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ONTOLOGY REPORT - ANNOTATIONS


Term:centrosome duplication
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Accession:GO:0051298 term browser browse the term
Definition:The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Synonyms:exact_synonym: centrosome replication


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centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARHGEF10 Rho guanine nucleotide exchange factor 10 JBrowse link 8 1,747,801 1,862,917 RGD:9068941
G BRCA2 BRCA2 DNA repair associated JBrowse link 13 32,009,039 32,092,463 RGD:9068941
G BRSK1 BR serine/threonine kinase 1 JBrowse link 19 61,021,479 61,046,190 RGD:9068941
G CCP110 centriolar coiled-coil protein 110 JBrowse link 16 19,624,708 19,654,131 RGD:9068941
G CDK2 cyclin dependent kinase 2 JBrowse link 12 33,189,934 33,195,945 RGD:9068941
G CEP152 centrosomal protein 152 JBrowse link 15 46,011,447 46,084,233 RGD:9068941
G CEP192 centrosomal protein 192 JBrowse link 18 16,327,525 16,460,678 RGD:9068941
G CHORDC1 cysteine and histidine rich domain containing 1 JBrowse link 11 88,660,038 88,689,535 RGD:9068941
G CKAP5 cytoskeleton associated protein 5 JBrowse link 11 47,252,269 47,353,770 RGD:9068941
G NDE1 nudE neurodevelopment protein 1 JBrowse link 16 15,948,881 16,004,208 RGD:9068941
G PKD2 polycystin 2, transient receptor potential cation channel JBrowse link 4 91,019,739 91,088,858 RGD:9068941
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 2A 11,316,755 11,478,986 RGD:9068941
G SAC3D1 SAC3 domain containing 1 JBrowse link 11 63,737,026 63,740,463 RGD:9068941
G SASS6 SAS-6 centriolar assembly protein JBrowse link 1 101,457,559 101,506,348 RGD:9068941
G STIL STIL centriolar assembly protein JBrowse link 1 48,072,728 48,137,071 RGD:9068941
G USP33 ubiquitin specific peptidase 33 JBrowse link 1 78,999,339 79,065,088 RGD:9068941
centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2CD3 C2 domain containing 3 centriole elongation regulator JBrowse link 11 72,392,606 72,551,620 RGD:9068941
G CENPJ centromere protein J JBrowse link 13 24,464,045 24,503,432 RGD:9068941
centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCP110 centriolar coiled-coil protein 110 JBrowse link 16 19,624,708 19,654,131 RGD:9068941
G CDK2 cyclin dependent kinase 2 JBrowse link 12 33,189,934 33,195,945 RGD:9068941
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 JBrowse link 9 119,867,654 120,055,608 RGD:9068941
G CENPJ centromere protein J JBrowse link 13 24,464,045 24,503,432 RGD:9068941
G CEP135 centrosomal protein 135 JBrowse link 4 74,463,689 74,547,795 RGD:9068941
G CEP152 centrosomal protein 152 JBrowse link 15 46,011,447 46,084,233 RGD:9068941
G CEP63 centrosomal protein 63 JBrowse link 3 139,003,890 139,115,026 RGD:9068941
G CEP72 centrosomal protein 72 JBrowse link 5 733,647 782,630 RGD:9068941
G CETN1 centrin 1 JBrowse link 18 17,385,106 17,386,772 RGD:9068941
G CETN2 centrin 2 JBrowse link X 152,320,893 152,324,362 RGD:9068941
G CNTROB centrobin, centriole duplication and spindle assembly protein JBrowse link 17 7,953,617 7,970,148 RGD:9068941
G DEUP1 deuterosome assembly protein 1 JBrowse link 11 91,846,096 91,946,993 RGD:9068941
G KIAA0753 KIAA0753 ortholog JBrowse link 17 6,603,983 6,666,231 RGD:9068941
G OFD1 OFD1 centriole and centriolar satellite protein JBrowse link X 13,630,006 13,669,285 RGD:9068941
G PLK4 polo like kinase 4 JBrowse link 4 131,349,562 131,367,832 RGD:9068941
G RTTN rotatin JBrowse link 18 66,674,250 66,874,390 RGD:9068941
G SASS6 SAS-6 centriolar assembly protein JBrowse link 1 101,457,559 101,506,348 RGD:9068941
G WDR62 WD repeat domain 62 JBrowse link 19 41,721,289 41,777,038 RGD:9068941
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHMP2A charged multivesicular body protein 2A JBrowse link 19 64,377,986 64,381,641 RGD:9068941
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRCA1 BRCA1 DNA repair associated JBrowse link 17 14,429,601 14,506,815 RGD:9068941
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 JBrowse link 9 119,867,654 120,055,608 RGD:9068941
G KAT2A lysine acetyltransferase 2A JBrowse link 17 15,416,075 15,424,197 RGD:9068941
G KAT2B lysine acetyltransferase 2B JBrowse link 3 20,286,080 20,399,970 RGD:9068941
G MDM1 Mdm1 nuclear protein JBrowse link 12 68,588,541 68,626,359 RGD:9068941
G TRIM37 tripartite motif containing 37 JBrowse link 17 57,904,813 58,027,160 RGD:9068941
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCNF cyclin F JBrowse link 16 2,526,035 2,558,265 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 5 173,490,197 173,510,657 RGD:9068941
G NUBP1 nucleotide binding protein 1 JBrowse link 16 10,906,347 10,931,799 RGD:9068941
G TMEM67 transmembrane protein 67 JBrowse link 8 92,324,402 92,387,437 RGD:9068941
