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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of muscle cell differentiation
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Accession:GO:0051148 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.
Synonyms:exact_synonym: down regulation of muscle cell differentiation;   downregulation of muscle cell differentiation
 narrow_synonym: inhibition of muscle cell differentiation


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negative regulation of muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptbp1 polypyrimidine tract binding protein 1 JBrowse link 7 12,663,965 12,673,723 RGD:1624291
RGD:1600115
G Tnpo2 transportin 2 JBrowse link 19 26,149,671 26,171,812 RGD:1624291
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1600115
RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link 7 60,128,506 60,210,482 RGD:1624291
G Fzd7 frizzled class receptor 7 JBrowse link 9 66,305,731 66,308,550 RGD:1624291
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:1624291
G Sox6 SRY-box transcription factor 6 JBrowse link 1 185,631,702 186,186,192 RGD:1624291
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
negative regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:13210556
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:6784534
G Ctdp1 CTD phosphatase subunit 1 JBrowse link 18 76,922,913 76,985,095 RGD:9686371
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:11561912
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:10449133
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
G Mir451a microRNA 451a JBrowse link 10 65,291,204 65,291,275 RGD:11558015
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:11533929
G Pi16 peptidase inhibitor 16 JBrowse link 20 6,923,176 6,932,786 RGD:1624291
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:5687133
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:13524577
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:7207376
G Tomm70 translocase of outer mitochondrial membrane 70 JBrowse link 11 45,477,053 45,511,409 RGD:13464131
G Yy1 YY1 transcription factor JBrowse link 6 132,702,443 132,726,848 RGD:9588273
negative regulation of kidney smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
negative regulation of myoblast fusion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:1624291
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:1624291
G Il36g interleukin 36, gamma JBrowse link 3 1,285,658 1,291,836 RGD:1624291
negative regulation of myotube differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd2 ankyrin repeat domain 2 JBrowse link 1 261,281,859 261,291,307 RGD:1624291
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:1580249
G Bhlha15 basic helix-loop-helix family, member a15 JBrowse link 12 12,403,385 12,409,103 RGD:1624291
RGD:1600115
G Bhlhe41 basic helix-loop-helix family, member e41 JBrowse link 4 180,230,742 180,235,138 RGD:1624291
RGD:1600115
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:1624291
RGD:1600115
G Daxx death-domain associated protein JBrowse link 20 5,480,103 5,485,962 RGD:9587764
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:1624291
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:1624291
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:1624291
G Hdac5 histone deacetylase 5 JBrowse link 10 90,140,183 90,169,853 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
G Plpp7 phospholipid phosphatase 7 (inactive) JBrowse link 3 11,114,551 11,130,427 RGD:1624291
G Tmem119 transmembrane protein 119 JBrowse link 12 48,598,498 48,605,704 RGD:1624291
G Trim72 tripartite motif containing 72 JBrowse link 1 199,450,042 199,457,902 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
negative regulation of sarcomere organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:13204833
negative regulation of smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd17 ankyrin repeat domain 17 JBrowse link 14 19,291,025 19,431,521 RGD:1624291
G Ereg epiregulin JBrowse link 14 18,577,620 18,591,395 RGD:1624291
RGD:1600115
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:1624291
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:1600115
RGD:1624291
G Med28 mediator complex subunit 28 JBrowse link 14 70,089,225 70,098,021 RGD:1624291
G Prdm6 PR/SET domain 6 JBrowse link 18 48,433,747 48,538,834 RGD:1624291
G Rbpms2 RNA binding protein, mRNA processing factor 2 JBrowse link 8 71,165,375 71,200,299 RGD:1624291
RGD:13792537
G Rcan1 regulator of calcineurin 1 JBrowse link 11 32,539,689 32,620,274 RGD:1581653
negative regulation of striated muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:1624291
G LOC100912427 nuclease-sensitive element-binding protein 1-like JBrowse link 1 186,635,408 186,641,503 RGD:1624291
G Msx1 msh homeobox 1 JBrowse link 14 77,712,262 77,716,061 RGD:1624291
G Ybx1 Y box binding protein 1 JBrowse link 5 138,319,754 138,336,721 RGD:1600115
negative regulation of ureter smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
RGD:1624291
negative regulation of vascular smooth muscle cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfatc1 nuclear factor of activated T-cells 1 JBrowse link 18 77,203,517 77,322,690 RGD:1624291
G Nfatc2 nuclear factor of activated T-cells 2 JBrowse link 3 165,241,750 165,374,644 RGD:1624291
G Nfatc3 nuclear factor of activated T-cells 3 JBrowse link 19 38,039,542 38,114,003 RGD:1624291
G Pdcd4 programmed cell death 4 JBrowse link 1 274,616,625 274,648,204 RGD:1624291
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:1600115
negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:1600115
RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:13601993

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19335
    negative regulation of biological process 5553
      negative regulation of developmental process 1096
        negative regulation of cell differentiation 811
          negative regulation of muscle cell differentiation 64
            negative regulation of smooth muscle cell differentiation + 17
            negative regulation of striated muscle cell differentiation + 45
Path 2
Term Annotations click to browse term
  biological_process 19335
    developmental process 6638
      cellular developmental process 4415
        cell differentiation 4195
          muscle cell differentiation 409
            regulation of muscle cell differentiation 168
              negative regulation of muscle cell differentiation 64
                negative regulation of smooth muscle cell differentiation + 17
                negative regulation of striated muscle cell differentiation + 45
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.