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ONTOLOGY REPORT - ANNOTATIONS


Term:response to mineralocorticoid
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Accession:GO:0051385 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
Synonyms:exact_synonym: response to mineralocorticoid stimulus


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response to mineralocorticoid term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 IEP aldosterone RGD PMID:19521108 RGD:2314503 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 IEP aldosterone RGD PMID:23139218 RGD:9685409 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IEP RGD PMID:11882579 RGD:1626447 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP RGD PMID:20466875 RGD:2326033 NCBI chr13:90,722,945...90,753,338
Ensembl chr13:90,723,092...90,752,581
JBrowse link
G Kras KRAS proto-oncogene, GTPase IEP RGD PMID:16543373 RGD:1581767 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Nts neurotensin IEP RGD PMID:7623287 RGD:9698455 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Prss8 serine protease 8 IEP RGD PMID:17468916 RGD:2292488 NCBI chr 1:199,372,519...199,377,035
Ensembl chr 1:199,372,519...199,377,035
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:16157790 RGD:1601372 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
cellular response to aldosterone term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEP RGD PMID:11447075 RGD:12859284 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP RGD PMID:24551180 RGD:10047410 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 IEP RGD PMID:17644563 RGD:9686437 NCBI chr 7:12,851,730...12,870,087
Ensembl chr 7:12,851,739...12,874,215
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 IEP RGD PMID:17644563 RGD:9686437 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP RGD PMID:22173225 RGD:10045990 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha ISO (MGI:4456324|PMID:20427473) RGD PMID:20427473 MGI:4456324 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta ISO (MGI:4456324|PMID:20427473) RGD PMID:20427473 MGI:4456324 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma ISO (MGI:4456324|PMID:20427473) RGD PMID:20427473 MGI:4456324 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268
JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:26617694 RGD:11073721 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 ISO (MGI:4456324|PMID:20427473) RGD PMID:20427473 MGI:4456324 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
cellular response to corticosterone stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 IEP RGD PMID:10777776 RGD:2317731 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Foxo3 forkhead box O3 IEP RGD PMID:23494228 RGD:10402192 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP RGD PMID:19540859 RGD:13432032 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Lmnb1 lamin B1 IEP RGD PMID:15755911 RGD:2312627 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Npas4 neuronal PAS domain protein 4 ISO (MGI:4834977|PMID:20626564) RGD PMID:20626564 MGI:4834977 NCBI chr 1:220,260,310...220,278,177
Ensembl chr 1:220,261,008...220,265,772
JBrowse link
cellular response to mineralocorticoid stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 IEP aldosterone RGD PMID:19638349 RGD:8661802 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ep300 E1A binding protein p300 IEP 11-deoxycorticosterone RGD PMID:22465009 RGD:7327218 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IDA PMID:23283935 UniProt PMID:23283935 RGD:8553898 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Ran RAN, member RAS oncogene family IEP aldosterone RGD PMID:22811487 RGD:9835351 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
response to 11-deoxycorticosterone term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csn1s1 casein alpha s1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:21,993,450...22,009,308
Ensembl chr14:21,993,427...22,009,308
JBrowse link
G Hdac8 histone deacetylase 8 IDA RGD PMID:23868068 RGD:9681716 NCBI chr  X:72,163,777...72,370,058
Ensembl chr  X:72,163,777...72,370,044
JBrowse link
response to aldosterone term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain IEP RGD PMID:21824999 RGD:11040695 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain IEP RGD PMID:21824999 RGD:11040695 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IEP RGD PMID:14994994 RGD:10414067 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rpl27 ribosomal protein L27 IEP RGD PMID:24303148 RGD:11036077 NCBI chr10:89,352,864...89,356,563
Ensembl chr10:89,352,835...89,356,547
JBrowse link
response to corticosterone term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase IEP RGD PMID:17014691 RGD:2301035 NCBI chr10:105,568,091...105,572,407
Ensembl chr10:105,568,091...105,572,403
JBrowse link
