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ONTOLOGY REPORT - ANNOTATIONS


Term:pharyngeal system development
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Accession:GO:0060037 term browser browse the term
Definition:The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.


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pharyngeal system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 IEA
ISO
GO_REF:0000107
MGI:2386570|MGI:2651395 (MGI:3703113|PMID:17078885)
Ensembl
RGD
PMID:17078885 GO_REF:0000107, MGI:3703113 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Bmp5 bone morphogenetic protein 5 ISO UniProtKB:P23359 (MGI:1332253|PMID:10079236) RGD PMID:10079236 MGI:1332253 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO UniProtKB:P49003 (MGI:1332253|PMID:10079236) RGD PMID:10079236 MGI:1332253 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Ece1 endothelin converting enzyme 1 IEA
ISO
GO_REF:0000107
MGI:2158947 (MGI:2675516|PMID:12950083)
Ensembl
RGD
PMID:12950083 GO_REF:0000107, MGI:2675516 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO MGI:102780|MGI:98493|MGI:99604 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO MGI:102780|MGI:109344|MGI:98493 (MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:5002778 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Gata3 GATA binding protein 3 ISS
ISO
GO_REF:0000024
(MGI:3832106|PMID:18955134)
UniProt
RGD
PMID:18955134 GO_REF:0000024, MGI:3832106 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Isl1 ISL LIM homeobox 1 ISO UniProtKB:Q02248 (MGI:3829137|PMID:17519333) RGD PMID:17519333 MGI:3829137 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Nkx2-5 NK2 homeobox 5 IEA
ISO
GO_REF:0000107
MGI:97351 (MGI:2135851|PMID:11390666)
Ensembl
RGD
PMID:11390666 GO_REF:0000107, MGI:2135851 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Nkx2-6 NK2 homeobox 6 ISO MGI:97350 (MGI:2135851|PMID:11390666), (PMID:9486544), (PMID:9545560), (PMID:9621431) RGD PMID:9486544, PMID:9545560, PMID:9621431, PMID:11390666 MGI:2135851 NCBI chr15:51,034,620...51,038,715
Ensembl chr15:51,034,620...51,038,704
JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO (PMID:9621431) RGD PMID:9621431 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Plxna2 plexin A2 ISO (PMID:19666519) RGD PMID:19666519 NCBI chr13:113,373,569...113,570,774
Ensembl chr13:113,373,578...113,571,648
JBrowse link
G Ptch1 patched 1 ISO (PMID:8681379), (PMID:8981943) RGD PMID:8681379, PMID:8981943 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Ripply3 ripply transcriptional repressor 3 ISO (MGI:4879036|PMID:21177346) RGD PMID:21177346 MGI:4879036 NCBI chr11:34,557,679...34,565,776
Ensembl chr11:34,557,679...34,565,776
JBrowse link
G Six1 SIX homeobox 1 ISO MGI:109344|MGI:98493|MGI:99604 (MGI:3624596|PMID:16530750), (MGI:5002778|PMID:21364285) RGD PMID:16530750, PMID:21364285 MGI:3624596, MGI:5002778 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
G Six4 SIX homeobox 4 ISO (MGI:3624596|PMID:16530750) RGD PMID:16530750 MGI:3624596 NCBI chr 6:95,984,868...95,999,709
Ensembl chr 6:95,984,868...95,998,529
JBrowse link
G Tbx1 T-box transcription factor 1 ISO
ISS
(PMID:14585638)
MGI:102780|MGI:109344|MGI:3046793|MGI:99604 (MGI:3763333|PMID:16141220), (MGI:4879036|PMID:21177346), (MGI:5002778|PMID:21364285)
GO_REF:0000024
RGD
UniProt
PMID:14585638, PMID:16141220, PMID:21177346, PMID:21364285 GO_REF:0000024, MGI:3763333, MGI:4879036, MGI:5002778 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO MGI:2386570|MGI:2388050 (MGI:3703113|PMID:17078885) RGD PMID:17078885 MGI:3703113 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
pharyngeal arch artery morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrf4 adhesion G protein-coupled receptor F4 ISO MGI:2182928 (MGI:5919853|PMID:28806758) RGD PMID:28806758 MGI:5919853 NCBI chr 9:20,951,249...20,982,493
Ensembl chr 9:20,951,260...20,982,487
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 IEA
ISO
GO_REF:0000107
MGI:1925499 (MGI:5919853|PMID:28806758)
Ensembl
RGD
PMID:28806758 GO_REF:0000107, MGI:5919853 NCBI chr 9:20,091,121...20,195,706
Ensembl chr 9:20,091,099...20,195,566
JBrowse link
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(MGI:3039210|PMID:15070745)
Ensembl
RGD
PMID:15070745 GO_REF:0000107, MGI:3039210 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT ISO (MGI:2429424|PMID:12441304)
(MGI:3851675|PMID:19409885)
RGD PMID:12441304, PMID:19409885 MGI:2429424, MGI:3851675 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Folr1 folate receptor alpha ISO (MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:3721767 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Hes1 hes family bHLH transcription factor 1 IEA
ISO
GO_REF:0000107
(MGI:4453944|PMID:20122914)
Ensembl
RGD
PMID:20122914 GO_REF:0000107, MGI:4453944 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Nog noggin IEA
ISO
GO_REF:0000107
(MGI:3783944|PMID:17218603)
Ensembl
RGD
PMID:17218603 GO_REF:0000107, MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO MGI:3605892 (MGI:5469230|PMID:23319608) RGD PMID:23319608 MGI:5469230 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:3609313|PMID:11390347) RGD PMID:11390347 MGI:3609313 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    multicellular organismal process 9047
      multicellular organism development 5743
        system development 5279
          pharyngeal system development 28
            pharyngeal arch artery morphogenesis 10
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          embryo development 1307
            embryo development ending in birth or egg hatching 861
              chordate embryonic development 845
                pharyngeal system development 28
                  pharyngeal arch artery morphogenesis 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.