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ONTOLOGY REPORT - ANNOTATIONS


Term:carboxylic ester hydrolase activity
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Accession:GO:0052689 term browser browse the term
Definition:Catalysis of the hydrolysis of a carboxylic ester bond.
Synonyms:exact_synonym: carboxyesterase activity;   carboxyl ester hydrolase activity;   carboxylate esterase activity;   carboxylesterase activity;   carboxylic acid esterase activity;   carboxylic esterase activity
 narrow_synonym: alpha-carboxylesterase activity;   cocaine esterase activity;   procaine esterase activity;   triacetin esterase;   vitamin A esterase
 related_synonym: Ali-esterase activity;   B-esterase activity;   esterase A;   esterase B;   nonspecific carboxylesterase activity;   serine esterase activity
 alt_id: GO:0004091;   GO:0004302;   GO:0004759;   GO:0016789
 xref: EC:3.1.1;   EC:3.1.1.1;   KEGG_REACTION:R00630;   MetaCyc:CARBOXYLESTERASE-RXN;   UM-BBD_reactionID:r1025;   reactome:R-HSA-5693691 "CES1 trimer.CES2 hydrolyse COCN to BEG";   reactome:R-HSA-8937442 "CES3 hydrolyses CHEST to CHOL and LCFA(-)";   reactome:R-HSA-9619024 "CES1trimer hydrolyses ACEI pro-drugs to ACEIs"


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carboxylic ester hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034648.1 RGD:1600115
G AABR07042565.1 RGD:13792537
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 15 32,888,233 32,906,861 RGD:13792537
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase JBrowse link 8 130,973,222 131,001,448 RGD:13792537
G Acot1 acyl-CoA thioesterase 1 JBrowse link 6 107,485,088 107,493,082 RGD:1600115
G Acot12 acyl-CoA thioesterase 12 JBrowse link 2 20,857,056 20,901,656 RGD:1600115
G Acot2 acyl-CoA thioesterase 2 JBrowse link 6 107,460,596 107,468,324 RGD:1600115
G Acot7 acyl-CoA thioesterase 7 JBrowse link 5 169,357,582 169,450,215 RGD:1600115
G Acot8 acyl-CoA thioesterase 8 JBrowse link 3 161,260,837 161,272,495 RGD:1600115
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:1600115
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:724678
G Ces1a carboxylesterase 1A JBrowse link 19 15,339,152 15,366,079 RGD:13792537
G Ces1c carboxylesterase 1C JBrowse link 19 15,294,524 15,335,005 RGD:632749
RGD:13792537
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:632439
RGD:13792537
RGD:1624291
RGD:70683
G Ces1e carboxylesterase 1E RGD:632434
RGD:13792537
G Ces1f carboxylesterase 1F JBrowse link 19 15,081,117 15,126,629 RGD:13792537
G Ces2 carboxylesterase 2 JBrowse link 1 282,694,908 282,702,176 RGD:13792537
G Ces2a carboxylesterase 2A JBrowse link 19 59,110 64,378 RGD:724430
RGD:13792537
G Ces2c carboxylesterase 2C JBrowse link 1 282,640,752 282,648,319 RGD:13792537
G Ces2e carboxylesterase 2E JBrowse link 19 85,679 100,386 RGD:13792537
G Ces2g carboxylesterase 2G JBrowse link 19 37,025,379 37,034,611 RGD:13792537
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:1624291
RGD:13792537
G Ces2i carboxylesterase 2I JBrowse link 1 282,569,926 282,575,202 RGD:13792537
G Ces2j carboxylesterase 2J JBrowse link 19 487,723 495,140 RGD:13792537
G Ces4a carboxylesterase 4A JBrowse link 19 37,090,018 37,111,448 RGD:13792537
G Ces5a carboxylesterase 5A JBrowse link 19 12,097,529 12,136,579 RGD:13792537
G Cesl1 carboxylesterase-like 1 RGD:13792537
G Esd esterase D JBrowse link 15 56,756,848 56,776,348 RGD:1600115
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308774
G Liph lipase H JBrowse link 11 82,680,167 82,732,145 RGD:1600115
G Lipi lipase I JBrowse link 11 13,960,246 13,999,869 RGD:1600115
G LOC100365112 carboxylesterase-like RGD:13792537
G LOC108348093 acylcarnitine hydrolase-like JBrowse link 1 282,671,390 282,691,028 RGD:13792537
G LOC679149 similar to carboxylesterase 2 (intestine, liver) JBrowse link 19 433 6,319 RGD:13792537
G Lypla1 lysophospholipase 1 JBrowse link 5 14,559,333 14,588,447 RGD:13792537
G Lypla2 lysophospholipase 2 JBrowse link 5 154,315,033 154,319,629 RGD:13792537
G Lyplal1 lysophospholipase-like 1 JBrowse link 13 104,049,263 104,080,680 RGD:13792537
G Notum NOTUM, palmitoleoyl-protein carboxylesterase JBrowse link 10 109,832,977 109,840,661 RGD:13792537
G Pnliprp1 pancreatic lipase-related protein 1 JBrowse link 1 279,867,034 279,882,663 RGD:1600115
