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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane depolarization
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Accession:GO:0051899 term browser browse the term
Definition:The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.


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membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP RGD PMID:16644907 RGD:1625443 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Best2 bestrophin 2 ISO (MGI:MGI:3763293|PMID:16912113) RGD PMID:16912113 MGI:MGI:3763293 NCBI chr19:26,122,869...26,129,619
Ensembl chr19:26,122,881...26,129,619
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA
ISO
GO_REF:0000107
MGI:MGI:1856209|MGI:MGI:1856210|MGI:MGI:1856211 (MGI:MGI:1861319|PMID:10908603), (MGI:MGI:2153687|PMID:11718712), (MGI:MGI:66121|PMID:8158221)
Ensembl
RGD
PMID:8158221, PMID:10908603, PMID:11718712 GO_REF:0000107, MGI:MGI:1861319, MGI:MGI:2153687, MGI:MGI:66121 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO MGI:MGI:1856548 (MGI:MGI:708065|PMID:9065835) RGD PMID:9065835 MGI:MGI:708065 NCBI chr 7:119,228,112...119,353,332
Ensembl chr 7:119,228,102...119,352,605
JBrowse link
G Cav1 caveolin 1 ISO
IEA
MGI:MGI:2180364 (MGI:MGI:3707284|PMID:17098833)
GO_REF:0000107
RGD
Ensembl
PMID:17098833 GO_REF:0000107, MGI:MGI:3707284 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit IEA
ISO
GO_REF:0000107
MGI:MGI:1926251|MGI:MGI:2158758|MGI:MGI:87891 (MGI:MGI:1931636|PMID:11226318), (MGI:MGI:2673776|PMID:12944511), (MGI:MGI:3581093|PMID:15741168), (MGI:MGI:3628837|PMID:11222635)
Ensembl
RGD
PMID:11222635, PMID:11226318, PMID:12944511, PMID:15741168 GO_REF:0000107, MGI:MGI:1931636, MGI:MGI:2673776, MGI:MGI:3581093, MGI:MGI:3628837 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit ISO
IEA
MGI:MGI:2179133 (MGI:MGI:2673776|PMID:12944511)
GO_REF:0000107
RGD
Ensembl
PMID:12944511 GO_REF:0000107, MGI:MGI:2673776 NCBI chr16:68,860,018...68,866,718
Ensembl chr16:68,860,018...68,866,718
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:MGI:1926253 (MGI:MGI:3628837|PMID:11222635) RGD PMID:11222635 MGI:MGI:3628837 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 IDA RGD PMID:18048449 RGD:6902904 NCBI chr14:38,155,771...38,171,107
Ensembl chr14:38,155,759...38,171,010
JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 IDA RGD PMID:18048449 RGD:6902904 NCBI chr16:69,878,513...69,899,075 JBrowse link
G Edn1 endothelin 1 IMP RGD PMID:15655307 RGD:1580292 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 ISO MGI:MGI:2176347 (MGI:MGI:3769099|PMID:17245443) RGD PMID:17245443 MGI:MGI:3769099 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grm1 glutamate metabotropic receptor 1 TAS PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA induced in pulmonary artery smooth muscle cells RGD PMID:11571252 RGD:2290591 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kmt2a lysine methyltransferase 2A IEP RGD PMID:20211609 RGD:9588219 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G P2rx4 purinergic receptor P2X 4 ISO (PMID:9016352) RGD PMID:9016352 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO
IEA
IDA
(PMID:9038151)
GO_REF:0000107
PMID:8614837
RGD
Ensembl
PMID:9038151, PMID:8614837 GO_REF:0000107, RGD:69918 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Park7 Parkinsonism associated deglycase ISO MGI:MGI:3579140 (MGI:MGI:3653054|PMID:16624565) RGD PMID:16624565 MGI:MGI:3653054 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Prkcz protein kinase C, zeta IMP RGD PMID:15381257 RGD:1642699 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 ISO (PMID:21051419) RGD PMID:21051419 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO (PMID:21051419) RGD PMID:21051419 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISS
ISO
GO_REF:0000024
(PMID:14500339), (PMID:21051419), (PMID:21895525)
BHF-UCL
RGD
PMID:14500339, PMID:21051419, PMID:21895525 GO_REF:0000024 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Snap91 synaptosome associated protein 91 IEP RGD PMID:11779129 RGD:70605 NCBI chr 8:94,447,558...94,564,772
Ensembl chr 8:94,447,550...94,564,525
JBrowse link
membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1g calcium voltage-gated channel subunit alpha1 G IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 ISO
IEA
(PMID:7604285)
GO_REF:0000107
RGD
Ensembl
PMID:7604285 GO_REF:0000107 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:128,450,793...128,527,510
Ensembl chr 8:128,450,801...128,521,109
JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:52,388,811...52,533,365
Ensembl chr 3:52,381,975...52,510,507
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:51,687,910...51,822,008
