ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of chromosome segregation
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Accession:GO:0051985 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
Synonyms:exact_synonym: down regulation of chromosome segregation;   downregulation of chromosome segregation
 narrow_synonym: inhibition of chromosome segregation


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negative regulation of chromosome segregation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chtf18 chromosome transmission fidelity factor 18 JBrowse link 10 15,090,762 15,098,825 RGD:1624291
deactivation of mitotic spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdt1 chromatin licensing and DNA replication factor 1 JBrowse link 19 55,381,565 55,386,511 RGD:1624291
RGD:1600115
meiotic spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ttk Ttk protein kinase JBrowse link 8 91,368,065 91,405,995 RGD:1624291
RGD:13792537
mitotic spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
RGD:1600115
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
RGD:1600115
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:1600115
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:1600115
RGD:1624291
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:13792537
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:13792537
G Bub3 BUB3 mitotic checkpoint protein JBrowse link 1 203,526,853 203,537,459 RGD:13792537
G Cenpe centromere protein E JBrowse link 2 240,395,974 240,454,785 RGD:1624291
G Ik IK cytokine JBrowse link 18 29,587,901 29,602,705 RGD:1624291
RGD:1600115
G Khdc3 KH domain containing 3, subcortical maternal complex member JBrowse link 8 79,781,941 79,783,845 RGD:1624291
G Klhl22 kelch-like family member 22 JBrowse link 11 87,646,489 87,718,808 RGD:1600115
RGD:13792537
RGD:1624291
G Mad1l1 mitotic arrest deficient 1 like 1 JBrowse link 12 16,410,083 16,721,232 RGD:13792537
RGD:1624291
G Mad2l1 mitotic arrest deficient 2 like 1 JBrowse link 4 97,530,993 97,543,179 RGD:1624291
RGD:13792537
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1600115
RGD:1624291
G Psmg2 proteasome assembly chaperone 2 JBrowse link 18 63,394,991 63,420,491 RGD:1624291
RGD:1600115
G Spdl1 spindle apparatus coiled-coil protein 1 JBrowse link 10 19,628,070 19,652,914 RGD:1600115
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Tex14 testis expressed 14, intercellular bridge forming factor JBrowse link 10 74,724,070 74,849,172 RGD:1600115
RGD:13792537
RGD:1624291
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1600115
RGD:1624291
RGD:13792537
G Trip13 thyroid hormone receptor interactor 13 JBrowse link 1 31,967,980 32,012,923 RGD:1624291
RGD:1600115
G Ttk Ttk protein kinase JBrowse link 8 91,368,065 91,405,995 RGD:1624291
RGD:13792537
G Zfp207 zinc finger protein 207 JBrowse link 10 67,762,970 67,784,854 RGD:1624291
RGD:13792537
G Zw10 zw10 kinetochore protein JBrowse link 8 53,365,881 53,390,742 RGD:13792537
negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit JBrowse link X 156,863,655 156,868,950 RGD:1624291
RGD:1600115
negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:1624291
RGD:1600115
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
RGD:1600115
negative regulation of metaphase/anaphase transition of meiotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk1 leucine-rich repeat kinase 1 JBrowse link 1 127,166,866 127,301,053 RGD:13792537
G Mos MOS proto-oncogene, serine/threonine kinase JBrowse link 5 16,746,085 16,747,392 RGD:1600115
RGD:1624291
RGD:13792537
negative regulation of mitotic metaphase/anaphase transition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fbxo5 F-box protein 5 JBrowse link 1 42,461,277 42,467,646 RGD:1600115
RGD:1624291
G Rad21 RAD21 cohesin complex component JBrowse link 7 91,511,755 91,538,673 RGD:1624291
RGD:1600115
negative regulation of mitotic sister chromatid separation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pttg1 PTTG1 regulator of sister chromatid separation, securin JBrowse link 10 29,014,332 29,026,088 RGD:13792537
negative regulation of sister chromatid cohesion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Recql4 RecQ like helicase 4 JBrowse link 7 117,765,892 117,773,128 RGD:1624291
G Wapl WAPL cohesin release factor JBrowse link 16 11,029,325 11,108,867 RGD:1624291
RGD:1600115
positive regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:1600115
RGD:1624291
G Gen1 GEN1 Holliday junction 5' flap endonuclease JBrowse link 6 36,910,064 36,940,868 RGD:1624291
RGD:1600115
G Mad2l1 mitotic arrest deficient 2 like 1 JBrowse link 4 97,530,993 97,543,179 RGD:1624291
RGD:1600115
G Ndc80 NDC80 kinetochore complex component JBrowse link 9 119,837,857 119,871,435 RGD:1624291
RGD:1600115
G Pcid2 PCI domain containing 2 JBrowse link 16 81,757,582 81,783,047 RGD:1624291
RGD:1600115
G Tpr translocated promoter region, nuclear basket protein JBrowse link 13 67,611,685 67,672,833 RGD:1600115
RGD:1624291
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:1624291
RGD:1600115
regulation of mitotic cell cycle spindle assembly checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anapc15 anaphase promoting complex subunit 15 JBrowse link 1 166,981,738 166,985,363 RGD:1624291
RGD:13792537
RGD:1600115
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1624291
RGD:1600115
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:1600115
G Lcmt1 leucine carboxyl methyltransferase 1 JBrowse link 1 193,335,629 193,391,620 RGD:1624291
RGD:1600115
G Usp44 ubiquitin specific peptidase 44 JBrowse link 7 34,714,293 34,759,352 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17926
    cellular process 16077
      chromosome segregation 309
        negative regulation of chromosome segregation 46
          negative regulation of attachment of spindle microtubules to kinetochore + 0
          negative regulation of chromosome separation + 40
          negative regulation of meiotic spindle elongation 0
          negative regulation of sister chromatid segregation + 43
Path 2
Term Annotations click to browse term
  biological_process 17926
    biological regulation 12622
      regulation of biological process 11964
        regulation of cellular process 11300
          negative regulation of cellular process 4787
            negative regulation of chromosome segregation 46
              negative regulation of attachment of spindle microtubules to kinetochore + 0
              negative regulation of chromosome separation + 40
              negative regulation of meiotic spindle elongation 0
              negative regulation of sister chromatid segregation + 43
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.