G Pnpla7 patatin-like phospholipase domain containing 7 JBrowse link 3 2,182,191 2,261,890 RGD:1299462
1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pnliprp2 pancreatic lipase related protein 2 JBrowse link 1 279,896,973 279,927,600 RGD:1600115
1-acyl-2-lysophosphatidylserine acylhydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:1600115
1-alkyl-2-acetylglycerophosphocholine esterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aspg asparaginase JBrowse link 6 136,682,279 136,701,673 RGD:1299414
G Pafah1b2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 JBrowse link 8 50,256,969 50,310,043 RGD:1600115
G Pafah1b3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 JBrowse link 1 82,163,733 82,166,259 RGD:1600115
G Pafah2 platelet-activating factor acetylhydrolase 2 JBrowse link 5 152,606,850 152,635,956 RGD:1540381
RGD:13792537
RGD:1600115
G Pla2g7 phospholipase A2 group VII JBrowse link 9 19,935,754 19,978,013 RGD:1624291
RGD:13792537
3,4-dihydrocoumarin hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pon3 paraoxonase 3 JBrowse link 4 30,311,981 30,338,679 RGD:1303961
6-phosphogluconolactonase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) JBrowse link 5 166,994,683 167,030,441 RGD:1624291
G Pgls 6-phosphogluconolactonase JBrowse link 16 20,020,444 20,025,930 RGD:2311501
RGD:13792537
RGD:1600115
RGD:1624291
acetylcholinesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:724758
RGD:1600115
RGD:1624291
RGD:2301213
RGD:2301207
RGD:2301205
RGD:2301204
RGD:2301203
RGD:2301199
RGD:2301197
RGD:2301195
RGD:2301187
RGD:1580870
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:1624291
acetylesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase JBrowse link 1 140,998,240 141,087,405 RGD:1624291
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:1600115
acyl-L-homoserine-lactone lactonohydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:1600115
G Pon2 paraoxonase 2 JBrowse link 4 30,344,705 30,380,119 RGD:1600115
G Pon3 paraoxonase 3 JBrowse link 4 30,311,981 30,338,679 RGD:1600115
acylcarnitine hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ces2c carboxylesterase 2C JBrowse link 1 282,640,752 282,648,319 RGD:1624291
acylglycerol lipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd1 abhydrolase domain containing 1 JBrowse link 6 26,787,807 26,792,795 RGD:13792537
G Abhd12 abhydrolase domain containing 12, lysophospholipase JBrowse link 3 146,630,298 146,690,375 RGD:1600115
RGD:1624291
G Abhd16a abhydrolase domain containing 16A, phospholipase JBrowse link 20 5,080,070 5,094,935 RGD:1624291
RGD:1600115
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase JBrowse link 1 140,998,240 141,087,405 RGD:1624291
RGD:13792537
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:13792537
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase JBrowse link 15 18,647,903 18,695,133 RGD:1624291
RGD:13792537
RGD:1600115
G Faah fatty acid amide hydrolase JBrowse link 5 134,852,899 134,872,095 RGD:1624291
RGD:14397564
G Faahl fatty-acid amide hydrolase-like JBrowse link 5 134,330,204 134,349,400 RGD:1624291
RGD:14397564
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308779
G Lipe lipase E, hormone sensitive type JBrowse link 1 82,248,031 82,266,727 RGD:1581872
G Mgll monoglyceride lipase JBrowse link 4 120,671,436 120,773,458 RGD:1600115
RGD:13792537
RGD:1624291
RGD:14397564
G Pnliprp2 pancreatic lipase related protein 2 JBrowse link 1 279,896,973 279,927,600 RGD:1624291
RGD:1600115
acyloxyacyl hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aoah acyloxyacyl hydrolase JBrowse link 17 45,872,414 46,115,026 RGD:1624291
Ala-tRNA(Thr) hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtd2 D-aminoacyl-tRNA deacylase 2 JBrowse link 6 72,781,229 72,786,835 RGD:1624291
all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpe65 retinoid isomerohydrolase RPE65 JBrowse link 2 266,141,581 266,169,197 RGD:6893661
RGD:1624291
RGD:13792537
RGD:1600115
all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rpe65 retinoid isomerohydrolase RPE65 JBrowse link 2 266,141,581 266,169,197 RGD:1600115
RGD:1624291
aminoacyl-tRNA editing activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aars alanyl-tRNA synthetase JBrowse link 19 43,193,264 43,215,281 RGD:1624291
RGD:13792537
RGD:1600115
