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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of lyase activity
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Accession:GO:0051339 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
Synonyms:exact_synonym: lyase regulator


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negative regulation of adenylate cyclase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgrv1 adhesion G protein-coupled receptor V1 JBrowse link 2 8,926,843 9,504,455 RGD:1624291
RGD:1600115
G Akap5 A-kinase anchoring protein 5 JBrowse link 6 99,356,509 99,361,909 RGD:7242424
RGD:1624291
RGD:13800547
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:6902943
G Akap9 A-kinase anchoring protein 9 JBrowse link 4 27,195,346 27,331,582 RGD:2313147
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
RGD:13792537
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:13792537
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 JBrowse link 20 1,955,344 1,984,907 RGD:2315493
G Galr1 galanin receptor 1 JBrowse link 18 79,243,009 79,258,570 RGD:1600115
G Galr2 galanin receptor 2 JBrowse link 10 105,156,793 105,159,221 RGD:1600115
G Galr3 galanin receptor 3 JBrowse link 7 120,271,451 120,276,243 RGD:1600115
G Gpr87 G protein-coupled receptor 87 JBrowse link 2 149,398,949 149,418,041 RGD:1600115
G Hrh3 histamine receptor H3 JBrowse link 3 175,474,310 175,479,395 RGD:632981
G LOC103690156 galanin receptor type 2 JBrowse link 10 105,234,244 105,241,704 RGD:1600115
G LOC500460 similar to olfactory receptor Olr841 JBrowse link 5 64,614,755 64,615,714 RGD:13792537
G Npr3 natriuretic peptide receptor 3 JBrowse link 2 61,883,946 61,950,291 RGD:1601497
G Olr1257 olfactory receptor 1257 JBrowse link 8 42,429,993 42,430,928 RGD:13792537
G Olr1320 olfactory receptor 1320 JBrowse link 8 43,628,182 43,629,120 RGD:13792537
G Olr533 olfactory receptor 533 JBrowse link 3 74,574,075 74,575,010 RGD:13792537
G Olr841 olfactory receptor 841 JBrowse link 5 64,621,407 64,622,359 RGD:13792537
G P2ry13 purinergic receptor P2Y13 JBrowse link 2 149,429,648 149,432,864 RGD:1600115
G Palm paralemmin JBrowse link 7 12,708,024 12,721,055 RGD:1624291
RGD:13792537
negative regulation of cystathionine beta-synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 1 37,743,089 37,774,485 RGD:1624291
RGD:1600115
negative regulation of guanylate cyclase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hpca hippocalcin JBrowse link 5 147,295,124 147,305,757 RGD:9686438
G Pdzd3 PDZ domain containing 3 JBrowse link 8 48,577,905 48,582,353 RGD:1600115
G Rd3 retinal degeneration 3, GUCY2D regulator JBrowse link 13 110,739,645 110,749,167 RGD:1624291
RGD:1600115
negative regulation of lyase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Phpt1 phosphohistidine phosphatase 1 JBrowse link 3 2,797,037 2,798,436 RGD:8554604
RGD:1624291
positive regulation of aconitate hydratase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ftmt ferritin mitochondrial JBrowse link 18 47,294,292 47,295,541 RGD:1624291
RGD:1600115
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1624291
RGD:1600115
G Iscu iron-sulfur cluster assembly enzyme JBrowse link 12 48,621,454 48,627,297 RGD:1600115
RGD:1624291
positive regulation of adenylate cyclase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:8693686
G Akap5 A-kinase anchoring protein 5 JBrowse link 6 99,356,509 99,361,909 RGD:7242424
RGD:1600115
RGD:13792537
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:1600115
RGD:1624291
G Cacna1d calcium voltage-gated channel subunit alpha1 D JBrowse link 16 6,110,294 6,405,022 RGD:1600115
RGD:1624291
G Calcr calcitonin receptor JBrowse link 4 28,627,439 28,702,559 RGD:1624291
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:1624291
G Hpca hippocalcin JBrowse link 5 147,295,124 147,305,757 RGD:9686438
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Orai1 ORAI calcium release-activated calcium modulator 1 JBrowse link 12 38,981,903 38,995,570 RGD:1600115
RGD:1624291
G Stim1 stromal interaction molecule 1 JBrowse link 1 167,373,894 167,533,412 RGD:1600115
RGD:1624291
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:1598578
positive regulation of guanylate cyclase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1624291
RGD:1600115
G Guca1a guanylate cyclase activator 1A JBrowse link 9 15,609,804 15,620,030 RGD:1599357
G Guca1b guanylate cyclase activator 1B JBrowse link 9 15,621,083 15,629,017 RGD:1600115
G Guca2a guanylate cyclase activator 2A JBrowse link 5 138,685,634 138,687,476 RGD:1600115
G Guca2b guanylate cyclase activator 2B JBrowse link 5 138,695,591 138,697,641 RGD:1600115
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:13792537
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:13792537
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:1624291
RGD:13792537
RGD:1600115
positive regulation of L-dopa decarboxylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
positive regulation of lyase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ftmt ferritin mitochondrial JBrowse link 18 47,294,292 47,295,541 RGD:1624291
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1624291
regulation of adenylate cyclase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 JBrowse link 5 140,559,195 140,585,494 RGD:13792537
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 JBrowse link 17 18,441,614 18,592,866 RGD:13792537
G Gng7 G protein subunit gamma 7 JBrowse link 7 11,565,740 11,629,519 RGD:1624291
G Npffr2 neuropeptide FF receptor 2 JBrowse link 14 20,148,485 20,193,577 RGD:1600115
regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:1624291
regulation of ferrochelatase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1624291
RGD:1600115
regulation of guanylate cyclase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Guca1a guanylate cyclase activator 1A JBrowse link 9 15,609,804 15,620,030 RGD:1624291
G Guca1b guanylate cyclase activator 1B JBrowse link 9 15,621,083 15,629,017 RGD:1624291

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Term Annotations click to browse term
  biological_process 19317
    biological regulation 13340
      regulation of molecular function 3017
        regulation of catalytic activity 2298
          regulation of lyase activity 52
            negative regulation of lyase activity + 26
            positive regulation of lyase activity + 23
            regulation of L-dopa decarboxylase activity + 1
            regulation of aconitate hydratase activity + 3
            regulation of adenylate cyclase activity + 36
            regulation of cystathionine beta-synthase activity + 1
            regulation of ferrochelatase activity 1
            regulation of guanylate cyclase activity + 11
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.