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ONTOLOGY REPORT - ANNOTATIONS


Term:centrosome duplication
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Accession:GO:0051298 term browser browse the term
Definition:The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Synonyms:exact_synonym: centrosome replication


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centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 JBrowse link 8 14,906,412 15,001,085 RGD:2290270
G Brca1 breast cancer 1, early onset JBrowse link 11 101,488,761 101,551,955 RGD:2290270
G Brca2 breast cancer 2, early onset JBrowse link 5 150,522,297 150,570,147 RGD:2290270
G Brsk1 BR serine/threonine kinase 1 JBrowse link 7 4,690,636 4,715,999 RGD:2290270
G Ccp110 centriolar coiled coil protein 110 JBrowse link 7 118,712,515 118,737,024 RGD:2290270
G Cenpj centromere protein J JBrowse link 14 56,526,761 56,575,489 RGD:2290270
G Cep152 centrosomal protein 152 JBrowse link 2 125,549,864 125,625,174 RGD:2290270
G Cep63 centrosomal protein 63 JBrowse link 9 102,586,578 102,626,564 RGD:2290270
G Ckap5 cytoskeleton associated protein 5 JBrowse link 2 91,526,747 91,620,679 RGD:2290270
G Nde1 nudE neurodevelopment protein 1 JBrowse link 16 14,163,275 14,192,928 RGD:2290270
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 12 16,894,978 16,988,274 RGD:2290270
G Sac3d1 SAC3 domain containing 1 JBrowse link 19 6,116,004 6,118,586 RGD:2290270
G Sass6 SAS-6 centriolar assembly protein JBrowse link 3 116,594,938 116,630,986 RGD:2290270
G Stil Scl/Tal1 interrupting locus JBrowse link 4 115,000,108 115,043,203 RGD:2290270
G Usp33 ubiquitin specific peptidase 33 JBrowse link 3 152,346,184 152,393,617 RGD:2290270
centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2cd3 C2 calcium-dependent domain containing 3 JBrowse link 7 100,372,229 100,470,159 RGD:2290270
G Cenpj centromere protein J JBrowse link 14 56,526,761 56,575,489 RGD:2290270
centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G 4933427D14Rik RIKEN cDNA 4933427D14 gene JBrowse link 11 72,153,929 72,207,482 RGD:2290270
G Ccp110 centriolar coiled coil protein 110 JBrowse link 7 118,712,515 118,737,024 RGD:2290270
G Cdk2 cyclin-dependent kinase 2 JBrowse link 10 128,697,938 128,705,051 RGD:2290270
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 4 70,216,855 70,410,435 RGD:2290270
G Cenpj centromere protein J JBrowse link 14 56,526,761 56,575,489 RGD:2290270
G Cep135 centrosomal protein 135 JBrowse link 5 76,588,653 76,646,466 RGD:2290270
G Cep152 centrosomal protein 152 JBrowse link 2 125,549,864 125,625,174 RGD:2290270
G Cep63 centrosomal protein 63 JBrowse link 9 102,586,578 102,626,564 RGD:2290270
G Cep72 centrosomal protein 72 JBrowse link 13 74,036,495 74,062,319 RGD:2290270
G Cetn1 centrin 1 JBrowse link 18 9,618,419 9,619,469 RGD:2290270
G Cetn2 centrin 2 JBrowse link X 72,913,565 72,918,344 RGD:2290270
G Cetn4 centrin 4 JBrowse link 3 37,308,627 37,312,446 RGD:2290270
G Cntrob centrobin, centrosomal BRCA2 interacting protein JBrowse link 11 69,297,909 69,323,898 RGD:2290270
G Deup1 deuterosome assembly protein 1 JBrowse link 9 15,559,864 15,628,351 RGD:2290270
G Ofd1 OFD1, centriole and centriolar satellite protein JBrowse link X 166,386,573 166,440,704 RGD:2290270
G Plk4 polo like kinase 4 JBrowse link 3 40,799,951 40,816,883 RGD:2290270
G Rttn rotatin JBrowse link 18 88,971,736 89,131,014 RGD:2290270
G Sass6 SAS-6 centriolar assembly protein JBrowse link 3 116,594,938 116,630,986 RGD:2290270
G Wdr62 WD repeat domain 62 JBrowse link 7 30,240,138 30,281,908 RGD:2290270
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chmp2a charged multivesicular body protein 2A JBrowse link 7 13,032,006 13,034,777 RGD:2290270
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 4 70,216,855 70,410,435 RGD:2290270
G Kat2a K(lysine) acetyltransferase 2A JBrowse link 11 100,704,746 100,712,485 RGD:2290270
G Kat2b K(lysine) acetyltransferase 2B JBrowse link 17 53,566,774 53,672,721 RGD:2290270
G Mdm1 transformed mouse 3T3 cell double minute 1 JBrowse link 10 118,141,540 118,168,999 RGD:2290270
G Rbm14 RNA binding motif protein 14 JBrowse link 19 4,800,566 4,811,634 RGD:2290270
G Trim37 tripartite motif-containing 37 JBrowse link 11 87,126,790 87,250,874 RGD:2290270
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnf cyclin F JBrowse link 17 24,223,230 24,251,409 RGD:2290270
G Kifc1 kinesin family member C1 JBrowse link 17 33,875,664 33,890,633 RGD:2290270
G Npm1 nucleophosmin 1 JBrowse link 11 33,152,498 33,164,142 RGD:2290270
G Nubp1 nucleotide binding protein 1 JBrowse link 16 10,411,884 10,424,453 RGD:2290270
G Tmem67 transmembrane protein 67 JBrowse link 4 12,039,355 12,090,020 RGD:2290270
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cenpj centromere protein J JBrowse link 14 56,526,761 56,575,489 RGD:2290270
