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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of ubiquitin-protein transferase activity
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Accession:GO:0051444 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.
Synonyms:exact_synonym: down regulation of ubiquitin transferase activity;   downregulation of ubiquitin transferase activity;   negative regulation of ubiquitin transferase activity
 narrow_synonym: APC inhibition;   APC inhibitor;   SCF complex inhibitor;   anaphase promoting complex inhibition;   anaphase promoting complex inhibitor;   inhibition of ubiquitin transferase activity;   ubiquitin transferase inhibitor


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negative regulation of ubiquitin-protein transferase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO (PMID:20823226) RGD PMID:20823226 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Bag5 BAG cochaperone 5 IDA PMID:15603737 BHF-UCL PMID:15603737 RGD:8553807 NCBI chr 6:136,180,640...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Bag5l1 BCL2-associated athanogene 5-like 1 IDA PMID:15603737 BHF-UCL PMID:15603737 RGD:8553807 NCBI chr 6:136,274,351...136,279,414
Ensembl chr 6:136,182,006...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO (MGI:MGI:1327100|PMID:9878046) RGD PMID:9878046 MGI:MGI:1327100 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L ISO (PMID:24790097) RGD PMID:24790097 NCBI chr11:67,758,093...67,767,623
NCBI chr11:67,768,542...67,772,428
Ensembl chr11:67,757,928...67,767,622
JBrowse link
G Fbxo5 F-box protein 5 ISO (PMID:23708001) RGD PMID:23708001 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Limk1 LIM domain kinase 1 ISO
IEA
(PMID:17512523)
GO_REF:0000107
RGD
Ensembl
PMID:17512523 GO_REF:0000107 NCBI chr12:25,036,630...25,070,538
Ensembl chr12:25,036,605...25,070,539
JBrowse link
G Park7 Parkinsonism associated deglycase ISO
IEA
(PMID:24899725)
GO_REF:0000107
RGD
Ensembl
PMID:24899725 GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Psen1 presenilin 1 ISO (MGI:MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:MGI:4887523 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Psen2 presenilin 2 ISO (MGI:MGI:4887523|PMID:20208556) RGD PMID:20208556 MGI:MGI:4887523 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Smad7 SMAD family member 7 ISO
IEA
(PMID:18593713)
GO_REF:0000107
RGD
Ensembl
PMID:18593713 GO_REF:0000107 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
negative regulation of ubiquitin protein ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag2 BAG cochaperone 2 ISO (PMID:16207813) RGD PMID:16207813 NCBI chr 9:38,456,487...38,467,120
Ensembl chr 9:38,456,468...38,467,118
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO (PMID:18560357) RGD PMID:18560357 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Fbxo5 F-box protein 5 ISO (PMID:11988738), (PMID:16921029), (PMID:23708605), (PMID:29875408) RGD PMID:11988738, PMID:16921029, PMID:23708605, PMID:29875408 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO (PMID:11459825) RGD PMID:11459825 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO
ISS
(PMID:11459826)
GO_REF:0000024
RGD
UniProt
PMID:11459826 GO_REF:0000024 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Rpl11 ribosomal protein L11 ISO (PMID:18560357) RGD PMID:18560357 NCBI chr 5:154,390,809...154,394,412
Ensembl chr 5:154,388,140...154,394,328
JBrowse link
G Rpl23 ribosomal protein L23 ISO (PMID:15314173) RGD PMID:15314173 NCBI chr10:85,721,398...85,725,359
Ensembl chr10:85,721,394...85,725,429
JBrowse link
G Rpl5 ribosomal protein L5 ISO (PMID:18560357) RGD PMID:18560357 NCBI chr14:2,860,963...2,867,397
Ensembl chr14:2,860,965...2,867,397
JBrowse link
G Rps7 ribosomal protein S7 ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G Usp44 ubiquitin specific peptidase 44 ISO (PMID:17443180) RGD PMID:17443180 NCBI chr 7:34,714,293...34,759,352
Ensembl chr 7:34,744,483...34,759,206
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of molecular function 3077
        regulation of catalytic activity 2344
          negative regulation of catalytic activity 854
            negative regulation of transferase activity 291
              negative regulation of ubiquitin-protein transferase activity 19
                negative regulation of ubiquitin protein ligase activity 10
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          protein metabolic process 6264
            protein modification process 3949
              cellular protein modification process 3949
                protein modification by small protein conjugation or removal 952
                  protein modification by small protein conjugation 816
                    protein ubiquitination 767
                      regulation of protein ubiquitination 212
                        negative regulation of protein ubiquitination 84
                          negative regulation of ubiquitin-protein transferase activity 19
                            negative regulation of ubiquitin protein ligase activity 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.