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ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac muscle tissue growth
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Accession:GO:0055017 term browser browse the term
Definition:The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
Synonyms:exact_synonym: heart muscle growth


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cardiac muscle tissue growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccm2l CCM2 like scaffold protein JBrowse link 3 148,541,404 148,557,464 RGD:1624291
G Heg1 heart development protein with EGF-like domains 1 JBrowse link 11 70,234,248 70,322,966 RGD:1624291
cardiac muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid2 AT-rich interaction domain 2 JBrowse link 7 137,680,564 137,798,329 RGD:1624291
G Bmp10 bone morphogenetic protein 10 JBrowse link 4 119,224,906 119,230,534 RGD:1600115
RGD:1624291
G Dipk2a divergent protein kinase domain 2A JBrowse link 8 102,140,713 102,159,828 RGD:1624291
RGD:13792537
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Foxc2 forkhead box C2 JBrowse link 19 53,044,379 53,047,081 RGD:1624291
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha JBrowse link 10 97,940,705 97,959,199 RGD:1624291
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1624291
RGD:1600115
G Rxrb retinoid X receptor beta JBrowse link 20 3,822,673 3,829,138 RGD:1624291
G Smad1 SMAD family member 1 JBrowse link 19 32,182,942 32,248,694 RGD:1624291
RGD:1600115
G Tenm4 teneurin transmembrane protein 4 JBrowse link 1 161,183,858 161,885,094 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
cardiac muscle tissue growth involved in heart morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 2 218,654,406 218,658,761 RGD:1624291
RGD:1600115
cell growth involved in cardiac muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:1624291
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:1624291
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:5129173
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:6903878
G Akap13 A-kinase anchoring protein 13 JBrowse link 1 137,089,558 137,315,272 RGD:2312638
G Camk2d calcium/calmodulin-dependent protein kinase II delta JBrowse link 2 230,900,907 231,132,207 RGD:6907064
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:5131529
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:13792737
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:7495831
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:1580138
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:5132877
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:1580138
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:1580138
G Pdlim5 PDZ and LIM domain 5 JBrowse link 2 247,815,214 247,989,198 RGD:10054083
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:7775063
G Sorbs2 sorbin and SH3 domain containing 2 JBrowse link 16 49,626,205 49,820,223 RGD:10054083
negative regulation of cardiac muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:13464260
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:13210532
G Cxadr CXADR, Ig-like cell adhesion molecule JBrowse link 11 16,826,269 16,873,564 RGD:1624291
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:7207421
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:1624291
G Jarid2 jumonji and AT-rich interaction domain containing 2 JBrowse link 17 20,183,440 20,365,219 RGD:11522645
G Kcnk2 potassium two pore domain channel subfamily K member 2 JBrowse link 13 107,690,111 107,886,476 RGD:9831164
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:1624291
G Meis1 Meis homeobox 1 JBrowse link 14 103,182,178 103,321,809 RGD:12911005
G Mir1 microRNA 1 JBrowse link 18 2,054,933 2,055,019 RGD:1624291
G Nog noggin JBrowse link 10 76,811,759 76,813,386 RGD:1624291
RGD:1600115
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Rbp4 retinol binding protein 4 JBrowse link 1 256,806,476 256,813,678 RGD:1624291
G Ripk1 receptor interacting serine/threonine kinase 1 JBrowse link 17 31,537,580 31,569,904 RGD:1624291
G Sav1 salvador family WW domain containing protein 1 JBrowse link 6 92,376,470 92,398,678 RGD:1624291
G Tbx5 T-box transcription factor 5 JBrowse link 12 42,059,688 42,148,226 RGD:1600115
RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1601597
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:1624291
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav3 caveolin 3 JBrowse link 4 144,382,945 144,398,919 RGD:6784534
G Ctdp1 CTD phosphatase subunit 1 JBrowse link 18 76,922,913 76,985,095 RGD:9686371
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:11561912
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:10449133
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1624291
G Mir451a microRNA 451a JBrowse link 10 65,291,204 65,291,275 RGD:11558015
G Pak1 p21 (RAC1) activated kinase 1 JBrowse link 1 162,768,156 162,883,356 RGD:11533929
