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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cardiac muscle cell proliferation
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Accession:GO:0060043 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.
Synonyms:exact_synonym: regulation of heart muscle cell proliferation
 related_synonym: regulation of cardiomyocyte proliferation


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regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A ISO (MGI:3040576|PMID:15073157) BHF-UCL PMID:15073157 MGI:3040576 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
JBrowse link
G FGF20 fibroblast growth factor 20 ISO (MGI:4829405|PMID:20713518) MGI PMID:20713518 MGI:4829405 NCBI chr 8:16,205,791...16,216,257
Ensembl chr 8:13,151,867...13,161,216
JBrowse link
G FOXP1 forkhead box P1 ISO (MGI:4829405|PMID:20713518) MGI PMID:20713518 MGI:4829405 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G GATA4 GATA binding protein 4 ISO (MGI:3581473|PMID:15902305) MGI PMID:15902305 MGI:3581473 NCBI chr 8:7,442,921...7,526,731 JBrowse link
G MAPK11 mitogen-activated protein kinase 11 ISO (MGI:5288131|PMID:21768366) MGI PMID:21768366 MGI:5288131 NCBI chr22:30,492,664...30,499,456
Ensembl chr22:49,492,693...49,495,732
JBrowse link
G NKX2-5 NK2 homeobox 5 ISO (MGI:4829405|PMID:20713518) MGI PMID:20713518 MGI:4829405 NCBI chr 5:168,584,197...168,589,406
Ensembl chr 5:175,492,288...175,495,514
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO (MGI:3820811|PMID:18718461) BHF-UCL PMID:18718461 MGI:3820811 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
negative regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway ISO PMID:28948298 BHF-UCL PMID:28948298 RGD:13464260 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO PMID:26240138 BHF-UCL PMID:26240138 RGD:13210532 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G CXADR CXADR Ig-like cell adhesion molecule ISO (MGI:3709954|PMID:16543498) MGI PMID:16543498 MGI:3709954 NCBI chr21:4,246,779...4,367,369
Ensembl chr21:17,636,952...17,693,324
JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:19377854 RGD:7207421 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G HDAC2 histone deacetylase 2 ISO (MGI:3711360|PMID:17322895) MGI PMID:17322895 MGI:3711360 NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004
JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 ISO PMID:26298346 BHF-UCL PMID:26298346 RGD:11522645 NCBI chr 6:15,100,415...15,376,505
Ensembl chr 6:15,466,050...15,739,170
JBrowse link
G KCNK2 potassium two pore domain channel subfamily K member 2 ISO RGD PMID:24705172 RGD:9831164 NCBI chr 1:190,576,180...190,807,367
Ensembl chr 1:195,430,994...195,662,840
JBrowse link
G MAPK11 mitogen-activated protein kinase 11 ISO (MGI:5288131|PMID:21768366) MGI PMID:21768366 MGI:5288131 NCBI chr22:30,492,664...30,499,456
Ensembl chr22:49,492,693...49,495,732
JBrowse link
G MEIS1 Meis homeobox 1 ISO PMID:28111633 BHF-UCL PMID:28111633 RGD:12911005 NCBI chr2A:66,494,934...66,633,295
Ensembl chr2A:67,615,941...67,752,958
JBrowse link
G NOG noggin ISO (MGI:3783944|PMID:17218603) BHF-UCL PMID:17218603 MGI:3783944 NCBI chr17:50,669,186...50,671,081
Ensembl chr17:55,532,394...55,533,092
JBrowse link
G PTEN phosphatase and tensin homolog ISO (MGI:5584062|PMID:23575307) BHF-UCL PMID:23575307 MGI:5584062 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605
JBrowse link
G RBP4 retinol binding protein 4 ISO (MGI:2655947|PMID:12663486) BHF-UCL PMID:12663486 MGI:2655947 NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887
JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 ISO (MGI:6271967|PMID:30321469) ARUK-UCL PMID:30321469 MGI:6271967 NCBI chr 6:2,893,802...2,943,162
Ensembl chr 6:2,997,343...3,045,078
JBrowse link
G SAV1 salvador family WW domain containing protein 1 ISO (MGI:4948149|PMID:21512031) MGI PMID:21512031 MGI:4948149 NCBI chr14:31,223,140...31,257,871
Ensembl chr14:49,525,687...49,560,347
JBrowse link
G TBX5 T-box transcription factor 5 ISO (PMID:11161571) UniProtKB PMID:11161571 NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO RGD PMID:15537505 RGD:1601597 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856
JBrowse link
G TP73 tumor protein p73 ISO (PMID:18634800) MGI PMID:18634800 NCBI chr 1:2,323,399...2,405,295
Ensembl chr 1:3,476,064...3,529,206
JBrowse link
G VGLL4 vestigial like family member 4 ISO (MGI:6120600|PMID:27720608) UniProt PMID:27720608 MGI:6120600 NCBI chr 3:11,489,805...11,654,507
Ensembl chr 3:11,834,746...11,981,877
JBrowse link
positive regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP10 bone morphogenetic protein 10 ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chr2A:68,901,944...68,912,559
Ensembl chr2A:70,023,655...70,034,420
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A ISO (MGI:3810850|PMID:18667463) BHF-UCL PMID:18667463 MGI:3810850 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
JBrowse link
G CCNB1 cyclin B1 ISO RGD PMID:15253691 RGD:2301353 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332
JBrowse link
