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ONTOLOGY REPORT - ANNOTATIONS


Term:cytosine C-5 DNA demethylase activity
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Accession:GO:0051747 term browser browse the term
Definition:Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.
Synonyms:exact_synonym: DNA methyltransferase activity acting on cytosine C-5
 broad_synonym: DNA demethylase activity;   hydrolytic DNA demethylase activity


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cytosine C-5 DNA demethylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase JBrowse link 12 48,257,575 48,262,244 RGD:1624291
RGD:13792537
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase JBrowse link 3 82,874,242 82,907,467 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19528
    catalytic activity 6039
      hydrolase activity 2608
        cytosine C-5 DNA demethylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 19528
    catalytic activity 6039
      demethylase activity 40
        DNA demethylase activity 5
          cytosine C-5 DNA demethylase activity 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.