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ONTOLOGY REPORT - ANNOTATIONS


Term:chromosome separation
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Accession:GO:0051304 term browser browse the term
Definition:The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
Synonyms:narrow_synonym: rDNA separation
 related_synonym: chromatid release
 alt_id: GO:0034500


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chromosome separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncapd2 non-SMC condensin I complex, subunit D2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:157,682,855...157,705,903
Ensembl chr 4:157,683,077...157,704,596
JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:28,075,629...28,145,024
Ensembl chr 8:28,075,551...28,144,741
JBrowse link
G Recql5 RecQ like helicase 5 ISO
ISS
(PMID:22013166)
GO_REF:0000024
RGD
UniProt
PMID:22013166 GO_REF:0000024 NCBI chr10:104,443,735...104,482,889
Ensembl chr10:104,443,736...104,482,838
JBrowse link
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` ISO
ISS
(PMID:21549307)
GO_REF:0000024
RGD
UniProt
PMID:21549307 GO_REF:0000024 NCBI chr 4:95,884,020...95,945,248
Ensembl chr 4:95,884,743...95,945,248
JBrowse link
G Top3a DNA topoisomerase III alpha ISO (PMID:30057030) RGD PMID:30057030 NCBI chr10:46,980,646...47,018,728
Ensembl chr10:46,981,958...47,018,537
JBrowse link
G Ttk Ttk protein kinase IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 ISO (PMID:22581055) RGD PMID:22581055 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
female meiosis chromosome separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncaph non-SMC condensin I complex, subunit H ISO MGI:MGI:1289164 (MGI:MGI:5784807|PMID:25961503) RGD PMID:25961503 MGI:MGI:5784807 NCBI chr 3:119,583,798...119,611,148
Ensembl chr 3:119,583,648...119,611,136
JBrowse link
G Ncaph2 non-SMC condensin II complex, subunit H2 IEA
ISO
GO_REF:0000107
(MGI:MGI:5784807|PMID:25961503)
Ensembl
RGD
PMID:25961503 GO_REF:0000107, MGI:MGI:5784807 NCBI chr 7:130,326,597...130,343,655
Ensembl chr 7:130,326,600...130,342,493
JBrowse link
male meiosis chromosome separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G M1ap meiosis 1 associated protein ISO
IBA
(MGI:MGI:5473951|PMID:23269666)
PMID:21873635
RGD PMID:23269666, PMID:21873635 MGI:MGI:5473951, RGD:13792537 NCBI chr 4:113,772,716...113,864,171
Ensembl chr 4:113,782,206...113,863,224
JBrowse link
meiotic chromosome separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Espl1 extra spindle pole bodies like 1, separase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:143,896,890...143,923,868
Ensembl chr 7:143,897,014...143,923,868
JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 ISO (MGI:MGI:5317363|PMID:21795393) RGD PMID:21795393 MGI:MGI:5317363 NCBI chr 8:28,075,629...28,145,024
Ensembl chr 8:28,075,551...28,144,741
JBrowse link
meiotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttk Ttk protein kinase ISO
IBA
MGI:MGI:5056148 (MGI:MGI:5049806|PMID:21558374)
PMID:21873635
RGD PMID:21558374, PMID:21873635 MGI:MGI:5049806, RGD:13792537 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
metaphase/anaphase transition of mitotic cell cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc1 anaphase promoting complex subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:121,147,484...121,226,125
Ensembl chr 3:121,147,547...121,226,125
JBrowse link
G Anapc7 anaphase promoting complex subunit 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:39,613,898...39,641,999
Ensembl chr12:39,614,733...39,641,285
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO MGI:MGI:1333889|MGI:MGI:1856318|MGI:MGI:3589207 (MGI:MGI:3574170|PMID:15767571), (MGI:MGI:3588595|PMID:16025118) RGD PMID:15767571, PMID:16025118 MGI:MGI:3574170, MGI:MGI:3588595 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B ISO MGI:MGI:88039 (MGI:MGI:3574170|PMID:15767571) RGD PMID:15767571 MGI:MGI:3574170 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Cdc16 cell division cycle 16 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:81,493,355...81,516,493
Ensembl chr16:81,493,355...81,516,493