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPJ centromere protein J JBrowse link 13 24,464,045 24,503,432 RGD:9068941
G CEP120 centrosomal protein 120 JBrowse link 5 124,514,996 124,593,259 RGD:9068941
G CEP295 centrosomal protein 295 JBrowse link 11 92,170,720 92,239,237 RGD:9068941
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 18 60,062,080 60,095,109 RGD:9068941
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NUP62 nucleoporin 62 JBrowse link 19 55,835,593 55,858,165 RGD:9068941
G PLK4 polo like kinase 4 JBrowse link 4 131,349,562 131,367,832 RGD:9068941
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP120 centrosomal protein 120 JBrowse link 5 124,514,996 124,593,259 RGD:9068941
G CEP295 centrosomal protein 295 JBrowse link 11 92,170,720 92,239,237 RGD:9068941
G POC1A POC1 centriolar protein A JBrowse link 3 53,245,162 53,324,579 RGD:9068941
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 2A 11,316,755 11,478,986 RGD:9068941
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALMS1 ALMS1 centrosome and basal body associated protein JBrowse link 2A 74,926,650 75,158,734 RGD:9068941
G C10H10orf90 chromosome 10 C10orf90 homolog JBrowse link 10 127,258,584 127,505,349 RGD:9068941
G CENPJ centromere protein J JBrowse link 13 24,464,045 24,503,432 RGD:9068941
G CEP295 centrosomal protein 295 JBrowse link 11 92,170,720 92,239,237 RGD:9068941
G CEP295NL CEP295 N-terminal like JBrowse link 17 78,512,245 78,524,447 RGD:9068941
G CEP76 centrosomal protein 76 JBrowse link 18 16,735,624 16,765,750 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 5 173,490,197 173,510,657 RGD:9068941
G PLK2 polo like kinase 2 JBrowse link 5 57,178,503 57,184,793 RGD:9068941
G SPICE1 spindle and centriole associated protein 1 JBrowse link 3 117,507,941 117,579,180 RGD:9068941
G STIL STIL centriolar assembly protein JBrowse link 1 48,072,728 48,137,071 RGD:9068941
regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP131 centrosomal protein 131 JBrowse link 17 81,343,396 81,376,891 RGD:9068941
G CHMP1A charged multivesicular body protein 1A JBrowse link 16 90,003,892 90,017,653 RGD:9068941
G CHMP1B charged multivesicular body protein 1B JBrowse link 18 4,716,131 4,719,173 RGD:9068941
G CHMP2A charged multivesicular body protein 2A JBrowse link 19 64,377,986 64,381,641 RGD:9068941
G CHMP2B charged multivesicular body protein 2B JBrowse link 3 89,471,993 89,500,127 RGD:9068941
G CHMP3 charged multivesicular body protein 3 JBrowse link 2A 88,105,216 88,224,003 RGD:9068941
G CHMP4B charged multivesicular body protein 4B JBrowse link 20 31,237,881 31,286,065 RGD:9068941
G CHMP4C charged multivesicular body protein 4C JBrowse link 8 79,879,823 79,906,859 RGD:9068941
G CHMP5 charged multivesicular body protein 5 JBrowse link 9 33,851,377 33,867,942 RGD:9068941
G CHORDC1 cysteine and histidine rich domain containing 1 JBrowse link 11 88,660,038 88,689,535 RGD:9068941
G FBXW5 F-box and WD repeat domain containing 5 JBrowse link 9 136,969,957 136,973,945 RGD:9068941
G GEN1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 2A 17,861,948 17,892,048 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 5 173,490,197 173,510,657 RGD:9068941
G PDCD6IP programmed cell death 6 interacting protein JBrowse link 3 34,016,152 34,093,631 RGD:9068941
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 6 52,435,455 52,903,309 RGD:9068941
G RAB6C RAB6C, member RAS oncogene family JBrowse link 2B 130,642,867 130,644,070 RGD:9068941
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 18 60,062,080 60,095,109 RGD:9068941
G XPO1 exportin 1 JBrowse link 2A 62,698,935 62,759,059 RGD:9068941
G XRCC3 X-ray repair cross complementing 3 JBrowse link 14 104,131,908 104,146,133 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15679
    cellular process 14373
      cell cycle process 1335
        centrosome duplication 67
          centriole replication + 37
          negative regulation of centrosome duplication + 11
          positive regulation of centrosome duplication + 8
          regulation of centrosome duplication + 42
Path 2
Term Annotations click to browse term
  biological_process 15679
    cellular component organization or biogenesis 6210
      cellular component organization 6027
        organelle organization 3759
          cytoskeleton organization 1304
            microtubule cytoskeleton organization 554
              microtubule organizing center organization 134
                centrosome cycle 125
                  centrosome duplication 67
                    centriole replication + 37
                    negative regulation of centrosome duplication + 11
                    positive regulation of centrosome duplication + 8
                    regulation of centrosome duplication + 42
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.