Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:cardiac muscle cell proliferation
go back to main search page
Accession:GO:0060038 term browser browse the term
Definition:The expansion of a cardiac muscle cell population by cell division.
Synonyms:exact_synonym: cardiac myocyte proliferation;   heart muscle cell proliferation
 related_synonym: cardiomyocyte proliferation


show annotations for term's descendants           Sort by:
 
cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid2 AT-rich interaction domain 2 ISO (MGI:5649178|PMID:25299188) MGI PMID:25299188 MGI:5649178 NCBI chrNW_004936512:4,020,303...4,199,390 JBrowse link
G Bmp10 bone morphogenetic protein 10 ISO (MGI:3040529|PMID:15073151) UniProt PMID:15073151 MGI:3040529 NCBI chrNW_004936491:13,180,086...13,186,004 JBrowse link
G Dipk2a divergent protein kinase domain 2A ISO (PMID:23784961) UniProtKB PMID:23784961 NCBI chrNW_004936519:10,966,822...10,988,311 JBrowse link
G Foxc2 forkhead box C2 ISO (MGI:3701735|PMID:16839542) MGI PMID:16839542 MGI:3701735 NCBI chrNW_004936641:2,236,224...2,238,501 JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO (MGI:5429684|PMID:17350578) MGI PMID:17350578 MGI:5429684 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:5298073|PMID:21311046) BHF-UCL PMID:21311046 MGI:5298073 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha ISO (MGI:3821563|PMID:18316483) MGI PMID:18316483 MGI:3821563 NCBI chrNW_004936541:7,845,876...7,863,677 JBrowse link
G Rxra retinoid X receptor alpha ISO (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chrNW_004936669:2,735,111...2,763,060 JBrowse link
G Rxrb retinoid X receptor beta ISO (MGI:1101382|PMID:9428411) MGI PMID:9428411 MGI:1101382 NCBI chrNW_004936476:25,655,164...25,662,369 JBrowse link
G Smad1 SMAD family member 1 ISO (MGI:5429684|PMID:17350578) MGI PMID:17350578 MGI:5429684 NCBI chrNW_004936535:3,582,512...3,626,312 JBrowse link
G Tenm4 teneurin transmembrane protein 4 ISO (MGI:5429684|PMID:17350578) MGI PMID:17350578 MGI:5429684 NCBI chrNW_004936498:7,145,510...7,868,792 JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO (PMID:15896309) UniProtKB PMID:15896309 NCBI chrNW_004936628:310,720...394,002 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chrNW_004936537:7,154,125...7,340,218 JBrowse link
negative regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO PMID:28948298 BHF-UCL PMID:28948298 RGD:13464260 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO PMID:26240138 BHF-UCL PMID:26240138 RGD:13210532 NCBI chrNW_004936560:6,353,901...6,356,749 JBrowse link
G Cxadr CXADR Ig-like cell adhesion molecule ISO (MGI:3709954|PMID:16543498) MGI PMID:16543498 MGI:3709954 NCBI chrNW_004936505:9,971,393...10,032,238 JBrowse link
G Hdac2 histone deacetylase 2 ISO (MGI:3711360|PMID:17322895) MGI PMID:17322895 MGI:3711360 NCBI chrNW_004936679:2,448,676...2,474,641 JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 ISO PMID:26298346 BHF-UCL PMID:26298346 RGD:11522645 NCBI chrNW_004936552:1,566,382...1,786,837 JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:24705172 RGD:9831164 NCBI chrNW_004936628:3,155,261...3,284,375 JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO (MGI:5288131|PMID:21768366) MGI PMID:21768366 MGI:5288131 NCBI chrNW_004936629:542,143...549,861 JBrowse link
G Meis1 Meis homeobox 1 ISO PMID:28111633 BHF-UCL PMID:28111633 RGD:12911005 NCBI chrNW_004936491:11,079,574...11,216,451 JBrowse link
G Nog noggin ISO (MGI:3783944|PMID:17218603) BHF-UCL PMID:17218603 MGI:3783944 NCBI chrNW_004936490:6,262,651...6,264,069 JBrowse link