JBrowse link
G Cdc23 cell division cycle 23 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:27,430,924...27,452,569
Ensembl chr18:27,430,905...27,452,420
JBrowse link
G Cdc27 cell division cycle 27 ISO
IBA
(PMID:7736578)
PMID:21873635
RGD PMID:7736578, PMID:21873635 RGD:13792537 NCBI chr10:92,551,754...92,602,214
Ensembl chr10:92,554,081...92,602,082
JBrowse link
G Cit citron rho-interacting serine/threonine kinase ISO MGI:MGI:2447844 (MGI:MGI:3606716|PMID:12764032) RGD PMID:12764032 MGI:MGI:3606716 NCBI chr12:46,334,669...46,494,152
Ensembl chr12:46,334,665...46,494,174
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 ISO (PMID:23532825) RGD PMID:23532825 NCBI chr14:82,336,283...82,350,069
Ensembl chr14:82,336,324...82,347,679
JBrowse link
mitotic sister chromatid separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 ISO (PMID:22306653) RGD PMID:22306653 NCBI chr 9:93,767,837...94,161,106
Ensembl chr 9:93,660,680...94,160,760
JBrowse link
G Ncaph2 non-SMC condensin II complex, subunit H2 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:MGI:5805571|PMID:27737961)
Ensembl
RGD
PMID:27737961, PMID:21873635 GO_REF:0000107, MGI:MGI:5805571, RGD:13792537 NCBI chr 7:130,326,597...130,343,655
Ensembl chr 7:130,326,600...130,342,493
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha ISO MGI:MGI:5287252 (MGI:MGI:5586612|PMID:24899574) RGD PMID:24899574 MGI:MGI:5586612 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(MGI:MGI:5318128|PMID:22405274)
Ensembl
UniProt
RGD
PMID:22405274, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5318128, RGD:13792537 NCBI chr10:74,724,070...74,849,172
Ensembl chr10:74,724,549...74,849,194
JBrowse link
mitotic spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO
IEA
(PMID:17227893)
GO_REF:0000107
RGD
Ensembl
PMID:17227893 GO_REF:0000107 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Atm ATM serine/threonine kinase ISO (PMID:11943150) RGD PMID:11943150 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Aurkb aurora kinase B IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISS
ISO
GO_REF:0000024
(PMID:12805209)
UniProt
RGD
PMID:12805209 GO_REF:0000024 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
JBrowse link
G Cenpe centromere protein E ISO (MGI:MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:MGI:2673075 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Ik IK cytokine ISO
ISS
(PMID:22351768)
GO_REF:0000024
RGD
UniProt
PMID:22351768 GO_REF:0000024 NCBI chr18:29,587,901...29,602,705
Ensembl chr18:29,587,901...29,608,338
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member ISO MGI:MGI:3844604 (MGI:MGI:3844372|PMID:19376971) RGD PMID:19376971 MGI:MGI:3844372 NCBI chr 8:79,781,941...79,783,845
Ensembl chr 8:79,781,983...79,783,592
JBrowse link
G Klhl22 kelch-like family member 22 ISO
IBA
ISS
(PMID:23455478)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23455478, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:87,646,489...87,718,808
Ensembl chr11:87,677,966...87,718,826
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 ISO
IBA
(PMID:18981471)
PMID:21873635
RGD PMID:18981471, PMID:21873635 RGD:13792537 NCBI chr12:16,410,083...16,721,232
Ensembl chr12:16,410,083...16,719,824
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO
IBA
MGI:MGI:2178781 (MGI:MGI:1930685|PMID:11201745)
PMID:21873635
(PMID:18981471)
RGD PMID:11201745, PMID:18981471, PMID:21873635 MGI:MGI:1930685, RGD:13792537 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Plk1 polo-like kinase 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:23455478)
Ensembl
UniProt
RGD
PMID:23455478 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Psmg2 proteasome assembly chaperone 2 ISO (MGI:MGI:2388532|PMID:12147697) RGD PMID:12147697 MGI:MGI:2388532 NCBI chr18:63,394,991...63,420,491
Ensembl chr18:63,394,900...63,409,600
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:19,628,070...19,652,914
Ensembl chr10:19,628,258...19,652,898
JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(MGI:MGI:5318128|PMID:22405274)
Ensembl
UniProt
RGD