G Cep120 centrosomal protein 120 JBrowse link 18 53,681,723 53,745,636 RGD:2290270
G Cep295 centrosomal protein 295 JBrowse link 9 15,316,914 15,357,849 RGD:2290270
G Vps4b vacuolar protein sorting 4B JBrowse link 1 106,770,788 106,796,725 RGD:2290270
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nup62 nucleoporin 62 JBrowse link 7 44,816,088 44,831,836 RGD:2290270
G Plk4 polo like kinase 4 JBrowse link 3 40,799,951 40,816,883 RGD:2290270
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep120 centrosomal protein 120 JBrowse link 18 53,681,723 53,745,636 RGD:2290270
G Cep295 centrosomal protein 295 JBrowse link 9 15,316,914 15,357,849 RGD:2290270
G Npm1 nucleophosmin 1 JBrowse link 11 33,152,498 33,164,142 RGD:2290270
G Poc1a POC1 centriolar protein A JBrowse link 9 106,279,443 106,350,522 RGD:2290270
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 12 16,894,978 16,988,274 RGD:2290270
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alms1 ALMS1, centrosome and basal body associated JBrowse link 6 85,587,498 85,726,611 RGD:2290270
G Cenpj centromere protein J JBrowse link 14 56,526,761 56,575,489 RGD:2290270
G Cep192 centrosomal protein 192 JBrowse link 18 67,800,054 67,885,170 RGD:2290270
G Cep295 centrosomal protein 295 JBrowse link 9 15,316,914 15,357,849 RGD:2290270
G Cep295nl CEP295 N-terminal like JBrowse link 11 118,332,360 118,342,542 RGD:2290270
G Cep76 centrosomal protein 76 JBrowse link 18 67,616,964 67,641,355 RGD:2290270
G D7Ertd443e DNA segment, Chr 7, ERATO Doi 443, expressed JBrowse link 7 134,265,780 134,520,159 RGD:2290270
G Npm1 nucleophosmin 1 JBrowse link 11 33,152,498 33,164,142 RGD:2290270
G Plk2 polo like kinase 2 JBrowse link 13 110,395,044 110,400,844 RGD:2290270
G Spice1 spindle and centriole associated protein 1 JBrowse link 16 44,347,399 44,388,492 RGD:2290270
G Stil Scl/Tal1 interrupting locus JBrowse link 4 115,000,108 115,043,203 RGD:2290270
regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cep131 centrosomal protein 131 JBrowse link 11 120,064,429 120,086,865 RGD:2290270
G Chmp1a charged multivesicular body protein 1A JBrowse link 8 123,204,261 123,212,788 RGD:2290270
G Chmp1b charged multivesicular body protein 1B JBrowse link 18 67,205,359 67,207,887 RGD:2290270
G Chmp2a charged multivesicular body protein 2A JBrowse link 7 13,032,006 13,034,777 RGD:2290270
G Chmp2b charged multivesicular body protein 2B JBrowse link 16 65,539,128 65,562,762 RGD:2290270
G Chmp3 charged multivesicular body protein 3 JBrowse link 6 71,543,831 71,582,609 RGD:2290270
G Chmp4b charged multivesicular body protein 4B JBrowse link 2 154,657,026 154,694,783 RGD:2290270
G Chmp4c charged multivesicular body protein 4C JBrowse link 3 10,366,973 10,391,005 RGD:2290270
G Chmp5 charged multivesicular body protein 5 JBrowse link 4 40,948,553 40,965,302 RGD:2290270
G Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 JBrowse link 9 18,292,267 18,314,000 RGD:2290270
G Fbxw5 F-box and WD-40 domain protein 5 JBrowse link 2 25,500,750 25,505,470 RGD:2290270
G Gen1 GEN1, Holliday junction 5' flap endonuclease JBrowse link 12 11,238,928 11,266,029 RGD:2290270
G Npm1 nucleophosmin 1 JBrowse link 11 33,152,498 33,164,142 RGD:2290270
G Pdcd6ip programmed cell death 6 interacting protein JBrowse link 9 113,651,744 113,708,279 RGD:2290270
G Pkhd1 polycystic kidney and hepatic disease 1 JBrowse link 1 20,057,779 20,618,082 RGD:2290270
G Vps4b vacuolar protein sorting 4B JBrowse link 1 106,770,788 106,796,725 RGD:2290270
G Xpo1 exportin 1 JBrowse link 11 23,255,909 23,297,597 RGD:2290270
G Xrcc3 X-ray repair complementing defective repair in Chinese hamster cells 3 JBrowse link 12 111,803,192 111,813,893 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23017
    cellular process 15767
      cell cycle process 1115
        centrosome duplication 68
          centriole replication + 39
          negative regulation of centrosome duplication + 12
          positive regulation of centrosome duplication + 9
          regulation of centrosome duplication + 43
Path 2
Term Annotations click to browse term
  biological_process 23017
    cellular component organization or biogenesis 6221
      cellular component organization 6039
        organelle organization 3582
          cytoskeleton organization 1315
            microtubule cytoskeleton organization 568
              microtubule organizing center organization 132
                centrosome cycle 123
                  centrosome duplication 68
                    centriole replication + 39
                    negative regulation of centrosome duplication + 12
                    positive regulation of centrosome duplication + 9
                    regulation of centrosome duplication + 43
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.