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ONTOLOGY REPORT - ANNOTATIONS


Term:centrosome duplication
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Accession:GO:0051298 term browser browse the term
Definition:The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Synonyms:exact_synonym: centrosome replication


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centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRCA2 BRCA2 DNA repair associated JBrowse link 25 7,734,450 7,797,851 RGD:13508589
G BRSK1 BR serine/threonine kinase 1 JBrowse link 1 102,367,050 102,384,942 RGD:13508589
G CEP192 centrosomal protein 192 JBrowse link 7 78,401,273 78,541,918 RGD:13508589
G CHORDC1 cysteine and histidine rich domain containing 1 JBrowse link 21 10,129,812 10,152,416 RGD:13508589
G CKAP5 cytoskeleton associated protein 5 JBrowse link 18 42,673,432 42,780,320 RGD:13508589
G NDE1 nudE neurodevelopment protein 1 JBrowse link 6 28,143,244 28,186,069 RGD:13508589
G SAC3D1 SAC3 domain containing 1 JBrowse link 18 52,148,661 52,151,920 RGD:13508589
G SEH1L SEH1 like nucleoporin JBrowse link 7 78,352,153 78,383,546 RGD:13508589
G STIL STIL centriolar assembly protein JBrowse link 15 13,369,292 13,431,677 RGD:13508589
G USP33 ubiquitin specific peptidase 33 JBrowse link 6 69,118,953 69,170,864 RGD:13508589
centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2CD3 C2 domain containing 3 centriole elongation regulator JBrowse link 21 24,127,390 24,272,473 RGD:13508589
G CENPJ centromere protein J JBrowse link 25 18,555,182 18,611,133 RGD:13508589
centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCP110 centriolar coiled-coil protein 110 JBrowse link 6 25,713,100 25,738,854 RGD:13508589
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 JBrowse link 11 73,548,003 73,693,044 RGD:13508589
G CEP135 centrosomal protein 135 JBrowse link 13 48,202,649 48,280,995 RGD:13508589
G CEP152 centrosomal protein 152 JBrowse link 30 14,958,537 15,047,431 RGD:13508589
G CEP63 centrosomal protein 63 JBrowse link 23 31,249,517 31,303,145 RGD:13508589
G CEP72 centrosomal protein 72 JBrowse link 34 11,639,794 11,684,041 RGD:13508589
G CETN1 centrin 1 JBrowse link 7 67,431,020 67,431,774 RGD:13508589
G CETN2 centrin 2 JBrowse link X 120,714,676 120,720,012 RGD:13508589
G CNTROB centrobin, centriole duplication and spindle assembly protein JBrowse link 5 32,777,242 32,811,747 RGD:13508589
G DEUP1 deuterosome assembly protein 1 JBrowse link 21 7,209,524 7,334,200 RGD:13508589
G KIAA0753 KIAA0753 JBrowse link 5 30,708,361 30,749,773 RGD:13508589
G LOC483842 centrin-4 JBrowse link 19 17,550,602 17,554,984 RGD:13508589
G PLK4 polo like kinase 4 JBrowse link 19 13,041,739 13,060,300 RGD:13508589
G RTTN rotatin JBrowse link 1 8,180,831 8,326,947 RGD:13508589
G SASS6 SAS-6 centriolar assembly protein JBrowse link 6 49,859,597 49,902,407 RGD:13508589
G TSGA10 testis specific 10 JBrowse link 10 43,556,248 43,685,221 RGD:13508589
G WDR62 WD repeat domain 62 JBrowse link 1 116,594,243 116,641,206 RGD:13508589
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHMP2A charged multivesicular body protein 2A JBrowse link 1 99,405,322 99,408,257 RGD:13508589
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 JBrowse link 11 73,548,003 73,693,044 RGD:13508589
G KAT2A lysine acetyltransferase 2A JBrowse link 9 20,778,434 20,787,057 RGD:13508589
G KAT2B lysine acetyltransferase 2B JBrowse link 23 23,166,722 23,242,447 RGD:13508589
G LOC610648 RNA-binding protein 14 JBrowse link 18 50,683,227 50,728,512 RGD:13508589
G MDM1 Mdm1 nuclear protein JBrowse link 10 10,523,656 10,552,824 RGD:13508589
G TRIM37 tripartite motif containing 37 JBrowse link 9 33,446,903 33,687,650 RGD:13508589
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCNF cyclin F JBrowse link 6 38,572,883 38,592,465 RGD:13508589
G TMEM67 transmembrane protein 67 JBrowse link 29 38,655,531 38,715,774 RGD:13508589
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPJ centromere protein J JBrowse link 25 18,555,182 18,611,133 RGD:13508589
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 1 13,638,965 13,673,295 RGD:13508589
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PLK4 polo like kinase 4 JBrowse link 19 13,041,739 13,060,300 RGD:13508589
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G POC1A POC1 centriolar protein A JBrowse link 20 37,592,080 37,659,783 RGD:13508589
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 17 7,931,786 8,012,484 RGD:13508589
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALMS1 ALMS1 centrosome and basal body associated protein JBrowse link 17 49,301,397 49,513,729 RGD:13508589
G CEP295NL CEP295 N-terminal like JBrowse link 9 2,501,410 2,510,297 RGD:13508589
G CEP76 centrosomal protein 76 JBrowse link 7 78,062,793 78,092,478 RGD:13508589
G SPICE1 spindle and centriole associated protein 1 JBrowse link 33 17,765,216 17,822,413 RGD:13508589
regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP131 centrosomal protein 131 JBrowse link 9 866,384 883,141 RGD:13508589
G CHMP1A charged multivesicular body protein 1A JBrowse link 5 63,897,544 63,906,515 RGD:13508589
G CHMP2B charged multivesicular body protein 2B JBrowse link 31 789,586 817,925 RGD:13508589
G CHMP4B charged multivesicular body protein 4B JBrowse link 24 22,995,677 23,050,084 RGD:13508589
G CHMP4C charged multivesicular body protein 4C JBrowse link 29 28,839,459 28,865,793 RGD:13508589
G CHMP5 charged multivesicular body protein 5 JBrowse link 11 50,363,488 50,376,081 RGD:13508589
G FBXW5 F-box and WD repeat domain containing 5 JBrowse link 9 48,674,299 48,678,846 RGD:13508589
G GEN1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 17 13,201,540 13,233,028 RGD:13508589
G NPM1 nucleophosmin 1 JBrowse link 4 40,756,464 40,770,174 RGD:13508589
G PDCD6IP programmed cell death 6 interacting protein JBrowse link 23 4,112,299 4,199,230 RGD:13508589
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 12 19,280,866 19,744,669 RGD:13508589
G XPO1 exportin 1 JBrowse link 10 61,541,647 61,588,397 RGD:13508589
G XRCC3 X-ray repair cross complementing 3 JBrowse link 8 71,441,732 71,452,922 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13312
    cellular process 11726
      cell cycle process 809
        centrosome duplication 57
          centriole replication + 30
          negative regulation of centrosome duplication + 9
          positive regulation of centrosome duplication + 5
          regulation of centrosome duplication + 31
Path 2
Term Annotations click to browse term
  biological_process 13312
    cellular component organization or biogenesis 4239
      cellular component organization 4096
        organelle organization 2653
          cytoskeleton organization 992
            microtubule cytoskeleton organization 441
              microtubule organizing center organization 103
                centrosome cycle 98
                  centrosome duplication 57
                    centriole replication + 30
                    negative regulation of centrosome duplication + 9
                    positive regulation of centrosome duplication + 5
                    regulation of centrosome duplication + 31
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.