G Agtr1a angiotensin II receptor, type 1a IEP RGD PMID:7594440 RGD:10047392 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IEP RGD PMID:15475662 RGD:2300330 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP RGD PMID:17562391 RGD:2293077 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP RGD PMID:17562391 RGD:2293077 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 IEP RGD PMID:8858202 RGD:2624129 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Calm2 calmodulin 2 IEP RGD PMID:16503919 RGD:6892959 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Ccnd1 cyclin D1 IEP RGD PMID:12807724 RGD:2289298 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 IEP RGD PMID:12807724 RGD:2289298 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP RGD PMID:17460069 RGD:2289669 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Crh corticotropin releasing hormone IEP RGD PMID:21664419 RGD:5490546 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 IEP RGD PMID:18335507 RGD:4831835 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:18485334 RGD:2293759 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:18485334 RGD:2293759 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit IEP RGD PMID:18485334 RGD:2293759 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Gpx3 glutathione peroxidase 3 IEP RGD PMID:15755911 RGD:2312627 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Hdac6 histone deacetylase 6 IMP RGD PMID:22331421 RGD:9681553 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 IEP RGD PMID:18335507 RGD:4831835 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:18335507, PMID:21873635 RGD:4831835, RGD:13792537
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:8027581, PMID:21873635 RGD:4889559, RGD:13792537 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:200,615,910...200,633,317
Ensembl chr 2:200,584,986...200,692,335
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IDA RGD PMID:19617650 RGD:6480668 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:18485334 RGD:2293759 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G LOC108348086 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:202,341,415...202,350,893
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Maob monoamine oxidase B IEP RGD PMID:15919584 RGD:2316762 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Mfn1 mitofusin 1 IEP RGD PMID:22244747 RGD:13204844 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Nefl neurofilament light IEP RGD PMID:17229084 RGD:2299003 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nos3 nitric oxide synthase 3 IEP RGD PMID:11304519 RGD:7794761 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP RGD PMID:16673181 RGD:4892105 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 IEP RGD PMID:14557907 RGD:2325630 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Nts neurotensin IEP RGD PMID:7623287 RGD:9698455 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 IEP RGD PMID:18311602 RGD:2302824 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Prkca protein kinase C, alpha IEP RGD PMID:17873323 RGD:2292475 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IEP RGD PMID:14663185 RGD:1599939 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IEP RGD PMID:18584335 RGD:2300226 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Reln reelin IEP RGD PMID:19477232 RGD:2317770 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Serpina7 serpin family A member 7 IEP RGD PMID:8365361 RGD:1600134 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Slc18a2 solute carrier family 18 member A2 IEP RGD PMID:19494803 RGD:5130973 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Star steroidogenic acute regulatory protein IEP RGD PMID:18335507 RGD:4831835 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Th tyrosine hydroxylase IEP RGD PMID:19494803 RGD:5130973 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Trh thyrotropin releasing hormone IEP RGD PMID:16293347 RGD:1600418 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
G Ucn3 urocortin 3 IEP RGD PMID:16809443 RGD:2306173 NCBI chr17:69,959,879...69,966,532
Ensembl chr17:69,960,160...69,966,099
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      response to endogenous stimulus 2028
        response to hormone 1213
          response to steroid hormone 517
            response to corticosteroid 330
              response to mineralocorticoid 75
                cellular response to mineralocorticoid stimulus + 19
                response to 11-deoxycorticosterone + 2
                response to aldosterone + 14
                response to corticosterone + 48
Path 2
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      response to chemical 6337
        response to organic substance 3864
          response to hormone 1213
            response to steroid hormone 517
              response to corticosteroid 330
                response to mineralocorticoid 75
                  cellular response to mineralocorticoid stimulus + 19
                  response to 11-deoxycorticosterone + 2
                  response to aldosterone + 14
                  response to corticosterone + 48
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.