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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial depolarization
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Accession:GO:0051882 term browser browse the term
Definition:The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
Synonyms:exact_synonym: mitochondria depolarization;   mitochondrial depolarisation;   mitochondrial membrane depolarization;   mitochondrion depolarization


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mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Casp1 caspase 1 ISO
IEA
(MGI:MGI:5466421|PMID:23028046)
GO_REF:0000107
RGD
Ensembl
PMID:23028046 GO_REF:0000107, MGI:MGI:5466421 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO (PMID:25217637) RGD PMID:25217637 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK ISO (MGI:MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:MGI:5796062 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:29215467 RGD:13504824 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Hsh2d hematopoietic SH2 domain containing ISO (MGI:MGI:3574118|PMID:15569688) RGD PMID:15569688 MGI:MGI:3574118 NCBI chr16:19,336,400...19,349,868
Ensembl chr16:19,336,271...19,349,080
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:19457114 RGD:5508731 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:19767770) RGD PMID:19767770 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15564577 RGD:2313870 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Cck cholecystokinin IDA apoptotic RGD PMID:11964411 RGD:625521 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Dcn decorin ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Kdr kinase insert domain receptor ISO
IEA
UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107
RGD
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor ISO
IBA
ISS
(PMID:18852119)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:18852119, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G Myoc myocilin IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17516541)
Ensembl
UniProt
RGD
PMID:17516541 GO_REF:0000024, GO_REF:0000107 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:19139380 RGD:2305938 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO MGI:MGI:2386080 (MGI:MGI:3607437|PMID:16198349) RGD PMID:16198349 MGI:MGI:3607437 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP protein:increased activity:brain: RGD PMID:21616968 RGD:10413888 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rack1 receptor for activated C kinase 1 ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Tspo translocator protein IDA RGD PMID:15183124 RGD:2317155 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO (MGI:MGI:5790173|PMID:25583114) RGD PMID:25583114 MGI:MGI:5790173 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO MGI:MGI:104995 (MGI:MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:MGI:3047441 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit ISO MGI:MGI:104990 (MGI:MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:MGI:3047441 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:22736029) RGD PMID:22736029 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma ISO MGI:MGI:3759678 (MGI:MGI:3589325|PMID:16129705) RGD PMID:16129705 MGI:MGI:3589325 NCBI chr 6:76,056,585...76,079,755
Ensembl chr 6:76,056,499...76,079,664
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological quality 4284
        regulation of membrane potential 483
          membrane depolarization 85
            mitochondrial depolarization 24
              negative regulation of mitochondrial depolarization 5
              positive regulation of mitochondrial depolarization 11
              regulation of mitochondrial depolarization + 21
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.