G CDK1 cyclin dependent kinase 1 ISO RGD PMID:15253691 RGD:2301353 NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO (MGI:4430666|PMID:19632177) UniProt PMID:19632177 MGI:4430666 NCBI chr2B:98,625,630...99,795,371
Ensembl chr2B:217,069,644...218,272,006
JBrowse link
G FGF2 fibroblast growth factor 2 ISO (PMID:9553078) BHF-UCL
RGD
PMID:8603495, PMID:9553078 RGD:8655650 NCBI chr 4:115,005,136...115,076,369
Ensembl chr 4:126,149,813...126,214,942
JBrowse link
G FGF9 fibroblast growth factor 9 ISO (MGI:3527351|PMID:15621532) MGI PMID:15621532 MGI:3527351 NCBI chr13:2,967,713...3,000,554
Ensembl chr13:21,273,333...21,307,198
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO (MGI:3527351|PMID:15621532) RGD
MGI
PMID:15621532, PMID:18275970 MGI:3527351, RGD:10402047 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO (MGI:3527351|PMID:15621532) MGI PMID:15621532 MGI:3527351 NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815
JBrowse link
G GATA4 GATA binding protein 4 ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chr 8:7,442,921...7,526,731 JBrowse link
G GATA6 GATA binding protein 6 ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chr18:15,411,764...15,444,402 JBrowse link
G GLI1 GLI family zinc finger 1 ISO (PMID:28583401) BHF-UCL PMID:28583401 NCBI chr12:31,453,759...31,466,194
Ensembl chr12:31,710,057...31,722,473
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 ISO (MGI:3784153|PMID:17332425) MGI PMID:17332425 MGI:3784153 NCBI chr 6:123,527,180...123,538,794
Ensembl chr 6:127,647,547...127,659,056
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO RGD PMID:26884868 RGD:13800890 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO (MGI:5288131|PMID:21768366) MGI PMID:21768366 MGI:5288131 NCBI chr 6:35,586,847...35,683,041
Ensembl chr 6:36,788,233...36,871,114
JBrowse link
G MEF2C myocyte enhancer factor 2C ISO (MGI:3830899|PMID:16680724) UniProt PMID:16680724 MGI:3830899 NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426
JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO RGD PMID:19853610 RGD:2325979 NCBI chr11:107,845,507...108,160,441
Ensembl chr11:111,925,677...112,000,401
JBrowse link
G NOTCH1 notch receptor 1 ISO (MGI:4947514|PMID:20007915) BHF-UCL PMID:20007915 MGI:4947514 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
G NRG1 neuregulin 1 ISO (PMID:9553078) BHF-UCL PMID:9553078 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977
JBrowse link
G PIM1 Pim-1 proto-oncogene, serine/threonine kinase ISO (PMID:21474815) BHF-UCL PMID:21474815 NCBI chr 6:36,730,669...36,735,954 JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:3701380|PMID:17336907) BHF-UCL PMID:17336907 MGI:3701380 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683
JBrowse link
G TBX2 T-box transcription factor 2 ISO (MGI:3039059|PMID:15042700) BHF-UCL PMID:15042700 MGI:3039059 NCBI chr17:55,501,932...55,511,537
Ensembl chr17:60,622,098...60,630,189
JBrowse link
G TBX20 T-box transcription factor 20 ISO (MGI:3579960|PMID:15901664) BHF-UCL PMID:15901664 MGI:3579960 NCBI chr 7:35,855,969...35,878,533 JBrowse link
G TBX5 T-box transcription factor 5 ISO (MGI:3833786|PMID:19084512) MGI PMID:19084512 MGI:3833786 NCBI chr12:111,954,222...112,009,261
Ensembl chr12:115,333,609...115,389,739
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO (MGI:2663364|PMID:12773577) BHF-UCL PMID:12773577 MGI:2663364 NCBI chr 1:94,337,275...94,539,229
Ensembl chr 1:93,080,452...93,285,587
JBrowse link
G WNT2 Wnt family member 2 ISO (MGI:4439199|PMID:20159597) MGI PMID:20159597 MGI:4439199 NCBI chr 7:109,244,772...109,291,472
Ensembl chr 7:121,936,031...121,985,862
JBrowse link
G YAP1 Yes1 associated transcriptional regulator ISO (MGI:5509071|PMID:23918388) ARUK-UCL PMID:23918388 MGI:5509071 NCBI chr11:97,061,367...97,186,961
Ensembl chr11:100,552,424...100,681,301
JBrowse link
G ZFPM2 zinc finger protein, FOG family member 2 ISO (MGI:5770062|PMID:22267003) BHF-UCL PMID:22267003 MGI:5770062 NCBI chr 8:101,872,850...102,430,622
Ensembl chr 8:104,023,062...104,576,688
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12567
    regulation of biological process 8677
      regulation of cellular process 8203
        regulation of cell population proliferation 1634
          regulation of cardiac muscle cell proliferation 49
            negative regulation of cardiac muscle cell proliferation 18
            positive regulation of cardiac muscle cell proliferation + 28
Path 2
Term Annotations click to browse term
  biological_process 12567
    developmental process 5840
      anatomical structure development 5453
        multicellular organism development 4985
          system development 4689
            animal organ development 3618
              heart development 636
                cardiac muscle tissue development 242
                  cardiac muscle tissue growth 107
                    regulation of cardiac muscle tissue growth 78
                      regulation of cardiac muscle cell proliferation 49
                        negative regulation of cardiac muscle cell proliferation 18
                        positive regulation of cardiac muscle cell proliferation + 28
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.