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ONTOLOGY REPORT - ANNOTATIONS


Term:kinetochore assembly
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Accession:GO:0051382 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
Synonyms:narrow_synonym: centromere and kinetochore complex maturation;   centromere/kinetochore complex maturation;   chromosome-kinetochore attachment
 related_synonym: kinetochore formation
 alt_id: GO:0000069


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kinetochore assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpa centromere protein A ISO (PMID:11682612) BHF-UCL PMID:11682612 NCBI chrNW_004955469:8,799,312...8,819,637 JBrowse link
G Cenpc centromere protein C ISO (PMID:21529714) UniProtKB PMID:21529714 NCBI chrNW_004955447:5,345,617...5,406,889 JBrowse link
G Cenpe centromere protein E ISO (PMID:9763420) UniProt PMID:9763420 NCBI chrNW_004955496:5,468,759...5,514,915 JBrowse link
G Cenpt centromere protein T ISO (PMID:21529714) UniProtKB PMID:21529714 NCBI chrNW_004955484:8,862,221...8,867,881 JBrowse link
G Cenpw centromere protein W ISO (PMID:21695110) UniProtKB PMID:21695110 NCBI chrNW_004955436:7,557,595...7,563,238 JBrowse link
G Mis12 MIS12 kinetochore complex component ISO (PMID:16585270) UniProtKB PMID:16585270 NCBI chrNW_004955467:10,837,570...10,842,131 JBrowse link
G Pogz pogo transposable element derived with ZNF domain ISO (PMID:20562864) UniProtKB PMID:20562864 NCBI chrNW_004955589:920,729...975,242 JBrowse link
regulation of kinetochore assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf4 ring finger protein 4 ISO (PMID:20212317) UniProtKB PMID:20212317 NCBI chrNW_004955514:1,501,943...1,525,689 JBrowse link
G Senp6 SUMO specific peptidase 6 ISO (PMID:20212317) UniProtKB PMID:20212317 NCBI chrNW_004955502:4,082,217...4,180,696 JBrowse link
G Trappc12 trafficking protein particle complex 12 ISO (PMID:25918224) UniProtKB PMID:25918224 NCBI chrNW_004955487:3,824,872...3,863,859 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11862
    cellular process 11059
      cellular component organization or biogenesis 4837
        cellular component biogenesis 2287
          cellular component assembly 2173
            organelle assembly 698
              kinetochore assembly 10
                NMS complex assembly + 0
                negative regulation of kinetochore assembly + 0
                positive regulation of kinetochore assembly + 0
                protein localization to kinetochore involved in kinetochore assembly 0
                regulation of kinetochore assembly + 3
Path 2
Term Annotations click to browse term
  biological_process 11862
    cellular process 11059
      cellular component organization or biogenesis 4837
        cellular component organization 4757
          cellular component assembly 2173
            protein-containing complex assembly 1038
              cellular protein-containing complex assembly 663
                protein-DNA complex assembly 76
                  centromere complex assembly 17
                    kinetochore assembly 10
                      NMS complex assembly + 0
                      negative regulation of kinetochore assembly + 0
                      positive regulation of kinetochore assembly + 0
                      protein localization to kinetochore involved in kinetochore assembly 0
                      regulation of kinetochore assembly + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.