PMID:22405274, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5318128, RGD:13792537 NCBI chr10:74,724,070...74,849,172
Ensembl chr10:74,724,549...74,849,194
JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISS
ISO
GO_REF:0000024
(PMID:20133940)
UniProt
RGD
PMID:20133940 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 ISO
ISS
(PMID:28553959)
GO_REF:0000024
RGD
UniProt
PMID:28553959 GO_REF:0000024 NCBI chr 1:31,967,980...32,012,923
Ensembl chr 1:31,967,978...32,012,919
JBrowse link
G Ttk Ttk protein kinase ISO
IBA
MGI:MGI:5056148 (MGI:MGI:5608719|PMID:25197064)
PMID:21873635
RGD PMID:25197064, PMID:21873635 MGI:MGI:5608719, RGD:13792537 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Zfp207 zinc finger protein 207 ISO
IBA
(PMID:24462186), (PMID:24462187)
PMID:21873635
RGD PMID:24462186, PMID:24462187, PMID:21873635 RGD:13792537 NCBI chr10:67,762,970...67,784,854
Ensembl chr10:67,762,995...67,774,787
JBrowse link
G Zw10 zw10 kinetochore protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:53,365,881...53,390,742
Ensembl chr 8:53,365,857...53,390,930
JBrowse link
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mos MOS proto-oncogene, serine/threonine kinase ISS
ISO
IEA
IBA
GO_REF:0000024
(MGI:MGI:67285|PMID:8015610), (MGI:MGI:67286|PMID:8015609)
GO_REF:0000107
(PMID:12533425)
PMID:21873635
UniProt
RGD
Ensembl
PMID:8015609, PMID:8015610, PMID:12533425, PMID:21873635 GO_REF:0000024, GO_REF:0000107, MGI:MGI:67285, MGI:MGI:67286, RGD:13792537 NCBI chr 5:16,746,085...16,747,392
Ensembl chr 5:16,746,197...16,747,222
JBrowse link
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo5 F-box protein 5 ISO (PMID:11988738), (PMID:16921029) RGD PMID:11988738, PMID:16921029 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Rad21 RAD21 cohesin complex component ISO (MGI:MGI:1340883|PMID:10375619) RGD PMID:10375619 MGI:MGI:1340883 NCBI chr 7:91,511,755...91,538,673
Ensembl chr 7:91,511,756...91,538,673
JBrowse link
negative regulation of mitotic sister chromatid separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pttg1 PTTG1 regulator of sister chromatid separation, securin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
positive regulation of chromosome separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Numa1 nuclear mitotic apparatus protein 1 ISO (PMID:23921553) RGD PMID:23921553 NCBI chr 1:167,044,544...167,091,453
Ensembl chr 1:167,051,209...167,091,453
JBrowse link
G Plscr1 phospholipid scramblase 1 ISO
ISS
(PMID:27206388)
GO_REF:0000024
RGD
UniProt
PMID:27206388 GO_REF:0000024 NCBI chr 8:99,625,523...99,645,882
Ensembl chr 8:99,625,545...99,725,217
JBrowse link
positive regulation of metaphase/anaphase transition of meiosis I term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk15 mitogen-activated protein kinase 15 IEA
ISO
GO_REF:0000107
(MGI:MGI:6154463|PMID:23351492)
Ensembl
RGD
PMID:23351492 GO_REF:0000107, MGI:MGI:6154463 NCBI chr 7:117,041,287...117,061,799
Ensembl chr 7:117,055,395...117,061,047
JBrowse link
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19229290)
Ensembl
UniProt
RGD
PMID:19229290 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:36,910,064...36,940,868
Ensembl chr 6:36,910,675...36,940,868
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO (PMID:20870947)
(MGI:MGI:4839685|PMID:20870947)
RGD PMID:20870947 MGI:MGI:4839685 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Ndc80 NDC80 kinetochore complex component ISO (PMID:25743205) RGD PMID:25743205 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Pcid2 PCI domain containing 2 ISO (PMID:20870947)
(MGI:MGI:4839685|PMID:20870947)
RGD PMID:20870947 MGI:MGI:4839685 NCBI chr16:81,757,582...81,783,047
Ensembl chr16:81,756,971...81,783,047
JBrowse link
G Tpr translocated promoter region, nuclear basket protein ISS
ISO
GO_REF:0000024
(PMID:18981471), (PMID:19273613)
UniProt
RGD
PMID:18981471, PMID:19273613 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc11 anaphase promoting complex subunit 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:109,774,779...109,785,877
Ensembl chr10:109,774,878...109,785,877
JBrowse link
