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ONTOLOGY REPORT - ANNOTATIONS


Term:kinetochore assembly
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Accession:GO:0051382 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
Synonyms:narrow_synonym: centromere and kinetochore complex maturation;   centromere/kinetochore complex maturation;   chromosome-kinetochore attachment
 related_synonym: kinetochore formation
 alt_id: GO:0000069


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kinetochore assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CENPA centromere protein A ISO (PMID:11682612) BHF-UCL PMID:11682612 NCBI chr2A:26,785,301...26,800,178 JBrowse link
G CENPC centromere protein C ISO (PMID:21529714) UniProtKB PMID:21529714 NCBI chr 4:56,503,353...56,615,246
Ensembl chr 4:62,895,561...62,968,383
JBrowse link
G CENPE centromere protein E ISO (PMID:9763420) UniProt PMID:9763420 NCBI chr 4:95,562,005...95,654,397
Ensembl chr 4:106,185,283...106,277,229
JBrowse link
G CENPT centromere protein T ISO (PMID:21529714) UniProtKB PMID:21529714 NCBI chr16:48,169,892...48,177,559
Ensembl chr16:67,557,661...67,564,735
JBrowse link
G CENPW centromere protein W ISO (PMID:21695110) UniProtKB PMID:21695110 NCBI chr 6:124,125,492...124,272,450
Ensembl chr 6:128,242,724...128,251,528
JBrowse link
G MIS12 MIS12 kinetochore complex component ISO (PMID:16585270) UniProtKB PMID:16585270 NCBI chr17:5,534,305...5,538,736
Ensembl chr17:5,529,017...5,529,634
JBrowse link
G POGZ pogo transposable element derived with ZNF domain ISO (PMID:20562864) UniProtKB PMID:20562864 NCBI chr 1:126,761,777...126,818,262
Ensembl chr 1:130,407,426...130,463,909
JBrowse link
regulation of kinetochore assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RNF4 ring finger protein 4 ISO (PMID:20212317) UniProtKB PMID:20212317 NCBI chr 4:2,614,918...2,661,785
Ensembl chr 4:2,540,612...2,563,937
JBrowse link
G SENP6 SUMO specific peptidase 6 ISO (PMID:20212317) UniProtKB PMID:20212317 NCBI chr 6:73,445,608...73,562,018
Ensembl chr 6:76,736,477...76,852,422
JBrowse link
G TRAPPC12 trafficking protein particle complex 12 ISO (PMID:25918224) UniProtKB PMID:25918224 NCBI chr2A:3,388,191...3,490,496
Ensembl chr2A:3,311,765...3,411,768
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12529
    cellular process 11625
      cellular component organization or biogenesis 4979
        cellular component biogenesis 2352
          cellular component assembly 2238
            organelle assembly 714
              kinetochore assembly 10
                NMS complex assembly + 0
                negative regulation of kinetochore assembly + 0
                positive regulation of kinetochore assembly + 0
                protein localization to kinetochore involved in kinetochore assembly 0
                regulation of kinetochore assembly + 3
Path 2
Term Annotations click to browse term
  biological_process 12529
    cellular process 11625
      cellular component organization or biogenesis 4979
        cellular component organization 4899
          cellular component assembly 2238
            protein-containing complex assembly 1084
              cellular protein-containing complex assembly 697
                protein-DNA complex assembly 85
                  centromere complex assembly 17
                    kinetochore assembly 10
                      NMS complex assembly + 0
                      negative regulation of kinetochore assembly + 0
                      positive regulation of kinetochore assembly + 0
                      protein localization to kinetochore involved in kinetochore assembly 0
                      regulation of kinetochore assembly + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.