G Aars2 alanyl-tRNA synthetase 2, mitochondrial JBrowse link 9 17,869,301 17,881,762 RGD:13792537
G Aarsd1 alanyl-tRNA synthetase domain containing 1 JBrowse link 10 89,317,974 89,331,078 RGD:1624291
G Dtd1 D-aminoacyl-tRNA deacylase 1 JBrowse link 3 138,770,573 138,931,544 RGD:13792537
G Dtd2 D-aminoacyl-tRNA deacylase 2 JBrowse link 6 72,781,229 72,786,835 RGD:13792537
G Iars1 isoleucyl-tRNA synthetase 1 JBrowse link 17 15,356,016 15,402,680 RGD:1600115
G Iars2 isoleucyl-tRNA synthetase 2, mitochondrial JBrowse link 13 103,229,868 103,265,019 RGD:1600115
G Lars1 leucyl-tRNA synthetase 1 JBrowse link 18 36,524,013 36,579,471 RGD:1600115
G Lars2 leucyl-tRNA synthetase 2, mitochondrial JBrowse link 8 132,441,277 132,537,176 RGD:1600115
G LOC103690033 isoleucine--tRNA ligase, cytoplasmic-like JBrowse link 17 14,541,646 14,562,733 RGD:1600115
G Prorsd1 prolyl-tRNA synthetase associated domain containing 1 JBrowse link 14 113,938,061 113,940,330 RGD:1600115
G Tars2 threonyl-tRNA synthetase 2, mitochondrial JBrowse link 2 197,861,071 197,881,347 RGD:1624291
RGD:1600115
G Vars1 valyl-tRNA synthetase 1 JBrowse link 20 4,993,539 5,008,259 RGD:1600115
G Vars2 valyl-tRNA synthetase 2, mitochondrial JBrowse link 20 3,588,462 3,599,514 RGD:1600115
aminoacyl-tRNA hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mrpl58 mitochondrial ribosomal protein L58 JBrowse link 10 103,956,019 103,962,515 RGD:1624291
G Ptrh1 peptidyl-tRNA hydrolase 1 homolog JBrowse link 3 11,811,303 11,817,007 RGD:13792537
G Ptrh2 peptidyl-tRNA hydrolase 2 JBrowse link 10 74,002,151 74,012,182 RGD:1624291
RGD:13792537
G Ptrhd1 peptidyl-tRNA hydrolase domain containing 1 JBrowse link 6 28,663,602 28,666,987 RGD:1600115
arylesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apmap adipocyte plasma membrane associated protein JBrowse link 3 146,376,828 146,407,259 RGD:1600115
RGD:1624291
G Car1 carbonic anhydrase 1 JBrowse link 2 88,185,204 88,227,486 RGD:1624291
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:1624291
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:1624291
RGD:13792537
RGD:1600115
G Pon2 paraoxonase 2 JBrowse link 4 30,344,705 30,380,119 RGD:13792537
G Pon3 paraoxonase 3 JBrowse link 4 30,311,981 30,338,679 RGD:1303961
RGD:13792537
RGD:1624291
calcium-dependent phospholipase A2 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102546467 HERV-H LTR-associating protein 1-like JBrowse link 7 106,442,364 106,485,324 RGD:13792537
G Oc90 otoconin 90 JBrowse link 7 106,615,859 106,697,089 RGD:13792537
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:2303763
RGD:1624291
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:2303763
RGD:13792537
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:69933
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:13792537
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:13792537
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1642483
RGD:13792537
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1624291
RGD:13792537
G Pla2g4c phospholipase A2 group IVC JBrowse link 1 75,440,035 75,481,995 RGD:13792537
G Pla2g4d phospholipase A2 group IVD JBrowse link 3 112,040,827 112,061,847 RGD:1624291
RGD:13792537
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:13792537
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
RGD:13792537
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:61698
RGD:13792537
calcium-independent phospholipase A2 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pla2g15 phospholipase A2, group XV JBrowse link 19 38,129,666 38,146,958 RGD:1304489
RGD:1624291
G Pla2g4c phospholipase A2 group IVC JBrowse link 1 75,440,035 75,481,995 RGD:1624291
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:729507
G Pla2g7 phospholipase A2 group VII JBrowse link 9 19,935,754 19,978,013 RGD:1624291
G Pnpla8 patatin-like phospholipase domain containing 8 JBrowse link 6 64,224,870 64,288,465 RGD:1624291
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:1624291
cholinesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:1624291
RGD:1600115
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:1599453
RGD:1624291
RGD:2301195
RGD:2301187
G Chka choline kinase alpha JBrowse link 1 219,076,618 219,126,221 RGD:1624291
