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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synaptic transmission, glutamatergic
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Accession:GO:0051966 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.


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regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07002241.1 RGD:13792537
G AABR07061755.1 RGD:13792537
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:12050123
RGD:13792537
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:1624291
RGD:1600115
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2314643
G Dgki diacylglycerol kinase, iota JBrowse link 4 64,365,115 64,831,473 RGD:1624291
RGD:13792537
G Dgkz diacylglycerol kinase zeta JBrowse link 3 80,844,002 80,886,487 RGD:13792537
G Disc1 DISC1 scaffold protein JBrowse link 19 57,818,838 58,069,992 RGD:11344933
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:8553822
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:8553469
RGD:13792537
G Grm2 glutamate metabotropic receptor 2 JBrowse link 8 115,344,999 115,358,628 RGD:8553886
RGD:13792537
G Grm3 glutamate metabotropic receptor 3 JBrowse link 4 21,316,761 21,567,561 RGD:13792537
G Grm4 glutamate metabotropic receptor 4 JBrowse link 20 6,745,682 6,791,521 RGD:13792537
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:13792537
G Grm6 glutamate metabotropic receptor 6 JBrowse link 10 36,345,503 36,363,416 RGD:13792537
G Grm7 glutamate metabotropic receptor 7 JBrowse link 4 142,452,616 143,368,460 RGD:13792537
G Grm8 glutamate metabotropic receptor 8 JBrowse link 4 54,474,344 55,409,526 RGD:13792537
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:8553291
RGD:1600115
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:1624291
RGD:1600115
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Ophn1 oligophrenin 1 JBrowse link X 68,185,865 68,579,518 RGD:1624291
RGD:13792537
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1580676
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
RGD:1600115
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:1624291
RGD:1600115
G Syt1 synaptotagmin 1 JBrowse link 7 50,084,063 50,638,996 RGD:1624291
RGD:1600115
G Tprg1l tumor protein p63 regulated 1-like JBrowse link 5 171,456,299 171,459,488 RGD:13792549
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:1642787
negative regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:1625231
G Atad1 ATPase family, AAA domain containing 1 JBrowse link 1 251,234,702 251,386,996 RGD:1624291
RGD:1600115
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
RGD:13792537
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:13792537
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1642466
RGD:1624291
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:8554693
RGD:1624291
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:8554693
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:1626454
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:1624386
G LOC500460 similar to olfactory receptor Olr841 JBrowse link 5 64,614,755 64,615,714 RGD:13792537
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:1642508
G Olr1257 olfactory receptor 1257 JBrowse link 8 42,429,993 42,430,928 RGD:13792537
G Olr1320 olfactory receptor 1320 JBrowse link 8 43,628,182 43,629,120 RGD:13792537
G Olr533 olfactory receptor 533 JBrowse link 3 74,574,075 74,575,010 RGD:13792537
G Olr841 olfactory receptor 841 JBrowse link 5 64,621,407 64,622,359 RGD:13792537
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:6482754
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:10413844
positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtnbp1 dystrobrevin binding protein 1 JBrowse link 17 20,090,136 20,182,332 RGD:11251758
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 JBrowse link 13 44,578,208 44,649,876 RGD:1624291
RGD:1600115
positive regulation of glutamate secretion, neurotransmission term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:13513901
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:12904030
positive regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325299
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1625231
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:2311325
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:1600115
RGD:1624291
G Ccr2 C-C motif chemokine receptor 2 RGD:1600115
RGD:1624291
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:1624291
RGD:1600115
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1581898
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:2301558
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 JBrowse link 8 1,548,145 2,045,874 RGD:8554601
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:9681553
G Iqsec2 IQ motif and Sec7 domain ArfGEF 2 JBrowse link X 22,212,137 22,293,810 RGD:11049506
G LOC103690160 SH3 and multiple ankyrin repeat domains protein 2-like JBrowse link 1 215,208,591 215,246,638 RGD:13792537
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:5508750
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8554760
RGD:8554379
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Nps neuropeptide S JBrowse link 1 207,508,414 207,512,195 RGD:1624291
RGD:13792537
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1600115
RGD:1624291
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:5144124
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:1626130
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:2304108
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300272
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:8553497
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1600115
RGD:1624291
G Ror2 receptor tyrosine kinase-like orphan receptor 2 JBrowse link 17 11,953,552 12,134,386 RGD:11537351
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:13792537
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:1624291
RGD:13792537
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1600115
RGD:13792537
RGD:1624291
RGD:7349315
G Tnr tenascin R JBrowse link 13 77,602,249 77,678,385 RGD:1624291
RGD:1600115
G Tshz3 teashirt zinc finger homeobox 3 JBrowse link 1 92,703,180 92,775,020 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    regulation of biological process 12516
      regulation of signaling 3470
        regulation of trans-synaptic signaling 653
          modulation of chemical synaptic transmission 652
            regulation of synaptic transmission, glutamatergic 81
              negative regulation of synaptic transmission, glutamatergic + 17
              positive regulation of synaptic transmission, glutamatergic + 34
              regulation of glutamate secretion, neurotransmission + 4
Path 2
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      cell communication 7446
        cell-cell signaling 1638
          synaptic signaling 891
            trans-synaptic signaling 867
              anterograde trans-synaptic signaling 858
                chemical synaptic transmission 858
                  modulation of chemical synaptic transmission 652
                    regulation of synaptic transmission, glutamatergic 81
                      negative regulation of synaptic transmission, glutamatergic + 17
                      positive regulation of synaptic transmission, glutamatergic + 34
                      regulation of glutamate secretion, neurotransmission + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.