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ONTOLOGY REPORT - ANNOTATIONS


Term:xenobiotic glucuronidation
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Accession:GO:0052697 term browser browse the term
Definition:The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion.
Synonyms:narrow_synonym: phase II metabolism


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xenobiotic glucuronidation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RGD1559459 similar to Expressed sequence AI788959 JBrowse link 14 22,932,454 22,955,663 RGD:1624291
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:1624291
RGD:13792537
RGD:10769352
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:1624291
RGD:13792537
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 JBrowse link 9 95,274,707 95,302,822 RGD:13792537
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 JBrowse link 9 95,256,628 95,302,822 RGD:13792537
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 9 95,241,609 95,302,822 RGD:13792537
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C JBrowse link 9 95,233,957 95,302,822 RGD:13792537
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:1624291
RGD:13792537
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      cellular metabolic process 10782
        xenobiotic metabolic process 103
          xenobiotic glucuronidation 9
Path 2
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      small molecule metabolic process 1834
        organic acid metabolic process 1068
          oxoacid metabolic process 1041
            carboxylic acid metabolic process 993
              monocarboxylic acid metabolic process 652
                uronic acid metabolic process 15
                  glucuronate metabolic process 15
                    cellular glucuronidation 14
                      xenobiotic glucuronidation 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.