D-tyrosyl-tRNA(Tyr) deacylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dtd1 D-aminoacyl-tRNA deacylase 1 JBrowse link 3 138,770,573 138,931,544 RGD:13792537
G Dtd2 D-aminoacyl-tRNA deacylase 2 JBrowse link 6 72,781,229 72,786,835 RGD:1624291
RGD:13792537
fatty-acyl-ethyl-ester synthase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:1600115
galactolipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pnliprp2 pancreatic lipase related protein 2 JBrowse link 1 279,896,973 279,927,600 RGD:2303162
RGD:13792537
RGD:1600115
RGD:1624291
gluconolactonase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590200
RGD:13792537
RGD:1624291
RGD:1600115
hormone-sensitive lipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase JBrowse link 1 140,998,240 141,087,405 RGD:1624291
G Lipe lipase E, hormone sensitive type JBrowse link 1 82,248,031 82,266,727 RGD:1600115
lipoprotein lipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:1600115
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:70246
RGD:1624291
RGD:10047183
RGD:1580532
lysophospholipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd12 abhydrolase domain containing 12, lysophospholipase JBrowse link 3 146,630,298 146,690,375 RGD:1600115
RGD:1624291
G Abhd16a abhydrolase domain containing 16A, phospholipase JBrowse link 20 5,080,070 5,094,935 RGD:1624291
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B JBrowse link 15 32,888,233 32,906,861 RGD:1624291
G Alkbh5 alkB homolog 5, RNA demethylase JBrowse link 10 46,906,314 46,927,759 RGD:1624291
G Aspg asparaginase JBrowse link 6 136,682,279 136,701,673 RGD:1299414
RGD:14695081
RGD:2303783
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:2313552
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 7 94,479,931 94,563,086 RGD:8553522
RGD:15090854
RGD:1624291
RGD:1600115
RGD:13792537
G Gde1 glycerophosphodiester phosphodiesterase 1 JBrowse link 1 188,367,550 188,407,125 RGD:1624291
RGD:1600115
G Gdpd1 glycerophosphodiester phosphodiesterase domain containing 1 JBrowse link 10 74,334,972 74,376,332 RGD:1600115
RGD:13792537
RGD:1624291
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 JBrowse link 1 198,199,032 198,209,178 RGD:1624291
RGD:13792537
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308772
G Lypla1 lysophospholipase 1 JBrowse link 5 14,559,333 14,588,447 RGD:633195
RGD:1624291
G Lypla2 lysophospholipase 2 JBrowse link 5 154,315,033 154,319,629 RGD:1624291
RGD:1600115
G Pla2g15 phospholipase A2, group XV JBrowse link 19 38,129,666 38,146,958 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1600115
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1624291
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:6903950
RGD:13792537
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:1624291
RGD:13792537
G Pnpla7 patatin-like phospholipase domain containing 7 JBrowse link 3 2,182,191 2,261,890 RGD:1624291
RGD:13792537
methyl indole-3-acetate esterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ces1c carboxylesterase 1C JBrowse link 19 15,294,524 15,335,005 RGD:1600115
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:1600115
G Ces1e carboxylesterase 1E RGD:1600115
G Ces1f carboxylesterase 1F JBrowse link 19 15,081,117 15,126,629 RGD:1600115
G Ces5a carboxylesterase 5A JBrowse link 19 12,097,529 12,136,579 RGD:1600115
G Cesl1 carboxylesterase-like 1 RGD:1600115
mycophenolic acid acyl-glucuronide esterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd10 abhydrolase domain containing 10, depalmitoylase JBrowse link 11 60,053,719 60,068,142 RGD:1600115
G LOC103693563 mycophenolic acid acyl-glucuronide esterase, mitochondrial JBrowse link 11 57,485,649 57,500,476 RGD:1600115
palmitoleyl hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notum NOTUM, palmitoleoyl-protein carboxylesterase JBrowse link 10 109,832,977 109,840,661 RGD:1624291
RGD:13792537
phosphatidylinositol deacylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pgap1 post-GPI attachment to proteins inositol deacylase 1 JBrowse link 9 61,066,170 61,134,963 RGD:13792537
phosphatidylserine 1-acylhydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:1600115
phospholipase A1 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:1624291
RGD:13792537
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:2308772
G Lipg lipase G, endothelial type JBrowse link 18 70,903,528 70,924,434 RGD:1624291
