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ONTOLOGY REPORT - ANNOTATIONS


Term:centrosome duplication
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Accession:GO:0051298 term browser browse the term
Definition:The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Synonyms:exact_synonym: centrosome replication


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centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BRSK1 BR serine/threonine kinase 1 JBrowse link 6 59,468,289 59,499,062 RGD:14298760
G CEP192 centrosomal protein 192 JBrowse link 6 96,611,560 96,733,800 RGD:14298760
G CKAP5 cytoskeleton associated protein 5 JBrowse link 2 15,680,723 15,790,580 RGD:14298760
G NDE1 nudE neurodevelopment protein 1 JBrowse link 3 7,145,094 7,174,691 RGD:14298760
G SAC3D1 SAC3 domain containing 1 JBrowse link 2 7,138,409 7,142,294 RGD:14298760
G STIL STIL centriolar assembly protein JBrowse link 6 164,197,511 164,266,615 RGD:14298760
G USP33 ubiquitin specific peptidase 33 JBrowse link 6 135,524,372 135,589,742 RGD:14298760
centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C2CD3 C2 domain containing 3 centriole elongation regulator JBrowse link 9 8,393,610 8,512,843 RGD:14298760
G CENPJ centromere protein J JBrowse link 11 289,660 357,920 RGD:14298760
centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCP110 centriolar coiled-coil protein 110 JBrowse link 3 26,160,195 26,188,092 RGD:14298760
G CDK2 cyclin dependent kinase 2 JBrowse link 5 21,365,723 21,372,170 RGD:14298760
G CEP135 centrosomal protein 135 JBrowse link 8 55,250,902 55,323,396 RGD:14298760
G CEP152 centrosomal protein 152 JBrowse link 1 122,876,146 122,979,851 RGD:14298760
G CEP63 centrosomal protein 63 JBrowse link 13 75,605,622 75,707,087 RGD:14298760
G CEP72 centrosomal protein 72 JBrowse link 16 79,559,046 79,591,262 RGD:14298760
G CETN1 centrin 1 JBrowse link 6 105,740,188 105,742,226 RGD:14298760
G CETN2 centrin 2 JBrowse link X 123,902,240 123,906,046 RGD:14298760
G CNTROB centrobin, centriole duplication and spindle assembly protein JBrowse link 12 53,181,096 53,201,670 RGD:14298760
G DEUP1 deuterosome assembly protein 1 JBrowse link 9 25,688,394 25,893,105 RGD:14298760
G KIAA0753 KIAA0753 ortholog JBrowse link 12 50,737,158 50,793,187 RGD:14298760
G LOC100622849 centrin-4 JBrowse link 8 101,430,196 101,433,752 RGD:14298760
G PITPNM3 PITPNM family member 3 JBrowse link 12 50,806,302 50,898,316 RGD:14298760
G PLK4 polo like kinase 4 JBrowse link 8 96,989,011 97,013,324 RGD:14298760
G RTTN rotatin JBrowse link 1 152,688,305 152,833,969 RGD:14298760
G SASS6 SAS-6 centriolar assembly protein JBrowse link 4 117,985,599 118,049,129 RGD:14298760
G WDR62 WD repeat domain 62 JBrowse link 6 45,418,966 45,477,619 RGD:14298760
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHMP2A charged multivesicular body protein 2A JBrowse link 6 63,102,155 63,105,032 RGD:14298760
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G KAT2A lysine acetyltransferase 2A JBrowse link 12 20,638,493 20,647,464 RGD:14298760
G KAT2B lysine acetyltransferase 2B JBrowse link 13 6,985,151 7,099,771 RGD:14298760
G MDM1 Mdm1 nuclear protein JBrowse link 5 32,640,939 32,673,624 RGD:14298760
G RBM14 RNA binding motif protein 14 JBrowse link 2 5,791,445 5,800,784 RGD:14298760
G TRIM37 tripartite motif containing 37 JBrowse link 12 35,259,292 35,393,464 RGD:14298760
negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCNF cyclin F JBrowse link 3 39,585,597 39,603,088 RGD:14298760
G NPM1 nucleophosmin 1 JBrowse link 16 52,767,263 52,781,862 RGD:14298760
G TMEM67 transmembrane protein 67 JBrowse link 4 42,878,249 42,931,106 RGD:14298760
positive regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CENPJ centromere protein J JBrowse link 11 289,660 357,920 RGD:14298760
