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Term:synaptic transmission, GABAergic
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Accession:GO:0051932 term browser browse the term
Definition:The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Synonyms:exact_synonym: synaptic transmission, GABA mediated;   synaptic transmission, gamma-aminobutyric acid mediated;   synaptic transmission, gamma-aminobutyric acid-ergic


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synaptic transmission, GABAergic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1a calcium voltage-gated channel subunit alpha1 A JBrowse link 19 25,453,236 25,749,550 RGD:1624291
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:1624291
G Clcn3 chloride voltage-gated channel 3 JBrowse link 16 32,448,821 32,520,649 RGD:1624291
G Clstn3 calsyntenin 3 JBrowse link 4 157,044,736 157,078,013 RGD:1624291
RGD:1600115
G Dnm1 dynamin 1 JBrowse link 3 11,338,081 11,382,043 RGD:1624291
G Gabra1 gamma-aminobutyric acid type A receptor alpha1 subunit JBrowse link 10 27,310,718 27,371,802 RGD:8554754
RGD:13792537
G Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit JBrowse link 14 39,662,411 39,801,082 RGD:13792537
G Gabra3 gamma-aminobutyric acid type A receptor alpha3 subunit JBrowse link X 152,414,332 152,642,607 RGD:13792537
G Gabra4 gamma-aminobutyric acid type A receptor alpha4 subunit JBrowse link 14 39,154,072 39,230,994 RGD:13792537
G Gabra5 gamma-aminobutyric acid type A receptor alpha 5 subunit JBrowse link 1 112,833,941 112,947,482 RGD:13792537
G Gabra6 gamma-aminobutyric acid type A receptor alpha 6 subunit JBrowse link 10 27,847,447 27,862,896 RGD:1626493
RGD:13792537
G Gabrb2 gamma-aminobutyric acid type A receptor beta 2 subunit JBrowse link 10 27,973,694 28,193,072 RGD:8554754
G Gabrb3 gamma-aminobutyric acid type A receptor beta 3 subunit JBrowse link 1 113,034,251 113,265,364 RGD:727440
G Gabre gamma-aminobutyric acid type A receptor epsilon subunit JBrowse link X 152,220,180 152,237,347 RGD:13792537
G Gabrg1 gamma-aminobutyric acid type A receptor gamma 1 subunit JBrowse link 14 39,964,502 40,051,306 RGD:13792537
G Gabrg2 gamma-aminobutyric acid type A receptor gamma 2 subunit JBrowse link 10 27,090,913 27,179,786 RGD:8554754
RGD:13792537
G Gabrg3 gamma-aminobutyric acid type A receptor gamma 3 subunit JBrowse link 1 112,158,525 112,812,267 RGD:13792537
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:8553469
G Grm4 glutamate metabotropic receptor 4 JBrowse link 20 6,745,682 6,791,521 RGD:8554275
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:1624291
G Rac3 Rac family small GTPase 3 JBrowse link 10 109,903,920 109,906,596 RGD:1624291
gamma-aminobutyric acid secretion, neurotransmission term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:1624291
negative regulation of synaptic transmission, GABAergic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:1625273
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:1624291
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:2316192
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1642497
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:1626455
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:1625505
G Slc6a1 solute carrier family 6 member 1 JBrowse link 4 146,258,842 146,292,176 RGD:1643193
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:1624291
RGD:1600115
positive regulation of synaptic transmission, GABAergic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1624291
RGD:1600115
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:1625778
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:1624291
RGD:1600115
G Car7 carbonic anhydrase 7 JBrowse link 19 636,545 645,935 RGD:1624291
RGD:1600115
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:2311326
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:2289989
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1642497
RGD:1624291
G Hap1 huntingtin-associated protein 1 JBrowse link 10 88,257,975 88,266,210 RGD:10047142
G Kif5b kinesin family member 5B JBrowse link 17 54,181,416 54,219,048 RGD:1624291
RGD:1600115
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8554754
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:1624291
RGD:1600115
G Nps neuropeptide S JBrowse link 1 207,508,414 207,512,195 RGD:1624291
RGD:13792537
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:2304220
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:2304250
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:2304250
regulation of synaptic transmission, GABAergic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2314643
G Cntnap4 contactin associated protein-like 4 JBrowse link 19 44,817,727 45,118,133 RGD:1624291
RGD:1600115
G Dbi diazepam binding inhibitor, acyl-CoA binding protein JBrowse link 13 36,147,667 36,156,076 RGD:8554715
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
RGD:1600115
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:1624291
RGD:1600115
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:1624291
RGD:1600115
G Nisch nischarin JBrowse link 16 7,254,372 7,290,670 RGD:1582692
G Npas4 neuronal PAS domain protein 4 JBrowse link 1 220,260,310 220,278,177 RGD:1624291
RGD:1600115
G Phf24 PHD finger protein 24 JBrowse link 5 58,359,744 58,387,446 RGD:1624291
RGD:1600115
G Plcl1 phospholipase C-like 1 JBrowse link 9 62,016,112 62,349,244 RGD:1600115
RGD:1624291
G Plcl2 phospholipase C-like 2 JBrowse link 9 1,782,536 1,984,654 RGD:1624291
RGD:1600115
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115
G Usp46 ubiquitin specific peptidase 46 JBrowse link 14 36,687,134 36,755,360 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17883
    signaling 7034
      cell-cell signaling 1595
        synaptic signaling 866
          trans-synaptic signaling 857
            anterograde trans-synaptic signaling 848
              chemical synaptic transmission 848
                synaptic transmission, GABAergic 58
                  gamma-aminobutyric acid secretion, neurotransmission 2
                  negative regulation of synaptic transmission, GABAergic 8
                  positive regulation of synaptic transmission, GABAergic 16
                  regulation of synaptic transmission, GABAergic + 36
Path 2
Term Annotations click to browse term
  biological_process 17883
    cellular process 16025
      cell communication 7127
        cell-cell signaling 1595
          synaptic signaling 866
            trans-synaptic signaling 857
              anterograde trans-synaptic signaling 848
                chemical synaptic transmission 848
                  synaptic transmission, GABAergic 58
                    gamma-aminobutyric acid secretion, neurotransmission 2
                    negative regulation of synaptic transmission, GABAergic 8
                    positive regulation of synaptic transmission, GABAergic 16
                    regulation of synaptic transmission, GABAergic + 36
paths to the root