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ONTOLOGY REPORT - ANNOTATIONS


Term:centrosome duplication
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Accession:GO:0051298 term browser browse the term
Definition:The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Synonyms:exact_synonym: centrosome replication


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centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef10 Rho guanine nucleotide exchange factor 10 JBrowse link NW_004955403 57,820,003 57,907,324 RGD:9068941
G Brca2 BRCA2 DNA repair associated JBrowse link NW_004955431 13,449,287 13,526,878 RGD:9068941
G Brsk1 BR serine/threonine kinase 1 JBrowse link NW_004955567 924,728 943,092 RGD:9068941
G Ccp110 centriolar coiled-coil protein 110 JBrowse link NW_004955442 3,223,549 3,261,437 RGD:9068941
G Cdk2 cyclin dependent kinase 2 JBrowse link NW_004955458 3,555,603 3,561,063 RGD:9068941
G Cep152 centrosomal protein 152 JBrowse link NW_004955409 5,121,332 5,210,729 RGD:9068941
G Cep192 centrosomal protein 192 JBrowse link NW_004955402 604,605 675,179 RGD:9068941
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link NW_004955414 3,699,652 3,717,200 RGD:9068941
G Ckap5 cytoskeleton associated protein 5 JBrowse link NW_004955422 1,266,686 1,354,323 RGD:9068941
G Nde1 nudE neurodevelopment protein 1 JBrowse link NW_004955442 495,704 530,296 RGD:9068941
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link NW_004955474 1,831,221 1,868,170 RGD:9068941
G Rock2 Rho associated coiled-coil containing protein kinase 2 JBrowse link NW_004955487 5,856,190 5,972,408 RGD:9068941
G Sac3d1 SAC3 domain containing 1 JBrowse link NW_004955422 20,146,359 20,149,152 RGD:9068941
G Sass6 SAS-6 centriolar assembly protein JBrowse link NW_004955435 4,832,284 4,876,077 RGD:9068941
G Stil STIL centriolar assembly protein JBrowse link NW_004955464 11,213,265 11,288,648 RGD:9068941
G Usp33 ubiquitin specific peptidase 33 JBrowse link NW_004955423 15,424,349 15,469,344 RGD:9068941
centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2cd3 C2 domain containing 3 centriole elongation regulator JBrowse link NW_004955414 17,444,299 17,557,912 RGD:9068941
G Cenpj centromere protein J JBrowse link NW_004955497 432,595 497,335 RGD:9068941
centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccp110 centriolar coiled-coil protein 110 JBrowse link NW_004955442 3,223,549 3,261,437 RGD:9068941
G Cdk2 cyclin dependent kinase 2 JBrowse link NW_004955458 3,555,603 3,561,063 RGD:9068941
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link NW_004955419 7,412,177 7,606,883 RGD:9068941
G Cenpj centromere protein J JBrowse link NW_004955497 432,595 497,335 RGD:9068941
G Cep135 centrosomal protein 135 JBrowse link NW_004955447 14,934,334 15,004,077 RGD:9068941
G Cep152 centrosomal protein 152 JBrowse link NW_004955409 5,121,332 5,210,729 RGD:9068941
G Cep63 centrosomal protein 63 JBrowse link NW_004955501 4,032,281 4,095,990 RGD:9068941
G Cep72 centrosomal protein 72 JBrowse link NW_004955504 305,181 335,791 RGD:9068941
G Cetn1 centrin 1 JBrowse link NW_004955402 9,381,400 9,382,158 RGD:9068941
G Cetn2 centrin 2 JBrowse link NW_004955498 8,131,356 8,135,751 RGD:9068941
G Cntrob centrobin, centriole duplication and spindle assembly protein JBrowse link NW_004955467 8,993,528 9,010,829 RGD:9068941
G Deup1 deuterosome assembly protein 1 JBrowse link NW_004955414 1,062,968 1,126,698 RGD:9068941
G Kiaa0753 KIAA0753 ortholog JBrowse link NW_004955467 12,074,413 12,144,672 RGD:9068941
G Ofd1 OFD1 centriole and centriolar satellite protein JBrowse link NW_004955519 4,433,747 4,470,842 RGD:9068941
G Plk4 polo like kinase 4 JBrowse link NW_004955428 13,548,485 13,566,786 RGD:9068941
G Rttn rotatin JBrowse link NW_004955402 53,600,985 53,753,218 RGD:9068941
G Sass6 SAS-6 centriolar assembly protein JBrowse link NW_004955435 4,832,284 4,876,077 RGD:9068941
G Wdr62 WD repeat domain 62 JBrowse link NW_004955468 2,504,181 2,545,982 RGD:9068941
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chmp2a charged multivesicular body protein 2A JBrowse link NW_004955584 1,156,828 1,160,056 RGD:9068941
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca1 BRCA1 DNA repair associated JBrowse link NW_004955451 16,819,463 16,870,780 RGD:9068941
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link NW_004955419 7,412,177 7,606,883 RGD:9068941
G Kat2a lysine acetyltransferase 2A JBrowse link NW_004955451 16,192,228 16,197,103 RGD:9068941
G Kat2b lysine acetyltransferase 2B JBrowse link NW_004955430 12,109,493 12,196,102 RGD:9068941
G Mdm1 Mdm1 nuclear protein JBrowse link NW_004955458 14,789,842 14,823,117 RGD:9068941
G Trim37 tripartite motif containing 37 JBrowse link NW_004955451 3,839,757 4,014,178 RGD:9068941
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnf cyclin F JBrowse link NW_004955442 14,864,935 14,890,802 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004955408 24,151,070 24,218,783 RGD:9068941
