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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synapse structural plasticity
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Accession:GO:0051823 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane.
Synonyms:exact_synonym: regulation of synaptic structural plasticity


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regulation of synapse structural plasticity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnna2 catenin alpha 2 ISO (MGI:3628965|PMID:15034585) RGD PMID:15034585 MGI:3628965 NCBI chr 4:107,880,611...109,042,724
Ensembl chr 4:107,881,826...108,008,484
JBrowse link
G Dmpk DM1 protein kinase ISO (MGI:3608373|PMID:12612014) RGD PMID:12612014 MGI:3608373 NCBI chr 1:79,988,096...79,999,358
Ensembl chr 1:79,989,019...79,999,364
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:22216301 RGD:6907446 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Ncan neurocan ISO MGI:2182149 (MGI:2148397|PMID:11486035) RGD PMID:11486035 MGI:2148397 NCBI chr16:21,050,243...21,076,707
Ensembl chr16:21,050,243...21,076,707
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:15473970 RGD:10043779 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
positive regulation of synapse structural plasticity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk1 calcium/calmodulin-dependent protein kinase I ISO
ISS
(PMID:18184567)
GO_REF:0000024
RGD
UniProt
PMID:18184567 GO_REF:0000024 NCBI chr 4:145,289,300...145,300,146
Ensembl chr 4:145,288,996...145,300,177
JBrowse link
G Cdc42 cell division cycle 42 IMP RGD PMID:21423166 RGD:5688281 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Frmpd4 FERM and PDZ domain containing 4 ISO (PMID:19118189) RGD PMID:19118189 NCBI chr  X:27,231,648...28,206,890
Ensembl chr  X:28,072,826...28,204,260
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 ISS
ISO
IEA
GO_REF:0000024
(MGI:5285139|PMID:21167025)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:21167025 GO_REF:0000024, GO_REF:0000107, MGI:5285139 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      regulation of cellular process 12556
        regulation of cellular component organization 2565
          regulation of synapse organization 266
            regulation of synapse structural plasticity 9
              negative regulation of synapse structural plasticity 0
              positive regulation of synapse structural plasticity 4
Path 2
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          cell junction organization 794
            synapse organization 509
              regulation of synapse organization 266
                regulation of synapse structural plasticity 9
                  negative regulation of synapse structural plasticity 0
                  positive regulation of synapse structural plasticity 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.