G Anapc4 anaphase promoting complex subunit 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:60,471,962...60,503,803
Ensembl chr14:60,471,962...60,503,803
JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:39,209,134...39,242,696
Ensembl chr12:39,209,129...39,242,690
JBrowse link
G Anapc7 anaphase promoting complex subunit 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:39,613,898...39,641,999
Ensembl chr12:39,614,733...39,641,285
JBrowse link
G Cdc16 cell division cycle 16 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:81,493,355...81,516,493
Ensembl chr16:81,493,355...81,516,493
JBrowse link
G Cdc23 cell division cycle 23 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:27,430,924...27,452,569
Ensembl chr18:27,430,905...27,452,420
JBrowse link
G Cdc27 cell division cycle 27 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:92,551,754...92,602,214
Ensembl chr10:92,554,081...92,602,082
JBrowse link
G Cenpe centromere protein E ISO (MGI:MGI:2673075|PMID:12925705) RGD PMID:12925705 MGI:MGI:2673075 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Cul3 cullin 3 IEA
ISO
GO_REF:0000107
(PMID:17543862)
Ensembl
RGD
PMID:17543862 GO_REF:0000107 NCBI chr 9:86,044,485...86,129,066
Ensembl chr 9:86,044,485...86,129,329
JBrowse link
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase ISO
ISS
(PMID:19502785)
GO_REF:0000024
RGD
UniProt
PMID:19502785 GO_REF:0000024 NCBI chr 7:99,677,295...99,900,765
Ensembl chr 7:99,677,290...99,900,764
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO
IEA
(PMID:20551165)
GO_REF:0000107
RGD
Ensembl
PMID:20551165 GO_REF:0000107 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
regulation of chromosome separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csnk2a1 casein kinase 2 alpha 1 ISO
ISS
(PMID:11704824)
GO_REF:0000024
RGD
UniProt
PMID:11704824 GO_REF:0000024 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 ISO
IBA
(PMID:11704824)
PMID:21873635
RGD PMID:11704824, PMID:21873635 RGD:13792537 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc15 anaphase promoting complex subunit 15 ISO
IBA
ISS
(PMID:21926987)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:21926987, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:166,981,738...166,985,363
Ensembl chr 1:166,983,175...166,985,054
JBrowse link
G Ccnb1 cyclin B1 ISO (PMID:18195732) RGD PMID:18195732 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 ISS
ISO
IEA
GO_REF:0000024
(PMID:19282672)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19282672 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 ISO
IEA
(PMID:17724024)
GO_REF:0000107
RGD
Ensembl
PMID:17724024 GO_REF:0000107 NCBI chr 1:193,335,629...193,391,620
Ensembl chr 1:193,335,645...193,391,638
JBrowse link
G Usp44 ubiquitin specific peptidase 44 ISO (MGI:MGI:5448515|PMID:21853124) RGD PMID:21853124 MGI:MGI:5448515 NCBI chr 7:34,714,293...34,759,352
Ensembl chr 7:34,744,483...34,759,206
JBrowse link
regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc23 cell division cycle 23 ISO (PMID:9790767) RGD PMID:9790767 NCBI chr18:27,430,924...27,452,569
Ensembl chr18:27,430,905...27,452,420
JBrowse link
G Cdc26 cell division cycle 26 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:78,252,168...78,267,137
Ensembl chr 5:78,253,397...78,267,063
JBrowse link
G Cdc6 cell division cycle 6 ISO (PMID:21041660) RGD PMID:21041660 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cenpe centromere protein E ISO (PMID:2022189) RGD PMID:2022189 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 ISO (PMID:24163370) RGD PMID:24163370 NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246
JBrowse link
G Nek6 NIMA-related kinase 6 ISO
ISS
(PMID:14563848)
GO_REF:0000024
RGD
UniProt
PMID:14563848 GO_REF:0000024 NCBI chr 3:22,811,927...22,888,598
Ensembl chr 3:22,811,927...22,888,598
JBrowse link
G Plk1 polo-like kinase 1 ISO (PMID:21041660), (PMID:23509069) RGD PMID:21041660, PMID:23509069 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Riok2 RIO kinase 2 ISO (PMID:21880710) RGD PMID:21880710 NCBI chr 1:59,130,008...59,146,457
Ensembl chr 1:59,129,951...59,146,776
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