G Pi16 peptidase inhibitor 16 JBrowse link 20 6,923,176 6,932,786 RGD:1624291
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:5687133
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:13524577
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:7207376
G Tomm70 translocase of outer mitochondrial membrane 70 JBrowse link 11 45,477,053 45,511,409 RGD:13464131
G Yy1 YY1 transcription factor JBrowse link 6 132,702,443 132,726,848 RGD:9588273
positive regulation of cardiac muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp10 bone morphogenetic protein 10 JBrowse link 4 119,224,906 119,230,534 RGD:1624291
RGD:1600115
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:2301353
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:2301353
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:8655650
RGD:1624291
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
RGD:10402047
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:1624291
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:1624291
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:1624291
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:13800890
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:1624291
RGD:1600115
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Ncam1 neural cell adhesion molecule 1 JBrowse link 8 53,836,797 54,134,881 RGD:2325979
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Tbx2 T-box transcription factor 2 JBrowse link 10 73,278,932 73,290,764 RGD:1624291
G Tbx20 T-box transcription factor 20 JBrowse link 8 25,849,394 25,904,570 RGD:1624291
G Tbx5 T-box transcription factor 5 JBrowse link 12 42,059,688 42,148,226 RGD:1624291
RGD:1600115
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:1624291
G Wnt2 Wnt family member 2 JBrowse link 4 45,286,845 45,332,899 RGD:1624291
G Yap1 Yes1 associated transcriptional regulator JBrowse link 8 6,133,014 6,204,240 RGD:1624291
G Zfpm2 zinc finger protein, multitype 2 JBrowse link 7 79,471,277 79,964,405 RGD:1624291
RGD:1600115
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129139
G Akap6 A-kinase anchoring protein 6 JBrowse link 6 73,553,111 73,991,992 RGD:6902940
RGD:2312613
G Ccn4 cellular communication network factor 4 JBrowse link 7 107,695,227 107,723,759 RGD:5129173
G Ddx39b DExD-box helicase 39B JBrowse link 20 4,806,103 4,818,600 RGD:10401141
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:2312280
G Fdps farnesyl diphosphate synthase JBrowse link 2 188,403,595 188,413,219 RGD:2316294
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:11041632
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10040977
RGD:10040978
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:7174736
G Parp2 poly (ADP-ribose) polymerase 2 JBrowse link 15 27,739,416 27,749,650 RGD:13514044
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 8 21,669,236 21,680,615 RGD:8693424
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:13514043
G Slc25a4 solute carrier family 25 member 4 JBrowse link 16 49,266,903 49,270,698 RGD:9681466
G Trip10 thyroid hormone receptor interactor 10 JBrowse link 9 9,689,214 9,702,353 RGD:11535145
post-embryonic cardiac muscle cell growth involved in heart morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:9586060
regulation of cardiac muscle cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
G Fgf20 fibroblast growth factor 20 JBrowse link 16 55,152,748 55,159,352 RGD:1624291
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:1624291
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:1624291
G Mir133a1 microRNA 133a-1 JBrowse link 18 2,052,478 2,052,564 RGD:1624291
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col14a1 collagen type XIV alpha 1 chain JBrowse link 7 95,054,877 95,274,073 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      developmental growth 819
        cardiac muscle tissue growth 108
          cardiac muscle cell proliferation + 60
          cardiac muscle tissue growth involved in heart morphogenesis + 2
          negative regulation of cardiac muscle tissue growth + 31
          physiological cardiac muscle hypertrophy + 46
          positive regulation of cardiac muscle tissue growth + 44
          regulation of cardiac muscle tissue growth + 79
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            circulatory system development 1201
              heart development 682
                heart growth 117
                  cardiac muscle tissue growth 108
                    cardiac muscle cell proliferation + 60
                    cardiac muscle tissue growth involved in heart morphogenesis + 2
                    negative regulation of cardiac muscle tissue growth + 31
                    physiological cardiac muscle hypertrophy + 46
                    positive regulation of cardiac muscle tissue growth + 44
                    regulation of cardiac muscle tissue growth + 79
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.