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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac myofibril assembly
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Accession:GO:0055003 term browser browse the term
Definition:The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
Synonyms:exact_synonym: cardiac myofibril development;   cardiac myofibril morphogenesis
 related_synonym: heart myofibril assembly


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cardiac myofibril assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:1624291
RGD:1600115
G Csrp3 cysteine and glycine rich protein 3 JBrowse link 1 104,147,205 104,166,389 RGD:1624291
RGD:1600115
G Fhod3 formin homology 2 domain containing 3 JBrowse link 18 16,650,786 17,332,209 RGD:1624291
RGD:1600115
G Myh10 myosin heavy chain 10 JBrowse link 10 55,274,910 55,406,738 RGD:1624291
RGD:1600115
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:1624291
RGD:1600115
G Mylk3 myosin light chain kinase 3 JBrowse link 19 27,388,163 27,442,451 RGD:8554371
RGD:13792537
G Myom1 myomesin 1 JBrowse link 9 119,353,840 119,469,196 RGD:13792537
G Myom2 myomesin 2 JBrowse link 16 79,587,136 79,672,871 RGD:13792537
G Myom3 myomesin 3 JBrowse link 5 154,109,293 154,159,943 RGD:13792537
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:1600115
RGD:1624291
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
RGD:1600115
G Tcap titin-cap JBrowse link 10 86,337,705 86,338,414 RGD:1624291
G Ttn titin JBrowse link 3 63,565,160 63,837,815 RGD:1624291
cardiac muscle thin filament assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neb nebulin JBrowse link 3 37,658,081 37,855,843 RGD:13792537
G Nebl nebulette JBrowse link 17 84,141,014 84,247,038 RGD:1600115
RGD:13792537
RGD:1624291
G Nrap nebulin-related anchoring protein JBrowse link 1 277,104,519 277,181,397 RGD:13792537
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
ventricular cardiac myofibril assembly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mef2a myocyte enhancer factor 2a JBrowse link 1 128,207,715 128,341,681 RGD:1600115
RGD:1624291
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    developmental process 6637
      anatomical structure formation involved in morphogenesis 1187
        cellular component assembly involved in morphogenesis 122
          myofibril assembly 71
            cardiac myofibril assembly 21
              atrial cardiac myofibril assembly 0
              cardiac muscle myosin thick filament assembly 0
              cardiac muscle thin filament assembly 3
              negative regulation of cardiac myofibril assembly 1
              positive regulation of cardiac myofibril assembly 0
              regulation of cardiac myofibril assembly + 1
              ventricular cardiac myofibril assembly 3
Path 2
Term Annotations click to browse term
  biological_process 19312
    developmental process 6637
      anatomical structure development 6101
        multicellular organism development 5570
          system development 5099
            animal organ development 3898
              heart development 684
                cardiocyte differentiation 183
                  cardiac muscle cell differentiation 146
                    cardiac muscle cell development 102
                      cardiac myofibril assembly 21
                        atrial cardiac myofibril assembly 0
                        cardiac muscle myosin thick filament assembly 0
                        cardiac muscle thin filament assembly 3
                        negative regulation of cardiac myofibril assembly 1
                        positive regulation of cardiac myofibril assembly 0
                        regulation of cardiac myofibril assembly + 1
                        ventricular cardiac myofibril assembly 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.