G Pla1a phospholipase A1 member A JBrowse link 11 64,882,024 64,919,714 RGD:1624291
G Plaat1 phospholipase A and acyltransferase 1 JBrowse link 11 75,125,951 75,145,868 RGD:1624291
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:12790655
RGD:1624291
G Plaat5 phospholipase A and acyltransferase 5 JBrowse link 1 222,907,159 222,937,643 RGD:1624291
phospholipase A2 activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:1624291
RGD:13792537
G Lcat lecithin cholesterol acyltransferase JBrowse link 19 37,913,333 37,916,799 RGD:729077
G LOC102546467 HERV-H LTR-associating protein 1-like JBrowse link 7 106,442,364 106,485,324 RGD:13792537
G Oc90 otoconin 90 JBrowse link 7 106,615,859 106,697,089 RGD:13792537
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1582547
RGD:1600115
G Pla2g12a phospholipase A2, group XIIA JBrowse link 2 235,311,664 235,327,972 RGD:1624291
RGD:13792537
G Pla2g12b phospholipase A2, group XIIB JBrowse link 20 28,989,440 29,007,967 RGD:1600115
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:1302902
RGD:1624291
RGD:8553780
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:628361
RGD:13792537
RGD:1624291
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:1600115
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:13792537
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:1624291
RGD:13792537
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:1600115
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:633563
RGD:13792537
RGD:1624291
RGD:1600115
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1624291
RGD:13792537
G Pla2g4c phospholipase A2 group IVC JBrowse link 1 75,440,035 75,481,995 RGD:13792537
G Pla2g4d phospholipase A2 group IVD JBrowse link 3 112,040,827 112,061,847 RGD:1624291
RGD:13792537
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:1624291
RGD:13792537
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1624291
RGD:13792537
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:1624291
RGD:13792537
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:1600115
G Plaat1 phospholipase A and acyltransferase 1 JBrowse link 11 75,125,951 75,145,868 RGD:1624291
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:12790655
RGD:1624291
G Plaat5 phospholipase A and acyltransferase 5 JBrowse link 1 222,907,159 222,937,643 RGD:1624291
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:6903950
RGD:13792537
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:1624291
G Proca1 protein interacting with cyclin A1 JBrowse link 10 65,454,451 65,469,491 RGD:1600115
phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102546467 HERV-H LTR-associating protein 1-like JBrowse link 7 106,442,364 106,485,324 RGD:1600115
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1600115
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:1600115
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:1600115
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:1600115
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:1600115
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:1600115
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1600115
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1600115
G Pla2g4d phospholipase A2 group IVD JBrowse link 3 112,040,827 112,061,847 RGD:1600115
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:1600115
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1600115
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:1600115
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:1600115
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:1600115
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:1600115
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:1600115
phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102546467 HERV-H LTR-associating protein 1-like JBrowse link 7 106,442,364 106,485,324 RGD:1600115
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1600115
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:1600115
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:1600115
G Pla2g2c phospholipase A2, group IIC JBrowse link 5 157,163,672 157,187,654 RGD:1600115
G Pla2g2d phospholipase A2, group IID JBrowse link 5 157,222,636 157,228,795 RGD:1600115
G Pla2g2f phospholipase A2, group IIF JBrowse link 5 157,192,047 157,217,265 RGD:1600115