Ensembl chr 3:51,687,809...51,822,250
JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:51,530,897...51,643,140
Ensembl chr 3:51,532,627...51,643,140
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO (PMID:20042427), (PMID:20226894), (PMID:21051419) RGD PMID:20042427, PMID:20226894, PMID:21051419 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn4a sodium voltage-gated channel alpha subunit 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:94,505,026...94,557,803
Ensembl chr10:94,505,026...94,557,764
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:14500339), (PMID:18065446), (PMID:22529811)
BHF-UCL
RGD
PMID:14500339, PMID:18065446, PMID:22529811, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:52,775,779...52,877,365
Ensembl chr 3:52,777,214...52,849,907
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:52,583,953...52,664,209
Ensembl chr 3:52,583,951...52,664,209
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta ISO
ISS
IEA
(PMID:16728661)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:16728661 GO_REF:0000024, GO_REF:0000107 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO
ISS
IEA
(PMID:17224476)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:17224476 GO_REF:0000024, GO_REF:0000107 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO
ISS
IEA
(PMID:17224476)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:17224476 GO_REF:0000024, GO_REF:0000107 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
IEA
(PMID:18065446)
GO_REF:0000107
RGD
Ensembl
PMID:18065446 GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
membrane depolarization during AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO
ISS
IEA
(PMID:26253506)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:26253506 GO_REF:0000024, GO_REF:0000107 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO
ISS
IEA
(MGI:MGI:3714901|PMID:16690884)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:16690884 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3714901 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO
ISS
IEA
(PMID:17224476)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:17224476 GO_REF:0000024, GO_REF:0000107 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
IEA
ISS
(PMID:18616619)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:18616619 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IEA
ISO
GO_REF:0000107
(PMID:27207958)
Ensembl
RGD
PMID:27207958 GO_REF:0000107 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IEA
ISO
GO_REF:0000107
(PMID:21383000)
Ensembl
RGD
PMID:21383000 GO_REF:0000107 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
IEA
ISS
(PMID:18065446)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:18065446 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IEA
ISO
GO_REF:0000107
(PMID:27207958)
Ensembl
RGD
PMID:27207958 GO_REF:0000107 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO
ISS
(PMID:15454078)
GO_REF:0000024
RGD
BHF-UCL
PMID:15454078 GO_REF:0000024 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IC PMID:21859974 BHF-UCL PMID:21859974 RGD:6767284 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 ISO (MGI:MGI:3763979|PMID:17884088) RGD PMID:17884088 MGI:MGI:3763979 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 ISO (PMID:19808477) RGD PMID:19808477 NCBI chr 8:49,419,003...49,431,110
Ensembl chr 8:49,418,965...49,427,689
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO (PMID:21051419) RGD PMID:21051419 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 ISO (PMID:17592081) RGD PMID:17592081 NCBI chr 8:49,441,106...49,456,279
Ensembl chr 8:49,441,106...49,456,279
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
ISS
(PMID:21895525)
GO_REF:0000024
RGD
BHF-UCL
PMID:21895525 GO_REF:0000024 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
membrane depolarization during Purkinje myocyte cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn1b sodium voltage-gated channel beta subunit 1 ISO (PMID:18464934) RGD PMID:18464934 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
IEA
ISS
(PMID:22766342)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:22766342 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IEA
ISO
GO_REF:0000107
(PMID:27207958)
Ensembl
RGD
PMID:27207958 GO_REF:0000107 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO
IEA
MGI:MGI:2180141 (MGI:MGI:3583874|PMID:12700358)
GO_REF:0000107
(PMID:21131953)
RGD
Ensembl
PMID:12700358, PMID:21131953 GO_REF:0000107, MGI:MGI:3583874 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO
ISS
IEA
(MGI:MGI:3714901|PMID:16690884)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:16690884 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3714901 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 IEA