regulation of mitotic sister chromatid separation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpr translocated promoter region, nuclear basket protein ISO
ISS
(PMID:20133940)
GO_REF:0000024
RGD
UniProt
PMID:20133940 GO_REF:0000024 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
resolution of meiotic recombination intermediates term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07030926.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:109,891,383...109,891,879 JBrowse link
G AABR07048387.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 5:76,240,167...76,261,198 JBrowse link
G AC117889.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:975,697...1,003,352 JBrowse link
G Cenps centromere protein S ISO (PMID:20347428) RGD PMID:20347428 NCBI chr 5:165,946,106...165,955,723 JBrowse link
G Cenpx centromere protein X ISO (PMID:20347428) RGD PMID:20347428 NCBI chr10:109,890,904...109,893,804 JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,366,820...82,375,510
Ensembl chr10:82,367,084...82,374,171
JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,253,552...14,257,017
Ensembl chr10:14,254,252...14,256,930
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Fancm FA complementation group M ISO (PMID:20347428) RGD PMID:20347428 NCBI chr 6:86,823,195...86,877,067
Ensembl chr 6:86,823,684...86,876,633
JBrowse link
G Hfm1 helicase for meiosis 1 ISO
IBA
(MGI:MGI:5477835|PMID:23555294)
PMID:21873635
RGD PMID:23555294, PMID:21873635 MGI:MGI:5477835, RGD:13792537 NCBI chr14:3,879,172...3,961,139
Ensembl chr14:3,882,398...3,960,909
JBrowse link
G Meiob meiosis specific with OB-fold ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(MGI:MGI:5527015|PMID:24068956), (MGI:MGI:5538413|PMID:24240703)
UniProt
RGD
PMID:24068956, PMID:24240703, PMID:21873635 GO_REF:0000024, MGI:MGI:5527015, MGI:MGI:5538413, RGD:13792537 NCBI chr10:14,174,645...14,206,026
Ensembl chr10:14,174,732...14,206,025
JBrowse link
G Mlh1 mutL homolog 1 IEA
ISO
GO_REF:0000107
MGI:MGI:1857946 (MGI:MGI:1340178|PMID:10385520), (MGI:MGI:2386157|PMID:12217320)
Ensembl
RGD
PMID:10385520, PMID:12217320 GO_REF:0000107, MGI:MGI:1340178, MGI:MGI:2386157 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Msh4 mutS homolog 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:260,057,708...260,108,897
Ensembl chr 2:260,057,855...260,108,897
JBrowse link
G Mus81 MUS81 structure-specific endonuclease subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:220,862,474...220,867,973
Ensembl chr 1:220,862,386...220,867,815
JBrowse link
G Rmi1 RecQ mediated genome instability 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:6,658,285...6,665,618
Ensembl chr17:6,658,388...6,660,536
JBrowse link
G Shoc1 shortage in chiasmata 1 ISO (MGI:MGI:6159552|PMID:29742103) RGD PMID:29742103 MGI:MGI:6159552 NCBI chr 5:76,190,486...76,298,723 JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:11,787,756...11,808,326
Ensembl chr10:11,786,121...11,807,928
JBrowse link
G Tex11 testis expressed 11 ISO MGI:MGI:3526163 (MGI:MGI:3774244|PMID:18316482) RGD PMID:18316482 MGI:MGI:3774244 NCBI chr  X:70,670,212...70,946,621
Ensembl chr  X:70,670,322...70,946,565
JBrowse link
G Top2a DNA topoisomerase II alpha IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      chromosome segregation 334
        chromosome separation 92
          centromere separation + 0
          meiotic chromosome separation + 27
          mitotic sister chromatid separation + 59
          negative regulation of chromosome separation + 38
          positive regulation of chromosome separation + 15
          regulation of chromosome separation + 62
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell cycle 1534
        cell cycle process 1210
          chromosome separation 92
            centromere separation + 0
            meiotic chromosome separation + 27
            mitotic sister chromatid separation + 59
            negative regulation of chromosome separation + 38
            positive regulation of chromosome separation + 15
            regulation of chromosome separation + 62
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.