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1600115
G Pla2g4b phospholipase A2 group IVB JBrowse link 3 111,824,919 111,833,526 RGD:1600115
G Pla2g4d phospholipase A2 group IVD JBrowse link 3 112,040,827 112,061,847 RGD:1600115
G Pla2g4e phospholipase A2, group IVE JBrowse link 3 111,952,396 112,018,470 RGD:1600115
G Pla2g4f phospholipase A2, group IVF JBrowse link 3 112,068,617 112,083,978 RGD:1600115
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:1600115
G Pla2g6 phospholipase A2 group VI JBrowse link 7 120,519,479 120,559,716 RGD:1600115
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:1600115
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:1600115
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:1600115
protein C-terminal methylesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppme1 protein phosphatase methylesterase 1 JBrowse link 1 165,335,242 165,382,216 RGD:1624291
protein methylesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppme1 protein phosphatase methylesterase 1 JBrowse link 1 165,335,242 165,382,216 RGD:13792537
retinyl-palmitate esterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:2313555
G Plb1 phospholipase B1 JBrowse link 6 25,375,699 25,507,108 RGD:6903951
RGD:13792537
G Pnpla4 patatin like phospholipase domain containing 4 JBrowse link X 45,519,406 45,522,988 RGD:1624291
Ser-tRNA(Ala) hydrolase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aars alanyl-tRNA synthetase JBrowse link 19 43,193,264 43,215,281 RGD:1600115
RGD:1624291
G Aarsd1 alanyl-tRNA synthetase domain containing 1 JBrowse link 10 89,317,974 89,331,078 RGD:1624291
RGD:13792537
short-chain carboxylesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07010747.1 RGD:13792537
G Aadac arylacetamide deacetylase JBrowse link 2 150,146,234 150,157,480 RGD:13792537
G Aadacl2 arylacetamide deacetylase-like 2 JBrowse link 2 150,344,307 150,365,033 RGD:13792537
G Aadacl3 arylacetamide deacetylase-like 3 JBrowse link 5 162,323,373 162,332,014 RGD:13792537
G Aadacl4 arylacetamide deacetylase-like 4 JBrowse link 5 162,676,109 162,688,907 RGD:13792537
G Abhd1 abhydrolase domain containing 1 JBrowse link 6 26,787,807 26,792,795 RGD:13792537
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase JBrowse link 1 140,998,240 141,087,405 RGD:13792537
G Abhd3 abhydrolase domain containing 3, phospholipase JBrowse link 18 1,892,413 1,946,840 RGD:13792537
G AC111231.1 RGD:13792537
G LOC100910567 arylacetamide deacetylase-like 2-like JBrowse link 2 150,106,180 150,127,280 RGD:13792537
G LOC691196 similar to arylacetamide deacetylase JBrowse link 5 166,293,476 166,335,979 RGD:13792537
G Nceh1 neutral cholesterol ester hydrolase 1 JBrowse link 2 112,868,834 112,932,622 RGD:13792537
G RGD1308878 similar to arylacetamide deacetylase JBrowse link 5 162,506,652 162,516,264 RGD:13792537
G RGD1559622 similar to hypothetical protein C130079G13 JBrowse link 2 149,714,565 149,754,734 RGD:13792537
G RGD1559644 similar to novel protein similar to esterases JBrowse link 5 162,727,638 162,751,145 RGD:13792537
G RGD1560324 similar to hypothetical protein C130079G13 JBrowse link 2 149,899,527 150,023,909 RGD:13792537
G RGD1561998 similar to hypothetical protein C130079G13 JBrowse link 2 149,843,238 149,871,729 RGD:13792537
G RGD1563334 similar to novel protein similar to esterases JBrowse link 5 162,593,460 162,602,329 RGD:13792537
sialate O-acetylesterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Siae sialic acid acetylesterase JBrowse link 8 40,078,269 40,113,514 RGD:1600115
RGD:1624291
sterol esterase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:728247
RGD:13792537
G Ces1a carboxylesterase 1A JBrowse link 19 15,339,152 15,366,079 RGD:13792537
G Ces1c carboxylesterase 1C JBrowse link 19 15,294,524 15,335,005 RGD:13792537
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:1600115
RGD:13792537
RGD:1624291
G Ces1e carboxylesterase 1E RGD:13792537
G Ces1f carboxylesterase 1F JBrowse link 19 15,081,117 15,126,629 RGD:13792537
G Ces4a carboxylesterase 4A JBrowse link 19 37,090,018 37,111,448 RGD:13792537
G Ces5a carboxylesterase 5A JBrowse link 19 12,097,529 12,136,579 RGD:13792537
G Cesl1 carboxylesterase-like 1 RGD:13792537
G Lipa lipase A, lysosomal acid type JBrowse link 1 252,816,536 252,959,348 RGD:1626385
