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ONTOLOGY REPORT - ANNOTATIONS


Term:response to cortisol
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Accession:GO:0051414 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
Synonyms:exact_synonym: response to cortisol stimulus;   response to hydrocortisone stimulus


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response to cortisol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP RGD PMID:2353918 RGD:2303529 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 IEP RGD PMID:9886829 RGD:1626580 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Slit2 slit guidance ligand 2 IEA
ISO
GO_REF:0000107
(PMID:18566128)
Ensembl
RGD
PMID:18566128 GO_REF:0000107 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Slit3 slit guidance ligand 3 IEA
ISO
GO_REF:0000107
(PMID:18566128)
Ensembl
RGD
PMID:18566128 GO_REF:0000107 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link
G Tk1 thymidine kinase 1 IEP RGD PMID:7208144 RGD:2317233 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
cellular response to cortisol stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IEP RGD PMID:8674863 RGD:7829730 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Klf9 Kruppel-like factor 9 IEA
ISO
ISS
GO_REF:0000107
(PMID:22711835)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22711835 GO_REF:0000024, GO_REF:0000107 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to chemical 6343
        response to organic substance 3865
          response to ketone 406
            response to cortisol 7
              cellular response to cortisol stimulus 2
Path 2
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      response to chemical 6343
        response to organic substance 3865
          response to lipid 1388
            response to steroid hormone 517
              response to corticosteroid 330
                response to glucocorticoid 302
                  response to cortisol 7
                    cellular response to cortisol stimulus 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.