ISO
GO_REF:0000107
(PMID:16407510)
Ensembl
RGD
PMID:16407510 GO_REF:0000107 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISO
IEA
ISS
(PMID:18616619)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
BHF-UCL
PMID:18616619 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Casp1 caspase 1 ISO
IEA
(MGI:MGI:5466421|PMID:23028046)
GO_REF:0000107
RGD
Ensembl
PMID:23028046 GO_REF:0000107, MGI:MGI:5466421 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO (PMID:25217637) RGD PMID:25217637 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 ISO (MGI:MGI:5613732|PMID:25257915) RGD PMID:25257915 MGI:MGI:5613732 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK ISO (MGI:MGI:5796062|PMID:27098698) RGD PMID:27098698 MGI:MGI:5796062 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:29215467 RGD:13504824 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Hsh2d hematopoietic SH2 domain containing ISO (MGI:MGI:3574118|PMID:15569688) RGD PMID:15569688 MGI:MGI:3574118 NCBI chr16:19,336,400...19,349,868
Ensembl chr16:19,336,271...19,349,080
JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:19457114 RGD:5508731 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO (PMID:19767770) RGD PMID:19767770 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 IMP PMID:18180363 BHF-UCL PMID:18180363 RGD:6767295 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15564577 RGD:2313870 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Cck cholecystokinin IDA apoptotic RGD PMID:11964411 RGD:625521 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Dcn decorin ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Kdr kinase insert domain receptor ISO
IEA
UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107
RGD
Ensembl
PMID:23798385 GO_REF:0000107 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor ISO
IBA
ISS
(PMID:18852119)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:18852119, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G Myoc myocilin IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:17516541)
Ensembl
UniProt
RGD
PMID:17516541 GO_REF:0000024, GO_REF:0000107 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:19139380 RGD:2305938 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO MGI:MGI:2386080 (MGI:MGI:3607437|PMID:16198349) RGD PMID:16198349 MGI:MGI:3607437 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP protein:increased activity:brain: RGD PMID:21616968 RGD:10413888 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Rack1 receptor for activated C kinase 1 ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Tspo translocator protein IDA RGD PMID:15183124 RGD:2317155 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:20826763 RGD:10003037 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
regulation of atrial cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1g calcium voltage-gated channel subunit alpha1 G ISO
IEA
MGI:MGI:2182962 (MGI:MGI:3714901|PMID:16690884)
GO_REF:0000107
RGD
Ensembl
PMID:16690884 GO_REF:0000107, MGI:MGI:3714901 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO MGI:MGI:1857177 (MGI:MGI:3639795|PMID:10969038) RGD PMID:10969038 MGI:MGI:3639795 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 ISO (PMID:22247482), (PMID:23348765)
MGI:MGI:2445238 (MGI:MGI:1197846|PMID:9501070), (MGI:MGI:3639795|PMID:10969038), (MGI:MGI:3696497|PMID:10515563)
RGD PMID:9501070, PMID:10515563, PMID:10969038, PMID:22247482, PMID:23348765 MGI:MGI:1197846, MGI:MGI:3639795, MGI:MGI:3696497 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 ISO MGI:MGI:2180183 (MGI:MGI:4848026|PMID:20062061)
(PMID:20062061), (PMID:21041692)
RGD PMID:20062061, PMID:21041692 MGI:MGI:4848026 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 ISO (PMID:19808477), (PMID:22247482) RGD PMID:19808477, PMID:22247482 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 ISO (PMID:19808477) RGD PMID:19808477 NCBI chr 8:49,419,003...49,431,110
Ensembl chr 8:49,418,965...49,427,689
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO (PMID:21051419)
(MGI:MGI:5294533|PMID:19796257)
RGD PMID:19796257, PMID:21051419 MGI:MGI:5294533 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:19167345), (PMID:22247482)
BHF-UCL
Ensembl
RGD
PMID:19167345, PMID:22247482, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
regulation of membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin ISO (PMID:23144825) RGD PMID:23144825 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta ISO (PMID:22514276) RGD PMID:22514276 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Cftr CF transmembrane conductance regulator NOT ISO (MGI:MGI:5640937|PMID:24885604) RGD PMID:24885604 MGI:MGI:5640937 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Fgf12 fibroblast growth factor 12 IDA PMID:12401812 BHF-UCL PMID:12401812 RGD:6484231 NCBI chr11:75,606,360...76,171,078