RGD:13792537
RGD:1624291
RGD:1600115
G Lipo1 lipase, member O1 JBrowse link 1 252,102,233 252,117,030 RGD:13792537
triglyceride lipase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadac arylacetamide deacetylase JBrowse link 2 150,146,234 150,157,480 RGD:1600115
RGD:13792537
RGD:1624291
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase JBrowse link 8 130,973,222 131,001,448 RGD:1624291
RGD:1600115
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:2313555
RGD:13792537
G Ces1a carboxylesterase 1A JBrowse link 19 15,339,152 15,366,079 RGD:13792537
G Ces1c carboxylesterase 1C JBrowse link 19 15,294,524 15,335,005 RGD:13792537
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:1600115
RGD:13792537
RGD:1624291
G Ces1e carboxylesterase 1E RGD:13792537
G Ces1f carboxylesterase 1F JBrowse link 19 15,081,117 15,126,629 RGD:13792537
G Ces4a carboxylesterase 4A JBrowse link 19 37,090,018 37,111,448 RGD:13792537
G Ces5a carboxylesterase 5A JBrowse link 19 12,097,529 12,136,579 RGD:13792537
G Cesl1 carboxylesterase-like 1 RGD:13792537
G Ddhd2 DDHD domain containing 2 JBrowse link 16 71,090,096 71,120,713 RGD:1624291
RGD:13792537
G Lipc lipase C, hepatic type JBrowse link 8 77,272,582 77,398,485 RGD:1580511
RGD:1624291
RGD:1600115
RGD:1600649
RGD:1600640
G Lipe lipase E, hormone sensitive type JBrowse link 1 82,248,031 82,266,727 RGD:1624291
G Lipf lipase F, gastric type JBrowse link 1 252,284,464 252,302,811 RGD:1600115
G LOC100911615 patatin-like phospholipase domain-containing protein 2-like JBrowse link 1 213,997,721 214,002,811 RGD:1600115
RGD:13792537
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:1624291
G Pnlip pancreatic lipase JBrowse link 1 279,798,187 279,811,372 RGD:2303166
RGD:13792537
RGD:1624291
RGD:1600115
G Pnliprp1 pancreatic lipase-related protein 1 JBrowse link 1 279,867,034 279,882,663 RGD:1600115
G Pnliprp2 pancreatic lipase related protein 2 JBrowse link 1 279,896,973 279,927,600 RGD:2303166
RGD:13792537
RGD:1624291
RGD:1600115
G Pnpla1 patatin-like phospholipase domain containing 1 JBrowse link 20 6,101,061 6,143,762 RGD:13792537
G Pnpla2 patatin-like phospholipase domain containing 2 JBrowse link 1 214,434,638 214,439,720 RGD:1624291
RGD:13792537
RGD:1600115
G Pnpla3 patatin-like phospholipase domain containing 3 JBrowse link 7 125,034,760 125,056,165 RGD:1624291
RGD:13792537
G Pnpla4 patatin like phospholipase domain containing 4 JBrowse link X 45,519,406 45,522,988 RGD:1624291
RGD:13792537
G Pnpla5 patatin-like phospholipase domain containing 5 JBrowse link 7 124,988,524 124,999,137 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19528
    catalytic activity 6039
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 781
          carboxylic ester hydrolase activity 156
            1,2-diacylglycerol acylhydrolase activity 0
            1,3-diacylglycerol acylhydrolase activity 0
            1,4-lactonase activity 0
            1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity 0
            1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity 1
            1-acyl-2-lysophosphatidylserine acylhydrolase activity 1
            1-alkyl-2-acetylglycerophosphocholine esterase activity 5
            1-oxa-2-oxocycloheptane lactonase activity 0
            11-cis-retinyl-palmitate hydrolase activity 0
            2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity 0
            2-pyrone-4,6-dicarboxylate lactonase activity 0
            3,4-dihydrocoumarin hydrolase activity 1
            3-oxoadipate enol-lactonase activity 0
            4-O-methyl-glucuronoyl methylesterase activity 0
            4-methyloxaloacetate esterase activity 0
            4-pyridoxolactonase activity 0
            4-sulfomuconolactone hydrolase activity 0
            5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity 0
            6-acetylglucose deacetylase activity 0
            6-phosphogluconolactonase activity 2
            D-arabinonolactonase activity 0
            L-arabinonolactonase activity 0
            L-ascorbate 6-phosphate lactonase activity 0
            L-rhamnono-1,4-lactonase activity 0
            N-acetylgalactosaminoglycan deacetylase activity 0
            Ser(Gly)-tRNA(Ala) hydrolase activity 0
            Ser-tRNA(Thr) hydrolase activity 0
