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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cardiac muscle tissue growth
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Accession:GO:0055022 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.
Synonyms:exact_synonym: down regulation of cardiac muscle growth;   downregulation of cardiac muscle growth
 narrow_synonym: inhibition of cardiac muscle growth
 related_synonym: negative regulation of heart muscle growth


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negative regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IMP PMID:28948298 BHF-UCL PMID:28948298 RGD:13464260 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IMP PMID:26240138 BHF-UCL PMID:26240138 RGD:13210532 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule ISO MGI:3711226 (MGI:3709954|PMID:16543498) RGD PMID:16543498 MGI:3709954 NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562
JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:19377854 RGD:7207421 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Hdac2 histone deacetylase 2 ISO MGI:3712002 (MGI:3711360|PMID:17322895) RGD PMID:17322895 MGI:3711360 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 IDA
IMP
PMID:26298346 BHF-UCL PMID:26298346, PMID:26298346 RGD:11522645, RGD:11522645 NCBI chr17:20,183,440...20,365,219
Ensembl chr17:20,184,245...20,364,714
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IMP RGD PMID:24705172 RGD:9831164 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO MGI:3609429 (MGI:5288131|PMID:21768366) RGD PMID:21768366 MGI:5288131 NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
JBrowse link
G Meis1 Meis homeobox 1 IMP PMID:28111633 BHF-UCL PMID:28111633 RGD:12911005 NCBI chr14:103,182,178...103,321,809
Ensembl chr14:103,181,281...103,321,270
JBrowse link
G Mir1 microRNA 1 ISO (MGI:5575655|PMID:17397913) RGD PMID:17397913 MGI:5575655 NCBI chr18:2,054,933...2,055,019 JBrowse link
G Nog noggin IEA
ISO
ISS
GO_REF:0000107
(MGI:3783944|PMID:17218603)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17218603 GO_REF:0000024, GO_REF:0000107, MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Pten phosphatase and tensin homolog ISO RNAcentral:URS000006FDD4_10090|RNAcentral:URS000013D17D_10090 (MGI:5584062|PMID:23575307) RGD PMID:23575307 MGI:5584062 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Rbp4 retinol binding protein 4 ISO (MGI:2655947|PMID:12663486) RGD PMID:12663486 MGI:2655947 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO (MGI:6271967|PMID:30321469) RGD PMID:30321469 MGI:6271967 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Sav1 salvador family WW domain containing protein 1 ISO MGI:2654594|MGI:4430538 (MGI:4948149|PMID:21512031) RGD PMID:21512031 MGI:4948149 NCBI chr 6:92,376,470...92,398,678
Ensembl chr 6:92,376,093...92,398,525
JBrowse link
G Tbx5 T-box transcription factor 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:11161571)
Ensembl
UniProt
RGD
PMID:11161571 GO_REF:0000024, GO_REF:0000107 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IMP RGD PMID:15537505 RGD:1601597 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tp73 tumor protein p73 ISO (PMID:18634800) RGD PMID:18634800 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Vgll4 vestigial-like family member 4 ISO (MGI:6120600|PMID:27720608) RGD PMID:27720608 MGI:6120600 NCBI chr 4:146,778,556...146,890,063
Ensembl chr 4:146,779,276...146,839,397
JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:76,922,913...76,985,095
Ensembl chr18:76,922,934...76,984,203
JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO (MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:4829580 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Pi16 peptidase inhibitor 16 ISO (MGI:3810223|PMID:17909105) RGD PMID:17909105 MGI:3810223 NCBI chr20:6,923,176...6,932,786
Ensembl chr20:6,923,489...6,932,786
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961
JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046
JBrowse link
G Zfp418 zinc finger protein 418 ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr 1:69,615,413...69,629,997
Ensembl chr 1:69,615,434...69,629,913
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    growth 1094
      developmental growth 819
        cardiac muscle tissue growth 111
          negative regulation of cardiac muscle tissue growth 33
            negative regulation of cardiac muscle cell proliferation 19
            negative regulation of cell growth involved in cardiac muscle cell development 14
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            circulatory system development 1225
              heart development 687
                heart growth 121
                  regulation of heart growth 88
                    regulation of cardiac muscle tissue growth 81
                      negative regulation of cardiac muscle tissue growth 33
                        negative regulation of cardiac muscle cell proliferation 19
                        negative regulation of cell growth involved in cardiac muscle cell development 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.