G CEP120 centrosomal protein 120 JBrowse link 2 126,840,262 126,930,117 RGD:14298760
G CEP295 centrosomal protein 295 JBrowse link 9 26,103,267 26,155,067 RGD:14298760
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 1 158,233,039 158,273,533 RGD:14298760
positive regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NUP62 nucleoporin 62 JBrowse link 6 54,921,627 54,945,705 RGD:14298760
G PLK4 polo like kinase 4 JBrowse link 8 96,989,011 97,013,324 RGD:14298760
positive regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G POC1A POC1 centriolar protein A JBrowse link 13 34,227,884 34,308,099 RGD:14298760
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 3 125,353,063 125,493,368 RGD:14298760
regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALMS1 ALMS1 centrosome and basal body associated protein JBrowse link 3 69,253,742 69,417,043 RGD:14298760
G C14H10orf90 chromosome 14 C10orf90 homolog JBrowse link 14 135,718,618 135,954,019 RGD:14298760
G CENPJ centromere protein J JBrowse link 11 289,660 357,920 RGD:14298760
G CEP295 centrosomal protein 295 JBrowse link 9 26,103,267 26,155,067 RGD:14298760
G CEP76 centrosomal protein 76 JBrowse link 6 96,893,529 96,913,226 RGD:14298760
G NPM1 nucleophosmin 1 JBrowse link 16 52,767,263 52,781,862 RGD:14298760
G PLK2 polo like kinase 2 JBrowse link 16 37,299,116 37,305,114 RGD:14298760
G SPICE1 spindle and centriole associated protein 1 JBrowse link 13 146,411,280 146,469,695 RGD:14298760
G STIL STIL centriolar assembly protein JBrowse link 6 164,197,511 164,266,615 RGD:14298760
regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEP131 centrosomal protein 131 JBrowse link 12 1,537,900 1,556,931 RGD:14298760
G CHMP1A charged multivesicular body protein 1A JBrowse link 6 351,878 358,655 RGD:14298760
G CHMP2B charged multivesicular body protein 2B JBrowse link 13 168,534,950 168,569,574 RGD:14298760
G CHMP4B charged multivesicular body protein 4B JBrowse link 17 37,285,422 37,334,103 RGD:14298760
G CHMP4C charged multivesicular body protein 4C JBrowse link 4 54,860,481 54,895,229 RGD:14298760
G CHMP5 charged multivesicular body protein 5 JBrowse link 10 33,212,769 33,227,237 RGD:14298760
G FBXW5 F-box and WD repeat domain containing 5 RGD:14298760
G GEN1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 3 120,067,792 120,097,305 RGD:14298760
G NPM1 nucleophosmin 1 JBrowse link 16 52,767,263 52,781,862 RGD:14298760
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin JBrowse link 7 45,447,354 45,925,141 RGD:14298760
G XPO1 exportin 1 JBrowse link 3 80,255,016 80,300,260 RGD:14298760
G XRCC3 X-ray repair cross complementing 3 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14320
    cellular process 12707
      cell cycle process 863
        centrosome duplication 57
          centriole replication + 36
          negative regulation of centrosome duplication + 9
          positive regulation of centrosome duplication + 8
          regulation of centrosome duplication + 34
Path 2
Term Annotations click to browse term
  biological_process 14320
    cellular component organization or biogenesis 4538
      cellular component organization 4388
        organelle organization 2803
          cytoskeleton organization 1041
            microtubule cytoskeleton organization 464
              microtubule organizing center organization 108
                centrosome cycle 101
                  centrosome duplication 57
                    centriole replication + 36
                    negative regulation of centrosome duplication + 9
                    positive regulation of centrosome duplication + 8
                    regulation of centrosome duplication + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.