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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of transmission of nerve impulse
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Accession:GO:0051970 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
Synonyms:exact_synonym: down regulation of transmission of nerve impulse;   downregulation of transmission of nerve impulse;   negative regulation of conduction of nerve impulse
 narrow_synonym: inhibition of transmission of nerve impulse


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negative regulation of transmission of nerve impulse term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVP arginine vasopressin ISO RGD PMID:16304841 RGD:2300377 NCBI chr20:3,169,094...3,172,900 JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO RGD PMID:16304841 RGD:2300377 NCBI chr12:25,793,633...25,803,026
Ensembl chr12:26,065,882...26,075,972
JBrowse link
G GLRA1 glycine receptor alpha 1 ISO (PMID:11973623) UniProtKB PMID:11973623 NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567
JBrowse link
G HCRT hypocretin neuropeptide precursor ISO orexin A/Hcrt1 polypeptide; sympathetic nerves of brown adipose tissue RGD PMID:15746258 RGD:1600996 NCBI chr17:15,130,581...15,132,024
Ensembl chr17:15,353,203...15,354,594
JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:15082174 RGD:9588675 NCBI chr11:87,996,805...88,009,865
Ensembl chr11:91,491,822...91,504,652
JBrowse link
negative regulation of neuronal action potential term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR35 G protein-coupled receptor 35 ISO PMID:17940199 UniProt PMID:17940199 RGD:11541107 NCBI chr2B:127,853,660...127,887,204
Ensembl chr2B:246,680,998...246,692,090
JBrowse link
G KCNC4 potassium voltage-gated channel subfamily C member 4 ISO RGD PMID:18048010 RGD:10412022 NCBI chr 1:112,860,887...112,884,687
Ensembl chr 1:127,458,968...127,480,182
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    signaling 4292
      negative regulation of signaling 1287
        negative regulation of transmission of nerve impulse 7
          negative regulation of neuronal action potential 2
Path 2
Term Annotations click to browse term
  biological_process 12566
    biological regulation 9172
      regulation of biological process 8675
        regulation of multicellular organismal process 2678
          regulation of system process 614
            regulation of nervous system process 180
              regulation of transmission of nerve impulse 23
                negative regulation of transmission of nerve impulse 7
                  negative regulation of neuronal action potential 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.