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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular pH elevation
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Accession:GO:0051454 term browser browse the term
Definition:Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.
Synonyms:exact_synonym: cell pH elevation;   cellular alkalinization;   elevation of cellular pH;   intracellular alkalinization;   pH elevation in cell


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intracellular pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5429843|PMID:21976599)
Ensembl
UniProt
RGD
PMID:21976599 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5429843 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Nox1 NADPH oxidase 1 ISO
IEA
(PMID:10615049)
GO_REF:0000107
RGD
Ensembl
PMID:10615049 GO_REF:0000107 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Slc26a3 solute carrier family 26 member 3 ISO
ISS
(MGI:MGI:5429843|PMID:21976599)
GO_REF:0000024
RGD
UniProt
PMID:21976599 GO_REF:0000024, MGI:MGI:5429843 NCBI chr 6:50,725,085...50,766,306
Ensembl chr 6:50,725,085...50,766,300
JBrowse link
G Slc26a6 solute carrier family 26 member 6 ISO (MGI:MGI:5429843|PMID:21976599) RGD PMID:21976599 MGI:MGI:5429843 NCBI chr 8:117,648,792...117,659,376
Ensembl chr 8:117,648,745...117,659,804
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin ISO
ISS
(PMID:10924275)
GO_REF:0000024
RGD
UniProt
PMID:10924275 GO_REF:0000024 NCBI chr 1:197,986,384...197,999,726
Ensembl chr 1:197,986,385...197,997,664
JBrowse link
negative regulation of cellular pH reduction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator IEA
ISO
GO_REF:0000107
(PMID:10506221)
Ensembl
RGD
PMID:10506221 GO_REF:0000107 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular homeostasis 1035
        cellular chemical homeostasis 949
          cellular ion homeostasis 730
            cellular cation homeostasis 717
              cellular monovalent inorganic cation homeostasis 109
                regulation of cellular pH 83
                  regulation of intracellular pH 74
                    intracellular pH elevation 6
                      lysosomal lumen pH elevation 1
                      negative regulation of cellular pH reduction + 1
                      phagosome reneutralization 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological quality 4280
        homeostatic process 2077
          chemical homeostasis 1334
            ion homeostasis 887
              cellular ion homeostasis 730
                cellular cation homeostasis 717
                  cellular monovalent inorganic cation homeostasis 109
                    regulation of cellular pH 83
                      regulation of intracellular pH 74
                        intracellular pH elevation 6
                          lysosomal lumen pH elevation 1
                          negative regulation of cellular pH reduction + 1
                          phagosome reneutralization 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.