ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic sister chromatid separation
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Accession:GO:0051306 term browser browse the term
Definition:The process in which sister chromatids are physically detached from each other during mitosis.
Synonyms:exact_synonym: mitotic sister chromatid resolution;   sister chromatid separation during mitosis
 related_synonym: chromosome separation during mitosis;   mitotic chromosome separation


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mitotic sister chromatid separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 JBrowse link 9 93,767,837 94,161,106 RGD:1624291
RGD:1600115
G Ncaph2 non-SMC condensin II complex, subunit H2 JBrowse link 7 130,326,597 130,343,655 RGD:1600115
RGD:13792537
RGD:1624291
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha JBrowse link 1 60,717,386 60,736,629 RGD:1624291
RGD:1600115
G Tex14 testis expressed 14, intercellular bridge forming factor JBrowse link 10 74,724,070 74,849,172 RGD:1600115
RGD:13792537
RGD:1624291
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdt1 chromatin licensing and DNA replication factor 1 JBrowse link 19 55,381,565 55,386,511 RGD:1624291
RGD:1600115
metaphase/anaphase transition of mitotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anapc1 anaphase promoting complex subunit 1 JBrowse link 3 121,147,484 121,226,125 RGD:13792537
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:1624291
RGD:1600115
G Cdc27 cell division cycle 27 JBrowse link 10 92,551,754 92,602,214 RGD:1624291
RGD:1600115
G Cit citron rho-interacting serine/threonine kinase JBrowse link 12 46,334,669 46,494,152 RGD:1624291
G Tacc3 transforming, acidic coiled-coil containing protein 3 JBrowse link 14 82,336,283 82,350,069 RGD:1624291
mitotic spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
RGD:1600115
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
RGD:1600115
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1600115
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:1600115
RGD:1624291
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:13792537
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:13792537
G Bub3 BUB3 mitotic checkpoint protein JBrowse link 1 203,526,853 203,537,459 RGD:13792537
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Ik IK cytokine JBrowse link 18 29,587,901 29,602,705 RGD:1624291
RGD:1600115
G Khdc3 KH domain containing 3, subcortical maternal complex member JBrowse link 8 79,781,941 79,783,845 RGD:1624291
G Klhl22 kelch-like family member 22 JBrowse link 11 87,646,489 87,718,808 RGD:1600115
RGD:13792537
RGD:1624291
G Mad1l1 mitotic arrest deficient 1 like 1 JBrowse link 12 16,410,083 16,721,232 RGD:13792537
RGD:1624291
G Mad2l1 mitotic arrest deficient 2 like 1 JBrowse link 4 97,530,993 97,543,179 RGD:1624291
RGD:13792537
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1600115
RGD:1624291
G Psmg2 proteasome assembly chaperone 2 JBrowse link 18 63,394,991 63,420,491 RGD:1624291
RGD:1600115
G Spdl1 spindle apparatus coiled-coil protein 1 JBrowse link 10 19,628,070 19,652,914 RGD:1600115
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Tex14 testis expressed 14, intercellular bridge forming factor JBrowse link 10 74,724,070 74,849,172 RGD:1600115
RGD:13792537
RGD:1624291
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1600115
RGD:1624291
RGD:13792537
G Trip13 thyroid hormone receptor interactor 13 JBrowse link 1 31,967,980 32,012,923 RGD:1624291
RGD:1600115
G Ttk Ttk protein kinase JBrowse link 8 91,368,065 91,405,995 RGD:1624291
RGD:13792537
G Zfp207 zinc finger protein 207 JBrowse link 10 67,762,970 67,784,854 RGD:1624291
RGD:13792537
G Zw10 zw10 kinetochore protein JBrowse link 8 53,365,881 53,390,742 RGD:13792537
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxo5 F-box protein 5 JBrowse link 1 42,461,277 42,467,646 RGD:1600115
RGD:1624291
G Rad21 RAD21 cohesin complex component JBrowse link 7 91,511,755 91,538,673 RGD:1624291
RGD:1600115
negative regulation of mitotic sister chromatid separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pttg1 PTTG1 regulator of sister chromatid separation, securin JBrowse link 10 29,014,332 29,026,088 RGD:13792537
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:1600115
RGD:1624291
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 6 36,910,064 36,940,868 RGD:1624291
RGD:1600115
G Mad2l1 mitotic arrest deficient 2 like 1 JBrowse link 4 97,530,993 97,543,179 RGD:1624291
RGD:1600115
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
RGD:1600115
G Pcid2 PCI domain containing 2 JBrowse link 16 81,757,582 81,783,047 RGD:1624291
RGD:1600115
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1600115
RGD:1624291
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
RGD:1600115
positive regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anapc11 anaphase promoting complex subunit 11 JBrowse link 10 109,774,779 109,785,877 RGD:13792537
G Anapc4 anaphase promoting complex subunit 4 JBrowse link 14 60,471,962 60,503,803 RGD:13792537
G Anapc5 anaphase-promoting complex subunit 5 JBrowse link 12 39,209,134 39,242,696 RGD:13792537
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Cul3 cullin 3 JBrowse link 9 86,044,485 86,129,066 RGD:1600115
RGD:1624291
G Nsmce2 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase JBrowse link 7 99,677,295 99,900,765 RGD:1624291
RGD:1600115
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:1624291
RGD:1600115
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anapc15 anaphase promoting complex subunit 15 JBrowse link 1 166,981,738 166,985,363 RGD:1624291
RGD:13792537
RGD:1600115
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1624291
RGD:1600115
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:1600115
G Lcmt1 leucine carboxyl methyltransferase 1 JBrowse link 1 193,335,629 193,391,620 RGD:1624291
RGD:1600115
G Usp44 ubiquitin specific peptidase 44 JBrowse link 7 34,714,293 34,759,352 RGD:1624291
regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdc23 cell division cycle 23 JBrowse link 18 27,430,924 27,452,569 RGD:1624291
RGD:1600115
G Cdc26 cell division cycle 26 JBrowse link 5 78,252,168 78,267,137 RGD:1600115
G Cdc6 cell division cycle 6 JBrowse link 10 86,819,477 86,833,301 RGD:1624291
RGD:1600115
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
RGD:1600115
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 JBrowse link 9 60,451,476 60,843,160 RGD:1624291
RGD:1600115
G Nek6 NIMA-related kinase 6 JBrowse link 3 22,811,927 22,888,598 RGD:1624291
RGD:1600115
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1624291
G Riok2 RIO kinase 2 JBrowse link 1 59,130,008 59,146,457 RGD:1600115
RGD:1624291
regulation of mitotic sister chromatid separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    cellular process 16077
      cell cycle process 1129
        mitotic cell cycle process 662
          mitotic sister chromatid separation 57
            mitotic sister chromatid arm separation + 0
            negative regulation of mitotic sister chromatid separation + 38
            positive regulation of mitotic sister chromatid separation + 8
            regulation of mitotic sister chromatid separation + 54
Path 2
Term Annotations click to browse term
  biological_process 17926
    cellular process 16077
      cellular component organization 6054
        organelle organization 3647
          organelle fission 459
            nuclear division 411
              mitotic nuclear division 265
                mitotic sister chromatid segregation 149
                  mitotic sister chromatid separation 57
                    mitotic sister chromatid arm separation + 0
                    negative regulation of mitotic sister chromatid separation + 38
                    positive regulation of mitotic sister chromatid separation + 8
                    regulation of mitotic sister chromatid separation + 54
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.