G Pten phosphatase and tensin homolog ISO (MGI:5584062|PMID:23575307) BHF-UCL PMID:23575307 MGI:5584062 NCBI chrNW_004936735:1,252,414...1,338,318 JBrowse link
G Rbp4 retinol binding protein 4 ISO (MGI:2655947|PMID:12663486) BHF-UCL PMID:12663486 MGI:2655947 NCBI chrNW_004936601:1,401,215...1,410,195 JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO (MGI:6271967|PMID:30321469) ARUK-UCL PMID:30321469 MGI:6271967 NCBI chrNW_004936534:9,326,307...9,361,943 JBrowse link
G Sav1 salvador family WW domain containing protein 1 ISO (MGI:4948149|PMID:21512031) MGI PMID:21512031 MGI:4948149 NCBI chrNW_004936495:14,955,234...14,977,720 JBrowse link
G Tbx5 T-box transcription factor 5 ISO (PMID:11161571) UniProtKB PMID:11161571 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO RGD PMID:15537505 RGD:1601597 NCBI chrNW_004936473:21,324,669...21,409,430 JBrowse link
G Tp73 tumor protein p73 ISO (PMID:18634800) MGI PMID:18634800 NCBI chrNW_004936737:171,894...211,464 JBrowse link
G Vgll4 vestigial like family member 4 ISO (MGI:6120600|PMID:27720608) UniProt PMID:27720608 MGI:6120600 NCBI chrNW_004936602:1,789,479...1,938,440 JBrowse link
positive regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chrNW_004936491:13,180,086...13,186,004 JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (MGI:3810850|PMID:18667463) BHF-UCL PMID:18667463 MGI:3810850 NCBI chrNW_004936804:52,435...115,289 JBrowse link
G Ccnb1 cyclin B1 ISO RGD PMID:15253691 RGD:2301353 NCBI chrNW_004936480:400,287...407,677 JBrowse link
G Cdk1 cyclin dependent kinase 1 ISO RGD PMID:15253691 RGD:2301353 NCBI chrNW_004936614:2,300,682...2,313,611 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO (MGI:4430666|PMID:19632177) UniProt PMID:19632177 MGI:4430666 NCBI chrNW_004936586:4,065,767...5,100,690 JBrowse link
G Fgf2 fibroblast growth factor 2 ISO (PMID:9553078) BHF-UCL
RGD
PMID:8603495, PMID:9553078 RGD:8655650 NCBI chrNW_004936662:1,886,176...1,928,998 JBrowse link
G Fgf9 fibroblast growth factor 9 ISO (MGI:3527351|PMID:15621532) MGI PMID:15621532 MGI:3527351 NCBI chrNW_004936720:282,291...316,629 JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 ISO (MGI:3527351|PMID:15621532) RGD
MGI
PMID:15621532, PMID:18275970 MGI:3527351, RGD:10402047 NCBI chrNW_004936710:1,760,365...1,815,269 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO (MGI:3527351|PMID:15621532) MGI PMID:15621532 MGI:3527351 NCBI chrNW_004936486:10,506,680...10,606,272 JBrowse link
G Gata4 GATA binding protein 4 ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Gata6 GATA binding protein 6 ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chrNW_004936550:1,814,336...1,844,399 JBrowse link
G Gli1 GLI family zinc finger 1 ISO (PMID:28583401) BHF-UCL PMID:28583401 NCBI chrNW_004936646:1,622,308...1,629,787 JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 ISO (MGI:3784153|PMID:17332425) MGI PMID:17332425 MGI:3784153 NCBI chrNW_004936639:3,705,225...3,714,696 JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO RGD PMID:26884868 RGD:13800890 NCBI chrNW_004936619:1,889,841...1,932,646 JBrowse link
G Mapk14 mitogen-activated protein kinase 14 ISO (MGI:5288131|PMID:21768366) MGI PMID:21768366 MGI:5288131 NCBI chrNW_004936476:23,237,762...23,310,211 JBrowse link
G Mef2c myocyte enhancer factor 2C ISO (MGI:3830899|PMID:16680724) UniProt PMID:16680724 MGI:3830899 NCBI chrNW_004936469:7,060,480...7,225,497 JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO RGD PMID:19853610 RGD:2325979 NCBI chrNW_004936612:1,262,557...1,556,281 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:4947514|PMID:20007915) BHF-UCL PMID:20007915 MGI:4947514 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
