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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of release of sequestered calcium ion into cytosol
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Accession:GO:0051280 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms:exact_synonym: down regulation of release of sequestered calcium ion into cytosol;   downregulation of release of sequestered calcium ion into cytosol;   negative regulation of cytosolic release of sequestered calcium ion (Ca2+);   negative regulation of cytosolic release of stored calcium ion (Ca2+);   negative regulation of release of stored calcium ion (Ca2+) into cytosol
 narrow_synonym: inhibition of release of sequestered calcium ion into cytosol
 broad_synonym: negative regulation of calcium ion (Ca2+) mobilization;   negative regulation of calcium mobilization;   negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+);   negative regulation of cytoplasmic release of stored calcium ion (Ca2+);   negative regulation of release of sequestered calcium ion (Ca2+);   negative regulation of release of sequestered calcium ion into cytoplasm;   negative regulation of release of stored calcium ion (Ca2+);   negative regulation of release of stored calcium ion (Ca2+) into cytoplasm


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negative regulation of release of sequestered calcium ion into cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcrl5 Fc receptor-like 5 JBrowse link 2 186,776,466 186,797,900 RGD:1624291
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
G Ntsr1 neurotensin receptor 1 JBrowse link 3 175,982,313 176,046,345 RGD:727385
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:7206836
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:731229
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:731229
G Trdn triadin JBrowse link 1 25,403,390 25,787,664 RGD:7327230
negative regulation of ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1624291
RGD:1600115
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1600115
RGD:1624291
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1624291
RGD:1600115
G Casq2 calsequestrin 2 JBrowse link 2 204,512,361 204,568,643 RGD:1624291
RGD:1600115
RGD:2314601
G Clic2 chloride intracellular channel 2 JBrowse link 20 295,338 310,363 RGD:1624291
RGD:1600115
G Fkbp1a FKBP prolyl isomerase 1A JBrowse link 3 147,042,944 147,062,725 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
RGD:1600115
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1624291
RGD:1600115
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
RGD:1600115
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    cellular process 16091
      negative regulation of cellular process 4791
        negative regulation of calcium ion transport into cytosol 21
          negative regulation of release of sequestered calcium ion into cytosol 17
            negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
            negative regulation of ryanodine-sensitive calcium-release channel activity 11
Path 2
Term Annotations click to browse term
  biological_process 17941
    biological regulation 12628
      regulation of biological quality 4130
        homeostatic process 1966
          chemical homeostasis 1258
            ion homeostasis 841
              cellular ion homeostasis 690
                cellular cation homeostasis 677
                  cellular metal ion homeostasis 618
                    cellular calcium ion homeostasis 506
                      regulation of cytosolic calcium ion concentration 410
                        positive regulation of cytosolic calcium ion concentration 355
                          calcium ion transport into cytosol 176
                            calcium ion transmembrane import into cytosol 152
                              release of sequestered calcium ion into cytosol 133
                                regulation of release of sequestered calcium ion into cytosol 87
                                  negative regulation of release of sequestered calcium ion into cytosol 17
                                    negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0
                                    negative regulation of ryanodine-sensitive calcium-release channel activity 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.