G Nubp1 nucleotide binding protein 1 JBrowse link NW_004955442 7,717,422 7,732,496 RGD:9068941
G Tmem67 transmembrane protein 67 JBrowse link NW_004955417 10,097,488 10,137,959 RGD:9068941
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpj centromere protein J JBrowse link NW_004955497 432,595 497,335 RGD:9068941
G Cep120 centrosomal protein 120 JBrowse link NW_004955521 1,452,514 1,504,763 RGD:9068941
G Cep295 centrosomal protein 295 JBrowse link NW_004955414 806,238 860,273 RGD:9068941
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link NW_004955402 47,154,350 47,183,979 RGD:9068941
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nup62 nucleoporin 62 JBrowse link NW_004955559 1,012,919 1,033,465 RGD:9068941
G Plk4 polo like kinase 4 JBrowse link NW_004955428 13,548,485 13,566,786 RGD:9068941
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep120 centrosomal protein 120 JBrowse link NW_004955521 1,452,514 1,504,763 RGD:9068941
G Cep295 centrosomal protein 295 JBrowse link NW_004955414 806,238 860,273 RGD:9068941
G Poc1a POC1 centriolar protein A JBrowse link NW_004955532 3,707,680 3,790,565 RGD:9068941
G Rock2 Rho associated coiled-coil containing protein kinase 2 JBrowse link NW_004955487 5,856,190 5,972,408 RGD:9068941
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alms1 ALMS1 centrosome and basal body associated protein JBrowse link NW_004955424 12,130,496 12,258,684 RGD:9068941
G Cenpj centromere protein J JBrowse link NW_004955497 432,595 497,335 RGD:9068941
G Cep295 centrosomal protein 295 JBrowse link NW_004955414 806,238 860,273 RGD:9068941
G Cep295nl CEP295 N-terminal like JBrowse link NW_004955506 3,780,240 3,791,540 RGD:9068941
G Cep76 centrosomal protein 76 JBrowse link NW_004955402 870,090 888,577 RGD:9068941
G LOC102012090 chromosome unknown open reading frame, human C10orf90 JBrowse link NW_004955477 4,299,277 4,510,702 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004955408 24,151,070 24,218,783 RGD:9068941
G Plk2 polo like kinase 2 JBrowse link NW_004955446 9,671,090 9,676,956 RGD:9068941
G Spice1 spindle and centriole associated protein 1 JBrowse link NW_004955427 13,584,841 13,626,656 RGD:9068941
G Stil STIL centriolar assembly protein JBrowse link NW_004955464 11,213,265 11,288,648 RGD:9068941
regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep131 centrosomal protein 131 JBrowse link NW_004955506 1,783,717 1,809,665 RGD:9068941
G Chmp1a charged multivesicular body protein 1A JBrowse link NW_004955541 3,216,972 3,223,636 RGD:9068941
G Chmp1b charged multivesicular body protein 1B JBrowse link NW_004955402 1,196,912 1,199,480 RGD:9068941
G Chmp2a charged multivesicular body protein 2A JBrowse link NW_004955584 1,156,828 1,160,056 RGD:9068941
G Chmp2b charged multivesicular body protein 2B JBrowse link NW_004955407 6,014,478 6,047,916 RGD:9068941
G Chmp4b charged multivesicular body protein 4B JBrowse link NW_004955422 27,482,239 27,526,798 RGD:9068941
G Chmp4c charged multivesicular body protein 4C JBrowse link NW_004955417 96,674 135,601 RGD:9068941
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link NW_004955414 3,699,652 3,717,200 RGD:9068941
G Fbxw5 F-box and WD repeat domain containing 5 JBrowse link NW_004955513 4,993,161 4,996,922 RGD:9068941
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link NW_004955469 552,850 590,792 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004955408 24,151,070 24,218,783 RGD:9068941
G Pdcd6ip programmed cell death 6 interacting protein JBrowse link NW_004955421 1,034,843 1,109,637 RGD:9068941
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link NW_004955411 5,988,100 6,434,369 RGD:9068941
G Vps4b vacuolar protein sorting 4 homolog B JBrowse link NW_004955402 47,154,350 47,183,979 RGD:9068941
G Xpo1 exportin 1 JBrowse link NW_004955424 22,370,006 22,420,568 RGD:9068941
G Xrcc3 X-ray repair cross complementing 3 JBrowse link NW_004955538 2,499,297 2,511,898 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14546
    cellular process 13383
      cell cycle process 1306
        centrosome duplication 64
          centriole replication + 37
          negative regulation of centrosome duplication + 11
          positive regulation of centrosome duplication + 8
          regulation of centrosome duplication + 39
Path 2
Term Annotations click to browse term
  biological_process 14546
    cellular component organization or biogenesis 6058
      cellular component organization 5876
        organelle organization 3654
          cytoskeleton organization 1274
            microtubule cytoskeleton organization 539
              microtubule organizing center organization 131
                centrosome cycle 122
                  centrosome duplication 64
                    centriole replication + 37
                    negative regulation of centrosome duplication + 11
                    positive regulation of centrosome duplication + 8
                    regulation of centrosome duplication + 39
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.