G Nrg1 neuregulin 1 ISO (PMID:9553078) BHF-UCL PMID:9553078 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO (PMID:21474815) BHF-UCL PMID:21474815 NCBI chrNW_004936476:22,295,023...22,300,155 JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chrNW_004936477:3,354,336...3,445,248 JBrowse link
G Tbx2 T-box transcription factor 2 ISO (MGI:3039059|PMID:15042700) BHF-UCL PMID:15042700 MGI:3039059 NCBI chrNW_004936490:2,769,264...2,778,342 JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:3579960|PMID:15901664) BHF-UCL PMID:15901664 MGI:3579960 NCBI chrNW_004936478:10,887,900...10,939,510 JBrowse link
G Tbx5 T-box transcription factor 5 ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chrNW_004936558:7,408,229...7,454,897 JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chrNW_004936537:7,154,125...7,340,218 JBrowse link
G Wnt2 Wnt family member 2 ISO (MGI:4439199|PMID:20159597) MGI PMID:20159597 MGI:4439199 NCBI chrNW_004936589:1,825,209...1,866,898 JBrowse link
G Yap1 Yes1 associated transcriptional regulator ISO (MGI:5509071|PMID:23918388) ARUK-UCL PMID:23918388 MGI:5509071 NCBI chrNW_004936551:5,638,383...5,740,523 JBrowse link
G Zfpm2 zinc finger protein, FOG family member 2 ISO (MGI:5770062|PMID:22267003) BHF-UCL PMID:22267003 MGI:5770062 NCBI chrNW_004936470:38,432,894...38,857,656 JBrowse link
regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chrNW_004936804:52,435...115,289 JBrowse link
G Fgf20 fibroblast growth factor 20 ISO (MGI:4829405|PMID:20713518) MGI PMID:20713518 MGI:4829405 NCBI chrNW_004936573:6,055,261...6,062,764 JBrowse link
G Foxp1 forkhead box P1 ISO (MGI:4829405|PMID:20713518) MGI PMID:20713518 MGI:4829405 NCBI chrNW_004936603:2,631,781...3,146,104 JBrowse link
G Gata4 GATA binding protein 4 ISO (MGI:3581473|PMID:15902305) MGI PMID:15902305 MGI:3581473 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO (MGI:5288131|PMID:21768366) MGI PMID:21768366 MGI:5288131 NCBI chrNW_004936629:542,143...549,861 JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO (MGI:4829405|PMID:20713518) MGI PMID:20713518 MGI:4829405 NCBI chrNW_004936609:2,406,004...2,408,980 JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 ISO (MGI:3820811|PMID:18718461) BHF-UCL PMID:18718461 MGI:3820811 NCBI chrNW_004936524:7,656,523...7,680,043 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12002
    developmental process 5648
      developmental growth 743
        cardiac muscle tissue growth 104
          cardiac muscle cell proliferation 57
            negative regulation of cardiac muscle cell proliferation 17
            positive regulation of cardiac muscle cell proliferation + 28
            regulation of cardiac muscle cell proliferation + 48
Path 2
Term Annotations click to browse term
  biological_process 12002
    developmental process 5648
      anatomical structure development 5286
        multicellular organism development 4845
          system development 4567
            circulatory system development 1105
              heart development 629
                cardiac muscle tissue development 238
                  cardiac muscle tissue growth 104
                    cardiac muscle cell proliferation 57
                      negative regulation of cardiac muscle cell proliferation 17
                      positive regulation of cardiac muscle cell proliferation + 28
                      regulation of cardiac muscle cell proliferation + 48
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.