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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of transmission of nerve impulse
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Accession:GO:0051969 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
Synonyms:exact_synonym: regulation of conduction of nerve impulse


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regulation of transmission of nerve impulse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen ISO RGD PMID:22198171 RGD:8549468 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO RGD PMID:23525979 RGD:12907567 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Ghsr growth hormone secretagogue receptor ISO RGD PMID:23525979 RGD:12907567 NCBI chrNW_004936593:268,736...273,623 JBrowse link
G Tymp thymidine phosphorylase ISO (PMID:9924029) CAFA PMID:9924029 NCBI chrNW_004936629:315,609...320,356 JBrowse link
negative regulation of neuronal action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr35 G protein-coupled receptor 35 ISO PMID:17940199 UniProt PMID:17940199 RGD:11541107 NCBI chrNW_004936745:993,375...994,292 JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 ISO RGD PMID:18048010 RGD:10412022 NCBI chrNW_004936704:1,667,387...1,689,337 JBrowse link
negative regulation of transmission of nerve impulse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:16304841 RGD:2300377 NCBI chrNW_004936545:1,788,995...1,795,842 JBrowse link
G Glra1 glycine receptor alpha 1 ISO (PMID:11973623) UniProtKB PMID:11973623 NCBI chrNW_004936515:10,816,712...10,896,958 JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO orexin A/Hcrt1 polypeptide; sympathetic nerves of brown adipose tissue RGD PMID:15746258 RGD:1600996 NCBI chrNW_004936490:17,007,001...17,008,363 JBrowse link
G Mtnr1b melatonin receptor 1B ISO RGD PMID:15082174 RGD:9588675 NCBI chrNW_004936674:1,703,814...1,713,860 JBrowse link
positive regulation of neuronal action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta ISO (PMID:25456120) ParkinsonsUK-UCL PMID:25456120 NCBI chrNW_004936580:4,715,869...4,720,752 JBrowse link
G Oprk1 opioid receptor kappa 1 ISO RGD PMID:7895938, PMID:18036588 RGD:11554210, RGD:11556242 NCBI chrNW_004936496:280,593...305,900 JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO RGD PMID:19889854 RGD:9835339 NCBI chrNW_004936698:650,225...746,593 JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 ISO RGD PMID:25126967 RGD:9850100 NCBI chrNW_004936509:2,722,279...3,006,436 JBrowse link
positive regulation of transmission of nerve impulse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide ISO (PMID:11711504) HGNC PMID:11711504 NCBI chrNW_004936549:4,717,337...4,719,523 JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO (MGI:MGI:3610896|PMID:12606764) CACAO PMID:12606764 MGI:MGI:3610896 NCBI chrNW_004936471:36,408,471...36,425,571 JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO orexin B/Hcrt2 polypeptide; sympathetic nerves of brown adipose tissue RGD PMID:15746258 RGD:1600996 NCBI chrNW_004936490:17,007,001...17,008,363 JBrowse link
G Itga2 integrin subunit alpha 2 ISO RGD PMID:15501602 RGD:2307400 NCBI chrNW_004936480:14,320,292...14,417,828 JBrowse link
G Mtnr1b melatonin receptor 1B ISO RGD PMID:22171046 RGD:9588665 NCBI chrNW_004936674:1,703,814...1,713,860 JBrowse link
G Tnr tenascin R ISO (MGI:MGI:1337730|PMID:10341229) MGI PMID:10341229 MGI:MGI:1337730 NCBI chrNW_004936481:12,586,460...12,972,348 JBrowse link
regulation of neuronal action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf12 fibroblast growth factor 12 ISO (PMID:27164707) UniProtKB PMID:27164707 NCBI chrNW_004936711:1,873,030...2,378,028 JBrowse link
G Fmr1 FMRP translational regulator 1 ISO (PMID:25561520) UniProtKB PMID:25561520 NCBI chrNW_004936513:1,290,038...1,327,850 JBrowse link
G Ifng interferon gamma ISO RGD PMID:7715823 RGD:8158038 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Mtnr1b melatonin receptor 1B ISO RGD PMID:21094224 RGD:9588677 NCBI chrNW_004936674:1,703,814...1,713,860 JBrowse link
G Trpa1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:20205719 RGD:10043789 NCBI chrNW_004936648:1,094,460...1,141,394 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11998
    regulation of biological process 8336
      regulation of signaling 2892
        regulation of transmission of nerve impulse 22
          modulation of transmission of nerve impulse in other organism 0
          negative regulation of transmission of nerve impulse + 6
          positive regulation of transmission of nerve impulse + 10
          regulation of neuronal action potential + 11
Path 2
Term Annotations click to browse term
  biological_process 11998
    biological regulation 8793
      regulation of biological process 8336
        regulation of multicellular organismal process 2574
          regulation of system process 591
            regulation of nervous system process 169
              regulation of transmission of nerve impulse 22
                modulation of transmission of nerve impulse in other organism 0
                negative regulation of transmission of nerve impulse + 6
                positive regulation of transmission of nerve impulse + 10
                regulation of neuronal action potential + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.