


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smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:1624291
RGD:1600115
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:1624291
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Foxf1 forkhead box F1 JBrowse link 19 53,012,306 53,016,100 RGD:1624291
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1624291
RGD:1600115
G Mrtfa myocardin related transcription factor A JBrowse link 7 122,233,196 122,403,661 RGD:1624291
RGD:13792537
G Mrtfb myocardin related transcription factor B JBrowse link 10 1,151,163 1,273,269 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1299359
RGD:13792537
RGD:1624291
G Nfatc3 nuclear factor of activated T-cells 3 JBrowse link 19 38,039,542 38,114,003 RGD:1624291
G Nfatc4 nuclear factor of activated T-cells 4 JBrowse link 15 34,493,163 34,502,238 RGD:1624291
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:1624291
G Tbx18 T-box transcription factor 18 JBrowse link 8 95,359,354 95,387,363 RGD:1624291
G Tmem204 transmembrane protein 204 JBrowse link 10 14,417,608 14,446,272 RGD:1624291
RGD:13792537
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
RGD:1600115
G Wnt7b Wnt family member 7B JBrowse link 7 126,423,418 126,465,724 RGD:1624291
aortic smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 JBrowse link 1 244,615,811 244,783,736 RGD:1624291
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:1624291
cardiac vascular smooth muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1600115
RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
G Mir143 microRNA 143 JBrowse link 18 56,971,273 56,971,377 RGD:1624291
G Mir145 microRNA 145 JBrowse link 18 56,969,907 56,969,994 RGD:1624291
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
enteric smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:1624291
kidney smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tshz3 teashirt zinc finger homeobox 3 JBrowse link 1 92,703,180 92,775,020 RGD:1624291
negative regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:13210556
negative regulation of kidney smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
negative regulation of smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd17 ankyrin repeat domain 17 JBrowse link 14 19,291,025 19,431,521 RGD:1624291
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:1624291
RGD:1600115
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:1624291
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1600115
RGD:1624291
G Med28 mediator complex subunit 28 JBrowse link 14 70,089,225 70,098,021 RGD:1624291
G Prdm6 PR/SET domain 6 JBrowse link 18 48,433,747 48,538,834 RGD:1624291
G Rbpms2 RNA binding protein, mRNA processing factor 2 JBrowse link 8 71,165,375 71,200,299 RGD:1624291
RGD:13792537
G Rcan1 regulator of calcineurin 1 JBrowse link 11 32,539,689 32,620,274 RGD:1581653
negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
RGD:1600115
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1600115
RGD:1624291
negative regulation of ureter smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
negative regulation of vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfatc1 nuclear factor of activated T-cells 1 JBrowse link 18 77,203,517 77,322,690 RGD:1624291
G Nfatc2 nuclear factor of activated T-cells 2 JBrowse link 3 165,241,750 165,374,644 RGD:1624291
G Nfatc3 nuclear factor of activated T-cells 3 JBrowse link 19 38,039,542 38,114,003 RGD:1624291
G Pdcd4 programmed cell death 4 JBrowse link 1 274,616,625 274,648,204 RGD:1624291
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:1600115
negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1600115
RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:13601993
positive regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cth cystathionine gamma-lyase JBrowse link 2 264,266,959 264,293,040 RGD:1624291
positive regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1624291
RGD:1600115
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:8554320
positive regulation of kidney smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
positive regulation of smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Olfm2 olfactomedin 2 JBrowse link 8 21,684,307 21,762,000 RGD:1624291
RGD:1600115
G Pias1 protein inhibitor of activated STAT, 1 JBrowse link 8 67,771,720 67,869,015 RGD:2303115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 JBrowse link 4 7,076,710 7,108,334 RGD:9586362
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:8553354
G Tshz3 teashirt zinc finger homeobox 3 JBrowse link 1 92,703,180 92,775,020 RGD:1624291
positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itga8 integrin subunit alpha 8 JBrowse link 17 79,321,893 79,676,927 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
RGD:8554320
G Npnt nephronectin JBrowse link 2 238,001,767 238,068,886 RGD:1624291
RGD:1600115
positive regulation of ureter smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
positive regulation of vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:1624291
positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1624291
regulation of aortic smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sdc4 syndecan 4 JBrowse link 3 160,872,503 160,891,190 RGD:11079193
regulation of smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 1 21,613,148 21,684,483 RGD:1299488
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1299358
G Zeb1 zinc finger E-box binding homeobox 1 JBrowse link 17 54,656,627 54,714,920 RGD:1624291
RGD:1600115
ureter smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Six1 SIX homeobox 1 JBrowse link 6 95,929,060 95,934,296 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
G Tshz3 teashirt zinc finger homeobox 3 JBrowse link 1 92,703,180 92,775,020 RGD:1624291
vascular smooth muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:1624291
RGD:1600115
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Ramp2 receptor activity modifying protein 2 JBrowse link 10 89,166,170 89,168,962 RGD:1624291
RGD:1600115
G Sgcb sarcoglycan, beta JBrowse link 14 37,113,194 37,128,623 RGD:1624291
vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Epc1 enhancer of polycomb homolog 1 JBrowse link 17 57,303,968 57,394,975 RGD:9587795
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:1624291

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.