Ensembl chr11:75,905,443...76,168,989
JBrowse link
G Fhl1 four and a half LIM domains 1 ISO
IEA
(PMID:18281375)
GO_REF:0000107
RGD
Ensembl
PMID:18281375 GO_REF:0000107 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IDA RGD PMID:20806410 RGD:9686372 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 ISO
IEA
(PMID:12750403)
GO_REF:0000107
RGD
Ensembl
PMID:12750403 GO_REF:0000107 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase ISO (PMID:15217910) RGD PMID:15217910 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Npff neuropeptide FF-amide peptide precursor IDA RGD PMID:17289819 RGD:2316567 NCBI chr 7:144,127,084...144,127,873
Ensembl chr 7:144,127,085...144,127,873
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:15120846 RGD:9743930 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Rangrf RAN guanine nucleotide release factor ISO (MGI:MGI:5508678|PMID:23420830)
(PMID:18184654), (PMID:23420830)
RGD PMID:18184654, PMID:23420830 MGI:MGI:5508678 NCBI chr10:55,559,049...55,560,420
Ensembl chr10:55,559,041...55,560,422
JBrowse link
regulation of membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 ISO (PMID:16930557) RGD PMID:16930557 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
JBrowse link
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 ISO
IBA
(PMID:17275750)
PMID:21873635
RGD PMID:17275750, PMID:21873635 RGD:13792537 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Gja5 gap junction protein, alpha 5 ISO MGI:MGI:2445238 (MGI:MGI:1197846|PMID:9501070) RGD PMID:9501070 MGI:MGI:1197846 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Rangrf RAN guanine nucleotide release factor ISO (PMID:21621375) RGD PMID:21621375 NCBI chr10:55,559,049...55,560,420
Ensembl chr10:55,559,041...55,560,422
JBrowse link
G Slmap sarcolemma associated protein ISO
IEA
(PMID:23064965)
GO_REF:0000107
RGD
Ensembl
PMID:23064965 GO_REF:0000107 NCBI chr16:2,112,271...2,227,336
Ensembl chr16:2,112,274...2,227,309
JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 ISO (MGI:MGI:5790173|PMID:25583114) RGD PMID:25583114 MGI:MGI:5790173 NCBI chr  X:157,073,860...157,095,652
Ensembl chr  X:157,072,736...157,095,274
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO MGI:MGI:104995 (MGI:MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:MGI:3047441 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit ISO MGI:MGI:104990 (MGI:MGI:3047441|PMID:15288121) RGD PMID:15288121 MGI:MGI:3047441 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO (PMID:22736029) RGD PMID:22736029 NCBI chr 7:132,857,311...133,018,549
Ensembl chr 7:132,857,628...133,018,584
JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma ISO MGI:MGI:3759678 (MGI:MGI:3589325|PMID:16129705) RGD PMID:16129705 MGI:MGI:3589325 NCBI chr 6:76,056,585...76,079,755
Ensembl chr 6:76,056,499...76,079,664
JBrowse link
regulation of ventricular cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 ISO (PMID:17060380) RGD PMID:17060380 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO MGI:MGI:1857177|MGI:MGI:95716 (MGI:MGI:3639795|PMID:10969038), (MGI:MGI:86953|PMID:9109444) RGD PMID:9109444, PMID:10969038 MGI:MGI:3639795, MGI:MGI:86953 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gja5 gap junction protein, alpha 5 ISO MGI:MGI:2445238|MGI:MGI:95713 (MGI:MGI:1197846|PMID:9501070), (MGI:MGI:3639795|PMID:10969038), (MGI:MGI:3696497|PMID:10515563) RGD PMID:9501070, PMID:10515563, PMID:10969038 MGI:MGI:1197846, MGI:MGI:3639795, MGI:MGI:3696497 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1-like ISO (PMID:17967977), (PMID:19666841) RGD PMID:17967977, PMID:19666841 NCBI chr 8:122,957,570...122,987,236
Ensembl chr 8:122,954,948...122,987,191
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 ISO (PMID:20042427) RGD PMID:20042427 NCBI chr 8:44,136,413...44,159,011
Ensembl chr 8:44,136,496...44,159,010
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:18065446), (PMID:22529811), (PMID:7889574)
BHF-UCL
Ensembl
RGD
PMID:7889574, PMID:18065446, PMID:22529811 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological quality 4280
        regulation of membrane potential 483
          membrane depolarization 85
            membrane depolarization during action potential + 31
            mitochondrial depolarization + 24
            negative regulation of membrane depolarization + 6
            positive regulation of membrane depolarization + 13
            regulation of membrane depolarization + 46
            regulation of vascular associated smooth muscle cell membrane depolarization + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.