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ONTOLOGY REPORT - ANNOTATIONS


Term:pericardium development
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Accession:GO:0060039 term browser browse the term
Definition:The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.


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pericardium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 IEA
ISO
GO_REF:0000107
MGI:3583785 (MGI:3611958|PMID:16314491)
Ensembl
RGD
PMID:16314491 GO_REF:0000107, MGI:3611958 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Ccm2 CCM2 scaffold protein ISO MGI:1924696|MGI:3512761 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr14:86,812,728...86,859,408
Ensembl chr14:86,813,082...86,859,406
JBrowse link
G Heg1 heart development protein with EGF-like domains 1 ISO MGI:2384924|MGI:3838392 (MGI:3837878|PMID:19151727) RGD PMID:19151727 MGI:3837878 NCBI chr11:70,234,248...70,322,966
Ensembl chr11:70,236,888...70,322,690
JBrowse link
G Mecom MDS1 and EVI1 complex locus ISO MGI:2158381 (MGI:3686680|PMID:17029558) RGD PMID:17029558 MGI:3686680 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
JBrowse link
G Nkx2-6 NK2 homeobox 6 ISO (PMID:9545560) RGD PMID:9545560 NCBI chr15:51,034,620...51,038,715
Ensembl chr15:51,034,620...51,038,704
JBrowse link
G Rpgrip1l Rpgrip1-like ISO MGI:3716208 (MGI:3715393|PMID:17553904) RGD PMID:17553904 MGI:3715393 NCBI chr19:17,115,266...17,208,055
Ensembl chr19:17,115,412...17,208,055
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO MGI:4437211 (MGI:4431136|PMID:20133625) RGD PMID:20133625 MGI:4431136 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Smad2 SMAD family member 2 ISO MGI:1201674 (MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:3618021 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 ISO MGI:108051 (MGI:3618021|PMID:15183723) RGD PMID:15183723 MGI:3618021 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Tbx5 T-box transcription factor 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:15138308)
Ensembl
UniProt
RGD
PMID:15138308 GO_REF:0000024, GO_REF:0000107 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 ISO MGI:98958 (MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:4830282 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
pericardium morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp5 bone morphogenetic protein 5 ISO UniProtKB:P23359 (MGI:1332253|PMID:10079236) RGD PMID:10079236 MGI:1332253 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO UniProtKB:P49003 (MGI:1332253|PMID:10079236) RGD PMID:10079236 MGI:1332253 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Dll4 delta like canonical Notch ligand 4 ISO (MGI:3056036|PMID:15466159) RGD PMID:15466159 MGI:3056036 NCBI chr 3:111,135,011...111,146,746
Ensembl chr 3:111,135,021...111,145,986
JBrowse link
G Lrp6 LDL receptor related protein 6 IBA
ISO
PMID:21873635
MGI:98958 (MGI:4413372|PMID:19795512)
RGD PMID:19795512, PMID:21873635 MGI:4413372, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:3027664|PMID:14701881), (MGI:4837019|PMID:20890042), (MGI:5298073|PMID:21311046) RGD PMID:14701881, PMID:20890042, PMID:21311046 MGI:3027664, MGI:4837019, MGI:5298073 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO MGI:2155441 (MGI:85697|PMID:9030684) RGD PMID:9030684 MGI:85697 NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:3579960|PMID:15901664) RGD PMID:15901664 MGI:3579960 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Wnt5a Wnt family member 5A ISO MGI:1298218 (MGI:4413372|PMID:19795512) RGD PMID:19795512 MGI:4413372 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A IEA
ISO
GO_REF:0000107
MGI:1857617 (MGI:4830282|PMID:19056682)
Ensembl
RGD
PMID:19056682 GO_REF:0000107, MGI:4830282 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
proepicardium cell migration involved in pericardium morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flrt3 fibronectin leucine rich transmembrane protein 3 ISS
ISO
IEA
GO_REF:0000024
(MGI:3796818|PMID:18448090)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18448090 GO_REF:0000024, GO_REF:0000107, MGI:3796818 NCBI chr 3:134,684,446...134,696,586
Ensembl chr 3:134,683,065...134,696,654
JBrowse link
visceral serous pericardium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 IEA
ISO
GO_REF:0000107
MGI:3715149|MGI:3801682 (MGI:4948416|PMID:21350214)
Ensembl
RGD
PMID:21350214 GO_REF:0000107, MGI:4948416 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Wt1 WT1 transcription factor ISO
IEA
ISS
UniProtKB:P22561 (PMID:10101119)
(MGI:1333093|PMID:10101119)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:10101119 GO_REF:0000024, GO_REF:0000107, MGI:1333093 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        animal organ development 4033
          heart development 687
            pericardium development 21
              pericardium morphogenesis + 9
              visceral serous pericardium development 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              heart development 687
                pericardium development 21
                  pericardium morphogenesis + 9
                  visceral serous pericardium development 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.