            acetoxybutynylbithiophene deacetylase activity 0
            acetylajmaline esterase activity 0
            acetylalkylglycerol acetylhydrolase activity 0
            acetylsalicylate deacetylase activity 0
            acetylxylan esterase activity 0
            aclacinomycin A methylesterase activity 0
            aclacinomycin T methylesterase activity 0
            actinomycin lactonase activity 0
            acylcarnitine hydrolase activity 1
            acylglycerol lipase activity 12
            acyloxyacyl hydrolase activity 1
            all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 1
            all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity 1
            all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity 0
            alpha-amino-acid esterase activity 0
            aminoacyl-tRNA editing activity + 14
            aminoacyl-tRNA hydrolase activity 4
            arylesterase activity 6
            bis(2-ethylhexyl)phthalate esterase activity 0
            brefeldin A esterase activity 0
            butyrolactone hydrolase activity 0
            carboxymethylenebutenolidase activity 0
            cephalosporin-C deacetylase activity 0
            cetraxate benzylesterase activity 0
            chitooligosaccharide deacetylase activity 0
            chlorogenate hydrolase activity 0
            chlorophyllase activity 0
            cholinesterase activity + 3
            cutinase activity 0
            deoxylimonate A-ring-lactonase activity 0
            dihydrocoumarin hydrolase activity 0
            diphthine methylesterase activity 0
            endosulfan lactone lactonase activity 0
            epsilon-rhodomycinone methylesterase activity 0
            fatty-acyl-ethyl-ester synthase activity 1
            feruloyl esterase activity 0
            fusarinine-C ornithinesterase activity 0
            galactolipase activity 1
            gluconolactonase activity 1
            heparan sulfate N-deacetylase activity 0
            hormone-sensitive lipase activity 2
            hydroxybutyrate-dimer hydrolase activity 0
            juvenile-hormone esterase activity 0
            lactonohydrolase activity + 3
            limonin-D-ring-lactonase activity 0
            lysophospholipase activity 20
            methyl indole-3-acetate esterase activity 6
            methyl jasmonate esterase activity 0
            methyl salicylate esterase activity 0
            methylumbelliferyl-acetate deacetylase activity 0
            mycophenolic acid acyl-glucuronide esterase activity 2
            orsellinate-depside hydrolase activity 0
            palmitoleyl hydrolase activity 1
            pectin acetylesterase activity 0
            pectinesterase activity 0
            pheophoridase activity 0
            pheophytinase activity 0
            pheophytinase b activity 0
            phorbol-diester hydrolase activity 0
            phosphatidyl phospholipase B activity 0
            phosphatidylinositol deacylase activity 1
            phosphatidylserine 1-acylhydrolase activity 1
            phospholipase A1 activity 7
            phospholipase A2 activity + 31
            phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) 17
            phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) 17
            pimelyl-[acyl-carrier protein] methyl ester esterase activity 0
            poly(3-hydroxybutyrate) depolymerase activity 0
            poly(3-hydroxyoctanoate) depolymerase activity 0
            polyneuridine-aldehyde esterase activity 0
            protein methylesterase activity + 1
            retinyl-palmitate esterase activity 3
            short-chain carboxylesterase activity + 20
            sinapine esterase activity 0
            steroid-lactonase activity 0
            sterol esterase activity 11
            sulfolactone hydrolase activity 0
            tannase activity 0
            trans-permethrin hydrolase activity 0
            triacetate-lactonase activity 0
            triglyceride lipase activity + 26
            tropinesterase activity 0
            uronolactonase activity 0
            vinylacetate caboxylester hydrolase activity 0
            wax-ester hydrolase activity 0
            xylono-1,4-lactonase activity 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.